Results 51 to 60 of about 197,951 (371)

Astaxanthin Attenuates Homocysteine-Induced Cardiotoxicity in Vitro and in Vivo by Inhibiting Mitochondrial Dysfunction and Oxidative Damage

Frontiers in Physiology, 2017
Homocysteine (Hcy) as an independent risk factor contributes to the occurrence and development of human cardiovascular diseases (CVD). Induction of oxidative stress and apoptosis was commonly accepted as the major mechanism in Hcy-induced cardiotoxicity.
Cun-dong Fan, Jing-yi Sun, Xiao-ting Fu, Ya-jun Hou, Yuan Li, Ming-feng Yang, Xiao-yan Fu, Bao-liang Sun, Bao-liang Sun   +8 more
doaj   +1 more source

Advanced glycation endproducts mediate chronic kidney injury with characteristic patterns in different stages

Frontiers in Physiology, 2022
Advanced glycation endproducts (AGEs) have been confirmed to play a causative role in the development of diabetic nephropathy (DN). In this study, we revealed that AGE-induced kidney injury with characteristic patterns in different stages and moesin ...
Xiaoxia Huang, Bingyu Li, Jiaqing Hu, Zhuanhua Liu, Dongping Li, Zhenfeng Chen, Hang Huang, Yanjia Chen, Yanjia Chen, Xiaohua Guo, Yun Cui, Yun Cui, Qiaobing Huang   +12 more
doaj   +1 more source

The role of the microcirculation in muscle function and plasticity

Journal of Muscle Research and Cell Motility, 2019
It is widely acknowledged that maintenance of muscle, size, strength and endurance is necessary for quality of life and the role that skeletal muscle microcirculation plays in muscle health is becoming increasingly clear.
P. Hendrickse, H. Degens
semanticscholar   +1 more source

Monitoring Microcirculation: Utility and Barriers – A Point-of-View Review

Vascular Health and Risk Management, 2020
Microcirculation is a particular organ of the cardiovascular system. The goal of this narrative review is a critical reappraisal of the present knowledge of microcirculation monitoring, mainly focused on the videomicroscopic evaluation of sublingual ...
A. Dubin, V. Kanoore Edul, J. F. Caminos Eguillor, G. Ferrara   +3 more
semanticscholar   +1 more source

Hemorheological Failure in the Pathology of Cardio-vascular Complications in Patients with Diabetic Foot Syndrome [PDF]

, 2016
The literature that includes the study of cardiovascular complications in patients with diabetic foot syndrome was analyzed. The topicality of this problem is caused by the steady growth of diabetes mellitus morbidity among people.
Кorobko, Е. (Еlina)
core   +2 more sources

The Regulatory Role of GBF1 on Osteoclast Activation Through EIF2a Mediated ER Stress and Novel Marker FAM129A Induction

Frontiers in Cell and Developmental Biology, 2021
Bone-resorbing activities of osteoclasts (OCs) are highly dependent on actin cytoskeleton remodeling, plasma membrane reorganization, and vesicle trafficking pathways, which are partially regulated by ARF-GTPases.
Cailing Wen, Yuheng Zhou, Yanting Xu, Huijing Tan, Caixia Pang, Haiqian Liu, Kaifei Liu, Linlin Wei, Hui Luo, Tian Qin, Chonghua He, Cuiling Liu, Chun Zhou   +12 more
doaj   +1 more source

Association of sublingual microcirculation parameters and endothelial glycocalyx dimensions in resuscitated sepsis

Critical Care, 2019
BackgroundThe endothelial glycocalyx (eGC) covers the luminal surface of the vascular endothelium and plays an important protective role in systemic inflammatory states and particularly in sepsis.
A. Rovas, L. Seidel, H. Vink, Timo Pohlkötter, H. Pavenstädt, C. Ertmer, Michael Hessler, P. Kümpers   +7 more
semanticscholar   +1 more source

Role of GABRD Gene Methylation in the Nucleus Accumbens in Heroin-Seeking Behavior in Rats

Frontiers in Pharmacology, 2021
Epigenetic modifications such as DNA methylation play important roles in regulating gene expression and may mediate neuroplasticity and lead to drug-induced aberrant behaviors.
Qingxiao Hong, Qingxiao Hong, Wenjin Xu, Wenjin Xu, Zi Lin, Jing Liu, Weisheng Chen, Weisheng Chen, Huaqiang Zhu, Huaqiang Zhu, Miaojun Lai, Miaojun Lai, Dingding Zhuang, Dingding Zhuang, Zemin Xu, Zemin Xu, Dan Fu, Dan Fu, Wenhua Zhou, Wenhua Zhou, Huifen Liu, Huifen Liu   +21 more
doaj   +1 more source

Protocol TOP-Study (tacrolimus organ perfusion): a prospective randomized multicenter trial to reduce ischemia reperfusion injury in transplantation of marginal liver grafts with an "ex vivo" tacrolimus perfusion [PDF]

, 2013
Background: Critical organ shortage results in the utilization of extended donor criteria (EDC) liver grafts. These marginal liver grafts are prone to increased ischemia reperfusion injury (IRI) which may contribute to deteriorated graft function and ...
Angele, Martin Kurt, Eder, Michael, Heise, Michael, Jauch, Karl-Walter, Nadalin, Silvio, Pascher, Andreas, Pratschke, Sebastian, Schemmer, Peter, Scherer, Marcus N., Ulrich, Frank, Wolters, Heiner, Wöhling, Dirk   +11 more
core   +1 more source

Bioinformatics exploration of potential common therapeutic targets for systemic and pulmonary arterial hypertension-induced myocardial hypertrophy

Acta Biochimica et Biophysica Sinica, 2023
Systemic and pulmonary arterial hypertension (PAH) can induce left and right ventricular hypertrophy, respectively, but common therapeutic targets for both left and right hypertrophy are limited.
Chen Lu, Li Mingjue, Shen Mengjia, Zhu Yingqi, Chen Kaitong, Huang Xiaoxia, Zheng Cankun, Wang Qiancheng, Lin Hairuo, Liao Wangjun, Bin Jianping, Ma Siyuan, Liao Yulin   +12 more
doaj   +1 more source