Results 81 to 90 of about 687,509 (312)

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

Analyzing the functionality of the human intestinal microbiota by stable isotope probing [PDF]

, 2010
Key words: gut bacteria, dietary carbohydrates, digestion, RNA-SIP, TIM-2, HITChip, human trial The human gastro-intestinal (GI) tract comprises a series of complex and dynamic organs ranging from the stomach to the distal colon, which harbor immense ...
Kovatcheva, P.P.
core  

Towards a safer probiotic: clbD deletion attenuates EcN-induced DNA damage responses and epithelial inflammatory transcriptional responses

Frontiers in Cellular and Infection Microbiology
Escherichia coli Nissle 1917 (EcN) is widely used as a probiotic and engineering chassis, but its carriage of the pks genomic island raises safety concerns related to the genotoxin colibactin.
Wei-Ming Chen, Wei-Ming Chen, Wei-Ming Chen, Ming-Yang Sun, Ming-Yang Sun, Ming-Yang Sun, Ji-Yuan Ye, Ji-Yuan Ye, Ji-Yuan Ye, De-Cheng Tan, De-Cheng Tan, De-Cheng Tan, Zi-Yi Zhang, Zi-Yi Zhang, Zi-Yi Zhang, Jing-Jing Liu, Jing-Jing Liu   +16 more
doaj   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Enteric opportunistic infections in patients with inflammatory bowel disease receiving biologic therapies: a retrospective cohort study

Gut Pathogens
Background Biologic therapy has improved outcomes in inflammatory bowel disease (IBD) but may predispose patients to enteric opportunistic infections. Asian data comparing infection risk across biologic classes remain scarce.
Ting-Chieh Huang, Tony Kou, Chia-Jung Kuo, Cheng-Hsun Chiu, Tai-Di Chen, Chien-Ming Chen, Jen-Wei Chou, Tien-Yu Huang, Chen-Wang Chang, Cheng-Tang Chiu, Ming-Yao Su, Yu-Bin Pan, Puo-Hsien Le   +12 more
doaj   +1 more source

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

Development of the intestinal microbiota in the piglet

The Journal of General and Applied Microbiology, 2005
The intestinal commensal microbiota of monogastricanimals such as humans and pigs comprise hundredsof different types of microorganisms (Conway, 1995;Savage, 1977). In the last several decades, the role ofthe intestinal commensal microbiota in a wide range ofhost’s physiological functions has been increasinglyrecognized (Cummings and Macfarlane, 1997).
Inoue, Ryo, Tsukahara, Takamitsu, Nakanishi, Nobuo, Ushida, Kazunari   +3 more
openaire   +3 more sources

Intestinal microbiota, diet and health [PDF]

British Journal of Nutrition, 2013
The human intestine is colonised by 1013to 1014micro-organisms, the vast majority of which belong to the phyla Firmicutes and Bacteroidetes. Although highly stable over time, the composition and activities of the microbiota may be influenced by a number of factors including age, diet and antibiotic treatment.
Susan E, Power, Paul W, O'Toole, Catherine, Stanton, R Paul, Ross, Gerald F, Fitzgerald   +4 more
openaire   +2 more sources

[Intestinal microbiota].

Bulletin de l'Academie nationale de medecine, 2016
The human body normally lives in symbiosis with a considerable microscopic environment present on all interfaces with the external environment; it hosts ten times more microbes (microbiota) that it has somatic or germ cells, representing a gene diversity (microbiome) 100-150 times higher than the human genome. These germs are located mainly in the gut,
Patrice, Debré, Jean-Yves, Le Gall
openaire   +3 more sources

Human milk oligosaccharides: bridging the gap in intestinal microbiota between mothers and infants

Frontiers in Cellular and Infection Microbiology
Breast milk is an essential source of infant nutrition. It is also a vital determinant of the structure and function of the infant intestinal microbial community, and it connects the mother and infant intestinal microbiota.
Wen Sun, Lin Tao, Chen Qian, Pei-pei Xue, Si-si Du, Ying-na Tao   +5 more
doaj   +1 more source