Results 61 to 70 of about 1,058,188 (349)

The intestinal microbiota and cardiovascular disease [PDF]

open access: yesCardiovascular Research, 2019
AbstractThe intestinal microbiota of human hosts is the community of microorganisms living in the small and, mainly, the large intestine of humans. This microbial ecosystem has co-evolved with humans across the millennia, has come to play an important interactive role in human physiology and has been aptly called our forgotten organ.
Themistoklis Katsimichas   +5 more
openaire   +2 more sources

Intestinal barrier permeability: the influence of gut microbiota, nutrition, and exercise

open access: yesFrontiers in Physiology
The intestinal wall is a selectively permeable barrier between the content of the intestinal lumen and the internal environment of the body. Disturbances of intestinal wall permeability can potentially lead to unwanted activation of the enteric immune ...
Tetiana R Dmytriv   +2 more
semanticscholar   +1 more source

Intestinal microbiota and its interaction to intestinal health in nursery pigs

open access: yesAnimal Nutrition, 2021
The intestinal microbiota has gained increased attention from researchers within the swine industry due to its role in promoting intestinal maturation, immune system modulation, and consequently the enhancement of the health and growth performance of the
M. E. Duarte, S. Kim
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Multi-target regulation of intestinal microbiota by berberine to improve type 2 diabetes mellitus

open access: yesFrontiers in Endocrinology, 2022
Type 2 diabetes mellitus (T2DM) and its complications are major public health problems that seriously affect the quality of human life. The modification of intestinal microbiota has been widely recognized for the management of diabetes.
Qiongyao He   +6 more
doaj   +1 more source

Intestinal microbiota and nonalcoholic steatohepatitis [PDF]

open access: yesCurrent Opinion in Gastroenterology, 2017
Nonalcoholic fatty liver disease (NAFLD) is a liver disease with high prevalence in western countries. Progression from NAFLD to nonalcoholic steatohepatitis (NASH) occurs in 10-20%. NASH pathogenesis is multifactorial including genetic and environmental factors.
Katharina, Brandl, Bernd, Schnabl
openaire   +2 more sources

Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity

open access: yesNature Communications, 2020
Innate lymphoid cells (ILCs) and CD4+ T cells produce IL-22, which is critical for intestinal immunity. The microbiota is central to IL-22 production in the intestines; however, the factors that regulate IL-22 production by CD4+ T cells and ILCs are not ...
Wenjing Yang   +15 more
semanticscholar   +1 more source

Effects of Four Antibiotics on the Diversity of the Intestinal Microbiota

open access: yesbioRxiv, 2021
The intestinal microbiota is a dynamic community of hundreds of millions of microorganisms that play important roles in human health. However, treatment with antibiotics can disrupt the delicate balance of this community, leading to deleterious effects ...
Ce Huang   +3 more
semanticscholar   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

An Insight Into Intestinal Microbiota of Spontaneously Hypertensive Rats After Valsartan Administration

open access: yesDose-Response, 2021
It has been proven a close relationship between intestinal microbiota and hypertension. Valsartan is a widely used ARB antihypertensive drug; so far, the effect of valsartan on intestinal microbiota remains largely unexplored.
Ying-Zi Qi   +5 more
doaj   +1 more source

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