Results 71 to 80 of about 844,915 (312)

Phylogenomic analysis of the collagen-like BclA proteins in Clostridioides difficile

open access: yesApplied and Environmental Microbiology
Clostridioides difficile is a Gram-positive, anaerobic, spore-forming bacterium and a major nosocomial pathogen, notable for its high genetic diversity. C.
Francisca Cid-Rojas   +5 more
doaj   +1 more source

Multi-target regulation of intestinal microbiota by berberine to improve type 2 diabetes mellitus

open access: yesFrontiers in Endocrinology, 2022
Type 2 diabetes mellitus (T2DM) and its complications are major public health problems that seriously affect the quality of human life. The modification of intestinal microbiota has been widely recognized for the management of diabetes.
Qiongyao He   +6 more
doaj   +1 more source

Pathogenic mechanism of intestinal microbiota involved in Guillain-Barre syndrome and with Bifidobacterium intervention

open access: yes, 2021
Introduction Guillain-Barré syndrome (GBS) is an acute immune-mediated polyneuropathy, involving the peripheral nervous system. The pathogenicity of GBS involves Th17/Treg imbalance, which may be affected by intestinal microbiota. From the previous study,
Peng Shi   +7 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

The SERPINB4 gene mutation identified in twin patients with Crohn’s disease impaires the intestinal epithelial cell functions

open access: yesScientific Reports
Crohn’s disease (CD) is a chronic inflammatory autoimmune disease of unknown etiology. To identify new targets related to the initiation of CD, we screened a pair of twins with CD, which is a rare phenomenon in the Chinese population, for genetic ...
Xiao-Mei Ouyang   +10 more
doaj   +1 more source

Characteristics and early development of intestinal microbiota in piglets

open access: yesSiliao yanjiu, 2022
There are dense, dynamic and highly complex microbial communities in pig intestine. Intestinal microbiota plays an important role in promoting intestinal maturation, regulating the immune system, enhancing the health and growth performance of host ...
ZHAO Huai-bao
doaj  

Developmental Change of Yolk Microbiota and Its Role on Early Colonization of Intestinal Microbiota in Chicken Embryo

open access: yesAnimals, 2021
Although the fertilized eggs were found to contain microbes in early studies, the detailed composition of yolk microbiota and its influence on embryo intestinal microbiota have not been satisfactorily examined yet.
Peng Ding   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Assessment of chemical methods in the extraction of spore surface layers in Clostridioides difficile spores

open access: yesmSphere
Clostridioides difficile spores are essential for initiation, recurrence, and transmission of C. difficile infections (CDI). These outermost layers of the spore, the exosporium and spore coat, are responsible for initial interactions with the host and ...
Javier Sanchez   +6 more
doaj   +1 more source

Effect of Dose and Timing of Burdock (Arctium lappa) Root Intake on Intestinal Microbiota of Mice

open access: yes, 2020
Water-soluble dietary fiber such as inulin improves the beta diversity of the intestinal microbiota of mice fed with a high-fat diet (HFD). The circadian clock is the system that regulates the internal daily rhythm, and it affects the pattern of beta ...
Aya Watanabe   +5 more
core   +1 more source

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