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Phenotyping the Microcirculation [PDF]

Hypertension, 2012
The role of the microcirculation is increasingly being recognized in the pathophysiology of cardiovascular disease.1,2 The microcirculation is a major site of damage in most target organs of cardiovascular disease, such as the heart, brain, and kidney. Both functional and structural alterations in the small arteries, arterioles, and capillaries are the
Struijker-Boudier, Harry A.J., Heijnen, Bart F.J., Liu, Yan-Ping, Staessen, Jan A.   +3 more
openaire   +4 more sources

Advances in translational imaging of the microcirculation

Microcirculation, 2021
The past few decades have seen an explosion in the development and use of methods for imaging the human microcirculation during health and disease. The confluence of innovative imaging technologies, affordable computing power, and economies of scale have
M. Guerraty, Akanksha Bhargava, J. Senarathna, A. Mendelson, A. Pathak   +4 more
semanticscholar   +1 more source

Genes ingenuity pathway analysis unveils smoothelin‐like 1 (SMTNL1) as a key regulatory protein involved in sodium pentobarbital‐induced growth inhibition in breast cancer

Pharmacology Research & Perspectives, 2023
We previously reported that sodium pentobarbital inhibited the growth of the breast cancer associated with the normalization of microcirculatory hemodynamics and oxygenation.
Bingwei Li, Xiaoyan Zhang, Xueting Liu, Ailing Li, Jianqun Han   +4 more
doaj   +1 more source

Interaction of Estradiol and Endoplasmic Reticulum Stress in the Development of Esophageal Carcinoma

Frontiers in Endocrinology, 2020
Gender differences in esophageal cancer patients indicate that estradiol may have antitumor effects on esophageal cancer. The initiation of endoplasmic reticulum stress (ERS) can induce apoptosis in esophageal cancer cells.
Chen Wang, Peng Wang, Jun-Chao Liu, Jun-Chao Liu, Zhen-Ao Zhao, Rui Guo, Ying Li, Ya-Sen Liu, Shu-Guang Li, Shu-Guang Li, Zi-Gang Zhao   +10 more
doaj   +1 more source

Evaluation of Signal Degradation Due to Birefringence in a Multiple Reference Optical Coherence Tomography System With Polarization-Based Balanced Detection

IEEE Photonics Journal, 2022
Although time-domain optical coherence tomography (TD-OCT) systems are straightforward to realize, the imaging speed, sensitivity, and imaging depth limit their range of applications.
Anand Arangath, Kai Neuhaus, Sergey Alexandrov, Martin Leahy   +3 more
doaj   +1 more source

Simple Characterization Scheme for Optical Coherence Tomography Systems With Application to a Commercial and a Near-Isometric Resolution Fibre-Based System

IEEE Photonics Journal, 2022
Optical Coherence Tomography (OCT) is a rapidly growing imaging modality in biomedical optics. OCT can perform high-resolution, cross-sectional imaging of the microstructure of biological tissues by measuring the coherent spectrum from the backscattered ...
Rajib Dey, Yi Zhou, Kai Neuhaus, Sergey Alexandrov, Andrew Nolan, Ting-Chiao Chang, Martin Leahy   +6 more
doaj   +1 more source

Age‐related changes in the coronary microcirculation influencing the diagnostic performance of invasive pressure‐based indices and long‐term patient prognosis

Catheterization and Cardiovascular Interventions, Volume 100, Issue 7, Page 1195-1205, December 1, 2022., 2022
Abstract Objectives Investigate age‐related changes in coronary microvascular function, its effect on hyperemic and non‐hyperemic indices of stenosis relevance, and its prognostic implications. Background Evidence assessing the effect of age on fractional flow reserve (FFR), resting mean distal intracoronary pressure/mean aortic pressure (Pd/Pa), and ...
Daniel Faria, Hernan Mejia‐Renteria, Joo Myung Lee, Seung Hun Lee, Alejandro Travieso, Ji‐Hyun Jung, Joon‐Hyung Doh, Chang‐Wook Nam, Eun‐Seok Shin, Masahiro Hoshino, Tomoyo Sugiyama, Yoshihisa Kanaji, Nieves Gonzalo, Tsunekazu Kakuta, Bon‐Kwon Koo, Javier Escaned   +15 more
wiley   +1 more source

Comparison of an automatic analysis and a manual analysis of conjunctival microcirculation in a sheep model of haemorrhagic shock [PDF]

, 2016
Life-threatening diseases of critically ill patients are known to derange microcirculation. Automatic analysis of microcirculation would provide a bedside diagnostic tool for microcirculatory disorders and allow immediate therapeutic decisions based upon
Arnemann, Philip-Helge, Ertmer, Christian, Hessler, Michael, Kampmeier, Tim, Morelli, Andrea, Rehberg, Sebastian, Van Aken, Hugo Karel, Westphal, Martin   +7 more
core   +1 more source

Therapeutic mechanisms of mesenchymal stem cells in acute respiratory distress syndrome reveal potentials for Covid-19 treatment

Journal of Translational Medicine, 2021
The mortality rate of critically ill patients with acute respiratory distress syndrome (ARDS) is 30.9% to 46.1%. The emergence of the coronavirus disease 2019 (Covid-19) has become a global issue with raising dire concerns.
Wendi Wang, Wei Lei, Lina Jiang, Siqi Gao, Shijun Hu, Zi-Gang Zhao, Chun-Yu Niu, Zhen-Ao Zhao   +7 more
doaj   +1 more source

A new complimentary web-based tool for manual analysis of microcirculation videos: validation of the capillary mapper against the current gold standard AVA 3.2 [PDF]

, 2018
OBJECTIVE: The aim of the current study was to compare a newly developed web-based freely accessible software program for manual analysis of the microcirculation, the Capillary Mapper (CM), with AVA 3.2 software (AVA; MicroVision Medical B.V., Amsterdam,
Arnemann, Philip-Helge, Ertmer, Christian, Hessler, Michael, Ince, Can, Kampmeier, Tim-Gerald, Kathöfer, Ulrich, Morelli, Andrea, Rehberg, Sebastian Willy, Seidel, Laura, Zamit, Frédéric   +9 more
core   +2 more sources