Results 61 to 70 of about 222,945 (312)

Phylogenomic analysis of the collagen-like BclA proteins in Clostridioides difficile

Applied and Environmental Microbiology
Clostridioides difficile is a Gram-positive, anaerobic, spore-forming bacterium and a major nosocomial pathogen, notable for its high genetic diversity. C.
Francisca Cid-Rojas, Enzo Guerrero-Araya, Christian Brito-Silva, Marjorie Pizarro-Guajardo, César Rodríguez, Daniel Paredes-Sabja   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Avaliação da microbiota intestinal e sua relação com parâmetros metabólicos em mulheres com obesidade mórbida [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Nutrição, Florianópolis, 2014Introdução: A microbiota intestinal refere-se aos micro-organismos que reside no trato ...
Beserra, Bruna Teles Soares
core  

The Genome of Akkermansia muciniphila, a Dedicated Intestinal Mucin Degrader, and Its Use in Exploring Intestinal Metagenomes [PDF]

, 2011
Background: The human gastrointestinal tract contains a complex community of microbes, fulfilling important health-promoting functions. However, this vast complexity of species hampers the assignment of responsible organisms to these functions. Recently,
Willem M de Vos, Kant Ravi, van Passel, Mark W. J., Mark Van Passel, Zoetendal, Erwin G., Chain, Patrick S. G., de Vos Willem M., Chain Patrick S. G., van Passel Mark W. J., Hauke Smidt, Derrien Muriel, Patrick S G Chain, Derrien, Muriel, Airi Palva, Palva Airi, Derrien, M.M.N., Malfatti, Stephanie A., Woyke, Tanja, Malfatti, S.A., Mark W J van Passel, Caroline M Plugge, Ravi Kant, Tanja Woyke, Kant, R., Muriel Derrien, Smidt, Hauke, Erwin G Zoetendal, Willem M. De Vos, Vos, W.M., de, Smidt, H., Malfatti Stephanie A., Mark W. J. Van Passel, Erwin G. Zoetendal, Plugge Caroline M., Plugge, Caroline M., de Vos, Willem M., Zoetendal, E.G., Stephanie A. Malfatti, Patrick S. G. Chain, Palva, Airi, Smidt Hauke, Plugge, C.M., Caroline M. Plugge, Passel, M.W.J., van, Kant, Ravi, Woyke Tanja, Stephanie A Malfatti, Zoetendal Erwin G., Palva, A.   +48 more
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The SERPINB4 gene mutation identified in twin patients with Crohn’s disease impaires the intestinal epithelial cell functions

Scientific Reports
Crohn’s disease (CD) is a chronic inflammatory autoimmune disease of unknown etiology. To identify new targets related to the initiation of CD, we screened a pair of twins with CD, which is a rare phenomenon in the Chinese population, for genetic ...
Xiao-Mei Ouyang, Jun-Hui Lin, Ying Lin, Xian-Ling Zhao, Ya‐Ni Huo, Lai-Ying Liang, Yong-Dong Huang, Gui-Jing Xie, Peng Mi, Zhen-Yu Ye, Bayasi Guleng   +10 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Molecular characterisation of selected gastrointestinal microbiota in South African HIV-positive patients during HAART [PDF]

, 2012
Includes bibliographical references.Progression of the HIV disease is characterised by a massive depletion of CD4+ T cells and it has been shown that patients living with a more advanced HIV infection have a higher risk of developing diarrhoea due to the
Du Plessis, Sarah Jane
core  

An investigation of horizontal transfer of feed introduced DNA to the aerobic microbiota of the gastrointestinal tract of rats [PDF]

, 2012
BACKGROUND: Horizontal gene transfer through natural transformation of members of the microbiota of the lower gastrointestinal tract (GIT) of mammals has not yet been described.
Raddadi Noura, Nielsen KM, Traavik T, Terje Traavik, Brusetti Lorenzo, Averhoff, Beate, Nordgård Lise, Beate Averhoff, Nordgård, Lise, Noura Raddadi, Brusetti L, Nielsen, Kaare Magne, Kaare Magne Nielsen, Traavik, Terje, Nielsen Kaare, Traavik Terje, Lorenzo Brusetti, Raddadi, Noura, Averhoff B, Brusetti, Lorenzo, Averhoff Beate, Nordgård L, Lise Nordgard   +22 more
core   +1 more source

Assessment of chemical methods in the extraction of spore surface layers in Clostridioides difficile spores

mSphere
Clostridioides difficile spores are essential for initiation, recurrence, and transmission of C. difficile infections (CDI). These outermost layers of the spore, the exosporium and spore coat, are responsible for initial interactions with the host and ...
Javier Sanchez, Alba Romero-Rodriguez, Scarlett Troncoso-Cotal, Morgan S. Osborne, Theresa Ariri, Joseph A. Sorg, Daniel Paredes-Sabja   +6 more
doaj   +1 more source

Characteristics and early development of intestinal microbiota in piglets

Siliao yanjiu, 2022
There are dense, dynamic and highly complex microbial communities in pig intestine. Intestinal microbiota plays an important role in promoting intestinal maturation, regulating the immune system, enhancing the health and growth performance of host ...
ZHAO Huai-bao
doaj