Results 181 to 190 of about 217,879 (236)

The Young's modulus of a microcrystalline cellulose

open access: yesCellulose, 2001
This research is concerned with an investigation into the determination of the micromechanical properties of a particulate form of cellulose, namely microcrystalline cellulose. Using the technique of Raman spectroscopy the shift in the 1095 cm-1 Raman band, characteristic of cellulose, with strain is monitored and compared to the deformation of natural
Eichhorn, SJ, Young, RJ
openaire   +4 more sources

The mechanical properties of compacts of microcrystalline cellulose and silicified microcrystalline cellulose

International Journal of Pharmaceutics, 2000
The mechanical properties of compacts of unlubricated microcrystalline cellulose and silicified microcrystalline cellulose were evaluated using the diametric tensile test. The results suggested that, under comparable testing conditions, compacts of silicified microcrystalline cellulose exhibited greater strength than those of microcrystalline cellulose.
Michael Tobyn   +2 more
exaly   +3 more sources

Physicochemical comparison between microcrystalline cellulose and silicified microcrystalline cellulose

International Journal of Pharmaceutics, 1998
Abstract Silicified microcrystalline cellulose (SMCC) has been compared with a standard grade of microcrystalline cellulose (MCC) using several physicochemical techniques in order to elucidate any chemical or polymorphic changes in the material that could be attributed to the silicification process.
Michael Tobyn   +2 more
exaly   +2 more sources

Functional performance of silicified microcrystalline cellulose versus microcrystalline cellulose: a case study

Drug Development and Industrial Pharmacy, 2009
During the development of a tablet dosage form of an investigational compound, R411, several aspects were identified as critical quality attributes that required optimization. The use of nonsolvent processing prevented the moisture-induced physical changes in the drug product but presented manufacturing challenges related to sticking during compression
Ahmad Aljaberi
exaly   +3 more sources

Adsorption of an Amine Drug onto Microcrystalline Cellulose and Silicified Microcrystalline Cellulose Samples

Drug Development and Industrial Pharmacy, 2003
The adsorption of a model amine drug (tacrine hydrochloride) from aqueous solution onto 21 microcrystalline cellulose (MCC) based samples has been investigated. The MCC source (manufacturer) affected adsorption. The adsorption appeared to be fully reversible.
Michael Tobyn   +2 more
exaly   +3 more sources

Directional Bonding in Compacted Microcrystalline Cellulose

Drug Development and Industrial Pharmacy, 2001
The mechanical properties of compacts of microcrystalline cellulose (MCC) and silicified microcrystalline cellulose (SMCC) were evaluated by tensile testing, diametric compression testing, and compression testing. For tensile and compression testing, cubic specimens were carefully machined from MCC and SMCC compacts, and the tensile and compression ...
John N Staniforth
exaly   +3 more sources

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