Results 31 to 40 of about 4,589 (186)

Improving vasculoprotective effects of MSCs in coronary microvessels – benefits of 3D culture, sub-populations and heparin

Frontiers in Immunology, 2023
IntroductionOpening occluded coronary arteries in patients with myocardial infarction (MI) damages the delicate coronary microvessels through a process called myocardial ischaemia-reperfusion injury.
Kobkaew Bumroongthai, Dean P. J. Kavanagh, Paul Genever, Neena Kalia   +3 more
doaj   +1 more source

Comparative study of the effects of cigarette smoke versus next generation tobacco and nicotine product extracts on endothelial function

Redox Biology, 2021
Tobacco smoking and hemodynamic forces are key stimuli for the development of endothelial dysfunction. As an alternative to smoking, next generation tobacco and nicotine products (NGP) are now widely used.
Sindy Giebe, Anja Hofmann, Melanie Brux, Frazer Lowe, Damien Breheny, Henning Morawietz, Coy Brunssen   +6 more
doaj   +1 more source

Accessing depth-resolved high spatial frequency content from the optical coherence tomography signal

Scientific Reports, 2021
Optical coherence tomography (OCT) is a rapidly evolving technology with a broad range of applications, including biomedical imaging and diagnosis. Conventional intensity-based OCT provides depth-resolved imaging with a typical resolution and sensitivity
Sergey Alexandrov, Anand Arangath, Yi Zhou, Mary Murphy, Niamh Duffy, Kai Neuhaus, Georgina Shaw, Ryan McAuley, Martin Leahy   +8 more
doaj   +1 more source

Bioinformatics exploration of potential common therapeutic targets for systemic and pulmonary arterial hypertension-induced myocardial hypertrophy

Acta Biochimica et Biophysica Sinica, 2023
Systemic and pulmonary arterial hypertension (PAH) can induce left and right ventricular hypertrophy, respectively, but common therapeutic targets for both left and right hypertrophy are limited.
Chen Lu, Li Mingjue, Shen Mengjia, Zhu Yingqi, Chen Kaitong, Huang Xiaoxia, Zheng Cankun, Wang Qiancheng, Lin Hairuo, Liao Wangjun, Bin Jianping, Ma Siyuan, Liao Yulin   +12 more
doaj   +1 more source

MYCOPHENOLATE MOFETIL TREATMENT REDUCES THE RISK OF TREATMENT ESCALATION DUE TO VASCULAR COMPLICATIONS IN LIMITED CUTANEOUS SYSTEMIC SCLEROSIS: EMULATION OF A TARGET TRIAL FROM ITALIAN RHEUMATOLOGY SOCIETY SPRING REGISTRY

Arthritis Care &Research, Accepted Article.
Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis, Gerlando Natalello, Rossella De Angelis, Lucrezia Verardi, Dilia Giuggioli, Gianluigi Bajocchi, Lorenzo Dagna, Silvia Bellando‐Randone, Giovanni Zanframundo, Rosario Foti, Fabio Cacciapaglia, Giovanna Cuomo, Alarico Ariani, Edoardo Rosato, Gemma Lepri, Francesco Girelli, Valeria Riccieri, Elisabetta Zanatta, Ilaria Cavazzana, Francesca Ingegnoli, Maria De Santis, Giuseppe Murdaca, Giuseppina Abignano, Giorgio Pettiti, Alessandra Della Rossa, Maurizio Caminiti, Annamaria Iuliano, Giovanni Ciano, Lorenzo Beretta, Gianluca Bagnato, Ennio Lubrano, Maria Ilenia De Andres, Alessandro Giollo, Cosimo Bruni, Martina Orlandi, Marco Fornaro, Marta Saracco, Cecilia Agnes, Pier Giacomo Cerasuolo, Gabriella Alonzi, Edoardo Cipolletta, Federica Lumetti, Amelia Spinella, Luca Magnani, Corrado Campochiaro, Giacomo De Luca, Veronica Codullo, Elisa Visalli, Carlo Iandoli, Antonietta Gigante, Greta Pellegrino, Erika Pigatto, Maria‐Grazia Lazzaroni, Franco Franceschini, Elena Generali, Gianna Mennillo, Simone Barsotti, Giuseppa Pagano Mariano, Federica Furini, Licia Vultaggio, Simone Parisi, Clara Lisa Peroni, Gerolamo Bianchi, Enrico Fusaro, Gian Domenico Sebastiani, Marcello Govoni, Salvatore D'Angelo, Franco Cozzi, Fabrizio Conti, Serena Guiducci, Andrea Doria, Carlo Salvarani, Florenzo Iannone, Maria Antonietta D'Agostino, Clodoveo Ferri, Marco Matucci Cerinic, Silvia Laura Bosello, on behalf of SPRING collaborators   +77 more
wiley   +1 more source

Role of GABRD Gene Methylation in the Nucleus Accumbens in Heroin-Seeking Behavior in Rats

Frontiers in Pharmacology, 2021
Epigenetic modifications such as DNA methylation play important roles in regulating gene expression and may mediate neuroplasticity and lead to drug-induced aberrant behaviors.
Qingxiao Hong, Qingxiao Hong, Wenjin Xu, Wenjin Xu, Zi Lin, Jing Liu, Weisheng Chen, Weisheng Chen, Huaqiang Zhu, Huaqiang Zhu, Miaojun Lai, Miaojun Lai, Dingding Zhuang, Dingding Zhuang, Zemin Xu, Zemin Xu, Dan Fu, Dan Fu, Wenhua Zhou, Wenhua Zhou, Huifen Liu, Huifen Liu   +21 more
doaj   +1 more source

Controlled Movement of Soft Actuators using Multi‐Responsive Microgel Arrays and Microcirculatory Systems

Advanced Functional Materials, EarlyView.
Microscale hydrogels (microgels) feature improved mass transport characteristics supportive of fast actuation and chemical tunability amenable to programmed stimuli response. A unique soft actuator architecture is realized by encapsulating microgels in soft microcirculatory systems which enable the convenient delivery of liquid stimuli for powering and
Nengjian Huang, Brennan P. Watts, Stephen A. Morin   +2 more
wiley   +1 more source

Associations of Menstrual Cycle Regularity and Length With Cardiovascular Diseases: A Prospective Study From UK Biobank

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background The association between menstrual cycle characteristics and cardiovascular outcomes remains unclear. This study was undertaken to evaluate whether menstrual cycle regularity and length throughout the life course are associated with ...
Chensihan Huang, Bingquan Lin, Youwen Yuan, Kangli Li, Bingyan Xu, Peizhen Zhang, Xueyun Wei, Weiwei Wang, Wenhui Liu, Yajuan Deng, Deying Liu, Jiayang Lin, Yan Huang, Huijie Zhang   +13 more
doaj   +1 more source

Synergistic All‐in‐One Electroceutical Platform Utilizing a Plasma–Photodynamic Hybrid Approach for Enhanced Wound Healing

Advanced Functional Materials, EarlyView.
A flexible hybrid patch integrating a robust cold atmospheric plasma (CAP) system with a high‐power, ultrathin bio‐OLED was developed to enable synergistic wound healing. This multimodal therapy, combining plasma and photodynamic treatment, enhanced angiogenesis, cell proliferation, and collagen deposition, demonstrating superior in vivo efficacy and ...
Jun‐Yeop Song, Hyun Cheol Bang, Young Hyun Son, Dae‐In Ha, Eun‐Ju Hong, Sun‐Woo Lee, Jeongsook Kim, Doyeong Kim, Sang‐Min Park, Kyu Pil Lee, Hyo‐Jung Kwon, Jeong Hyun Kwon   +11 more
wiley   +1 more source

Exosomes Derived From Pericytes Improve Microcirculation and Protect Blood–Spinal Cord Barrier After Spinal Cord Injury in Mice

Frontiers in Neuroscience, 2019
Spinal cord injury (SCI) often leads to severe and permanent paralysis and places a heavy burden on individuals, families, and society. Until now, the therapy of SCI is still a big challenge for the researchers. Transplantation of mesenchymal stem cells (
Xiaochen Yuan, Qingbin Wu, Peng Wang, Yingli Jing, Haijiang Yao, Yinshan Tang, Zhigang Li, Honggang Zhang, Ruijuan Xiu   +8 more
doaj   +1 more source