Results 41 to 50 of about 155,517 (332)

Multiscale modelling of fluid and solute transport in soft tissues and microvessels [PDF]

, 2010
This study focuses on the movement of particles and extracellular fluid in soft tissues and microvessels. It analyzes modeling applications in biological and physiological fluids at a range of different length scales: from between a few tens to several ...
Lu, Yiling, Wang, Wen
core   +2 more sources

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

Hepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang, Dan Wan, Mengchen Zhu, Guihu Wang, Xurui Zhang, Na Huang, Jian Zhang, Chongyu Zhang, Qi Shang, Chen Zhang, Xi Liu, Fanfan Liang, Chunyan Zhang, Guangyao Kong, Jing Geng, Libo Yao, Shemin Lu, Yongyan Chen, Zongfang Li   +18 more
wiley   +1 more source

Role of GABRD Gene Methylation in the Nucleus Accumbens in Heroin-Seeking Behavior in Rats

Frontiers in Pharmacology, 2021
Epigenetic modifications such as DNA methylation play important roles in regulating gene expression and may mediate neuroplasticity and lead to drug-induced aberrant behaviors.
Qingxiao Hong, Qingxiao Hong, Wenjin Xu, Wenjin Xu, Zi Lin, Jing Liu, Weisheng Chen, Weisheng Chen, Huaqiang Zhu, Huaqiang Zhu, Miaojun Lai, Miaojun Lai, Dingding Zhuang, Dingding Zhuang, Zemin Xu, Zemin Xu, Dan Fu, Dan Fu, Wenhua Zhou, Wenhua Zhou, Huifen Liu, Huifen Liu   +21 more
doaj   +1 more source

Murray's law revisited: Qu\'emada's fluid model and fractal trees [PDF]

, 2015
In 1926, Murray proposed the first law for the optimal design of blood vessels. He minimized the power dissipation arising from the trade-off between fluid circulation and blood maintenance.
Mauroy, Benjamin, Moreau, Baptiste
core   +3 more sources

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

Accessing depth-resolved high spatial frequency content from the optical coherence tomography signal

Scientific Reports, 2021
Optical coherence tomography (OCT) is a rapidly evolving technology with a broad range of applications, including biomedical imaging and diagnosis. Conventional intensity-based OCT provides depth-resolved imaging with a typical resolution and sensitivity
Sergey Alexandrov, Anand Arangath, Yi Zhou, Mary Murphy, Niamh Duffy, Kai Neuhaus, Georgina Shaw, Ryan McAuley, Martin Leahy   +8 more
doaj   +1 more source

Comparative study of the effects of cigarette smoke versus next generation tobacco and nicotine product extracts on endothelial function

Redox Biology, 2021
Tobacco smoking and hemodynamic forces are key stimuli for the development of endothelial dysfunction. As an alternative to smoking, next generation tobacco and nicotine products (NGP) are now widely used.
Sindy Giebe, Anja Hofmann, Melanie Brux, Frazer Lowe, Damien Breheny, Henning Morawietz, Coy Brunssen   +6 more
doaj   +1 more source

Improving vasculoprotective effects of MSCs in coronary microvessels – benefits of 3D culture, sub-populations and heparin

Frontiers in Immunology, 2023
IntroductionOpening occluded coronary arteries in patients with myocardial infarction (MI) damages the delicate coronary microvessels through a process called myocardial ischaemia-reperfusion injury.
Kobkaew Bumroongthai, Dean P. J. Kavanagh, Paul Genever, Neena Kalia   +3 more
doaj   +1 more source

The XIIIth Banff Conference on Allograft Pathology: The Banff 2015 Heart Meeting Report: Improving Antibody-Mediated Rejection Diagnostics: Strengths, Unmet Needs, and Future Directions. [PDF]

, 2017
The 13th Banff Conference on Allograft Pathology was held in Vancouver, British Columbia, Canada from October 5 to 10, 2015. The cardiac session was devoted to current diagnostic issues in heart transplantation with a focus on antibody-mediated rejection
Angelini, A, Berry, GJ, Bruneval, P, Dragun, D, Duong Van Huyen, JP, Fedrigo, M, Haas, M, Loupy, A, Mengel, M, Miller, D, Potena, L, Reed, EF, Reinsmoen, N, Revelo, P, Smith, RN, Tebutt, S, Thum, T, West, L, Zeevi, A   +18 more
core   +1 more source

Optical coherence tomography measurements of biological fluid flows with picolitre spatial localization [PDF]

, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014), Byers, R, Matcher, SJ   +2 more
core