Results 81 to 90 of about 485,986 (267)

The resident gut microbiome modulates the effect of synbiotics on the immunogenicity after SARS-COV-2 vaccination in elderly and diabetes patients

npj Biofilms and Microbiomes
The study aims to tackle the seed and soil microbiome and mechanisms that contribute to the effect of synbiotics in enhancing immunogenicity after SARS-CoV-2 vaccination in elderly and diabetic patients. Among 369 subjects who received 3 months of SIM01,
Lin Zhang, Shilan Wang, Martin C. S. Wong, Chris K. P. Mok, Jessica Y. L. Ching, Joyce W. Y. Mak, Chunke Chen, Bing Huo, Shuai Yan, Chun Pan Cheung, Emily O. L. Chiu, Emily Y. T. Fung, Pui Kuan Cheong, Francis K. L. Chan, Siew C. Ng   +14 more
doaj   +1 more source

Gut: The gate and key to brain

Chinese Medical Journal
. Brain science is the frontier of modern science, and new advances have been made in brain-like designs and brain-computer interfaces to simulate or develop brain functions.
Xiaohan Zhang, Yunsheng Yang, Xiangxiang Pan   +2 more
doaj   +1 more source

Oral Bioinspired Peroxisome‐Engineered Probiotics for Modulating Gut Microbiota Homeostasis and Alleviating Cardiac Chemotherapy Toxicity

Advanced Science, EarlyView.
This study developed an oral bioinspired peroxisome‐engineered probiotic (BPEP) by anchoring lipid‐encapsulated ruthenium nanozymes onto Escherichia coli Nissle 1917, utilizing probiotics to deliver nanozymes to the intestinal barrier for reactive oxygen species/reactive nitrogen species elimination, tight junction restoration, and gut microbiota ...
Shuyu Wang, Xiaowan Fan, Chao Zhang, Shuai Han, Yike Guo, Yuchen Wang, Wei Wang, Junyue Xing, Ying Liu, Wei Jiang, Xiaoying Chen   +10 more
wiley   +1 more source

Molecular characterisation of selected gastrointestinal microbiota in South African HIV-positive patients during HAART

, 2012
Includes bibliographical references.Progression of the HIV disease is characterised by a massive depletion of CD4+ T cells and it has been shown that patients living with a more advanced HIV infection have a higher risk of developing diarrhoea due to the
Du Plessis, Sarah Jane
core  

Metatranscriptome analysis of the human fecal microbiota reveals subject-specific expression profiles, with genes encoding proteins involved in carbohydrate metabolism being dominantly expressed

, 2010
The human gastrointestinal (GI) tract provides home to a complex microbial community, collectively termed microbiota. Although major efforts have been made to describe the diversity and stability of the microbiota, functional studies have been largely ...
Vos, W.M., de, Kleerebezem, M., Smidt, H., Zoetendal, E.G., te Boekhorst, J., Hauke Smidt, Booijink, C.C.G.M., Erwin G. Zoetendal, Carien C. G. M. Booijink, Boekhorst, J., te, Michiel Kleerebezem, Jos Boekhorst, Willem M. de Vos, de Vos, W.M.   +13 more
core   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Evaluating the microbial diversity of an in vitro model of the human large intestine by phylogenetic microarray analysis

, 2010
A high-density phylogenetic microarray targeting small subunit rRNA (SSU rRNA) sequences of over 1000 microbial phylotypes of the human gastrointestinal tract, the HITChip, was used to assess the impact of faecal inoculum preparation and operation ...
Vos, W.M., de, Heilig, H.G.H.J., Vos, W.M.de, Smidt, H., Mirjana Rajilić-Stojanović, de Vos, Willem M., Rajilic-Stojanovic, M., Rajilić-Stojanović, Mirjana, Koen Venema, Maathuis, A., Hauke Smidt, Maathuis, Annet, Smidt, Hauke, Hans G. H. J. Heilig, Venema, Koen, Willem M. de Vos, Heilig, G.H.J., Annet Maathuis, de Vos, W.M., Heilig, Hans G. H. J., Venema, K.   +20 more
core   +1 more source

Gut Microbiota and Immune System Interactions

, 2020
Dynamic interactions between gut microbiota and a host’s innate and adaptive immune systems are essential in maintaining intestinal homeostasis and inhibiting inflammation.
Maureen Groer, Anujit Sarkar, Ji Yoo, Samia Dutra, Daniel McSkimming   +4 more
core   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Sex-dependent effects of a high-fat diet on the hypothalamic response in mice

Biology of Sex Differences
Sex differences in rodent models of diet-induced obesity are still poorly documented, particularly regarding how central mechanisms vary between sexes in response to an obesogenic diet.
Virginie Dreux, Candice Lefebvre, Charles-Edward Breemeersch, Colin Salaün, Christine Bôle-Feysot, Charlène Guérin, Pierre Déchelotte, Alexis Goichon, Moïse Coëffier, Ludovic Langlois   +9 more
doaj   +1 more source