Results 11 to 20 of about 4,589 (186)

Bioinformatics-based identification of RAS disequilibrium involved in post-hemorrhagic shock mesenteric lymph return-mediated acute kidney injury in mice [PDF]

PeerJ
Post-hemorrhagic shock mesenteric lymph (PHSML) return plays a critical role in the development of acute kidney injury (AKI). However, the molecular mechanism underlying PHSML-mediated AKI remains unclear.
Yujie Jin, Jing Wang, Shaoxuan Wang, Yuting Li, Kun Su, Niuniu Feng, Huibo Du, Limin Zhang, Xiuhong Yang, Chun-Yu Niu, Zi-Gang Zhao   +10 more
doaj   +2 more sources

Effect of Resveratrol on Blood Rheological Properties in LPS-Challenged Rats

Frontiers in Physiology, 2018
Objectives: Abnormal rheological properties induce adverse effects during sepsis. This study sought to investigate the hypothesis that resveratrol (Res) improves blood rheological properties in rats following a lipopolysaccharide (LPS) challenge, and ...
Ying Wang, Ying Wang, Hao Cui, Fei Niu, Shuo-Lin Liu, Yao Li, Li-Min Zhang, Hui-Bo Du, Zi-Gang Zhao, Chun-Yu Niu   +9 more
doaj   +1 more source

Therapeutic mechanisms of mesenchymal stem cells in acute respiratory distress syndrome reveal potentials for Covid-19 treatment

Journal of Translational Medicine, 2021
The mortality rate of critically ill patients with acute respiratory distress syndrome (ARDS) is 30.9% to 46.1%. The emergence of the coronavirus disease 2019 (Covid-19) has become a global issue with raising dire concerns.
Wendi Wang, Wei Lei, Lina Jiang, Siqi Gao, Shijun Hu, Zi-Gang Zhao, Chun-Yu Niu, Zhen-Ao Zhao   +7 more
doaj   +1 more source

p53 SUMOylation Mediates AOPP-Induced Endothelial Senescence and Apoptosis Evasion

Frontiers in Cardiovascular Medicine, 2022
The aging of endothelial cells plays a critical role in the development of age-related vascular disease. We established a model of endothelial premature senescence by application of Advanced oxidation protein products (AOPPs) modified bovine serum ...
Yanjia Chen, Yanjia Chen, Zhuanhua Liu, Hongyu Chen, Xingfu Huang, Xiaoxia Huang, Yang Lei, Qing Liang, Jiayi Wei, Qin Zhang, Xiaohua Guo, Qiaobing Huang   +11 more
doaj   +1 more source

Renal microcirculation.

Folia Pharmacologica Japonica, 1999
The blood flow to the kidney averages about 20% of the cardiac output and the renal circulation affects urine formation. The renal microcirculation is unique. Glomerular circulation is mainly regulated by two resistance arterioles, the afferent arteriole and the efferent arteriole.
T, Tamaki, M, Yoshizumi
openaire   +3 more sources

Contrast agents for photoacoustic imaging: a review of stem cell tracking

Stem Cell Research & Therapy, 2021
With the advent of stem cell therapy for spinal cord injuries, stroke, burns, macular degeneration, heart diseases, diabetes, rheumatoid arthritis and osteoarthritis; the need to track the survival, migration pathways, spatial destination and ...
Soorya James, Kai Neuhaus, Mary Murphy, Martin Leahy   +3 more
doaj   +1 more source

Absolute Circulating Pericyte Progenitor Cell Counts in Mice by Flow Cytometry: comparison of 2 single-platform technologies

The International Journal of Biological Markers, 2015
Background Accumulating evidence indicates that circulating pericyte progenitor cells (CPPCs) may be angiogenic biomarkers in cancer and diabetes. Their validity as biomarkers depends on the accuracy of techniques used for enumeration.
Xiaochen Yuan, Qingbin Wu, Hongwei Li, Bingwei Li, Ruijuan Xiu MD, PhD   +4 more
doaj   +1 more source

Chinese herbal remedies affecting thrombosis and hemostasis: A review

World Journal of Traditional Chinese Medicine, 2015
Acute coronary syndrome, stroke and other ischemic events continue to be the most common causes of mortality and morbidity in the world, and their incidence is rapidly increasing in the developing nations.
Quan Li, Jing-Yu Fan, Jing-Yan Han
doaj   +1 more source

Ameliorating effects of traditional Chinese medicine preparation, Chinese materia medica and active compounds on ischemia/reperfusion-induced cerebral microcirculatory disturbances and neuron damage

Acta Pharmaceutica Sinica B, 2015
Ischemic stroke and ischemia/reperfusion (I/R) injury induced by thrombolytic therapy are conditions with high mortality and serious long-term physical and cognitive disabilities. They have a major impact on global public health.
Kai Sun, Jingyu Fan, Jingyan Han
doaj   +1 more source

Growth differentiation factor 11 attenuates cardiac ischemia reperfusion injury via enhancing mitochondrial biogenesis and telomerase activity

Cell Death and Disease, 2021
It has been reported that growth differentiation factor 11 (GDF11) protects against myocardial ischemia/reperfusion (IR) injury, but the underlying mechanisms have not been fully clarified.
Lin Chen, Guangjin Luo, Yameng Liu, Hairuo Lin, Cankun Zheng, Dongxiao Xie, Yingqi Zhu, Lu Chen, Xiaoxia Huang, Donghong Hu, Jiahe Xie, Zhenhuan Chen, Wangjun Liao, Jianping Bin, Qiancheng Wang, Yulin Liao   +15 more
doaj   +1 more source