Results 191 to 200 of about 33,569 (240)

Physicochemical comparison between microcrystalline cellulose and silicified microcrystalline cellulose

International Journal of Pharmaceutics, 1998
Abstract Silicified microcrystalline cellulose (SMCC) has been compared with a standard grade of microcrystalline cellulose (MCC) using several physicochemical techniques in order to elucidate any chemical or polymorphic changes in the material that could be attributed to the silicification process.
Mike Tobyn, John N Staniforth, Stephen Edge   +2 more
exaly   +2 more sources

Functional performance of silicified microcrystalline cellulose versus microcrystalline cellulose: a case study

Drug Development and Industrial Pharmacy, 2009
During the development of a tablet dosage form of an investigational compound, R411, several aspects were identified as critical quality attributes that required optimization. The use of nonsolvent processing prevented the moisture-induced physical changes in the drug product but presented manufacturing challenges related to sticking during compression
Ahmad Aljaberi
exaly   +3 more sources

Adsorption of an Amine Drug onto Microcrystalline Cellulose and Silicified Microcrystalline Cellulose Samples

Drug Development and Industrial Pharmacy, 2003
The adsorption of a model amine drug (tacrine hydrochloride) from aqueous solution onto 21 microcrystalline cellulose (MCC) based samples has been investigated. The MCC source (manufacturer) affected adsorption. The adsorption appeared to be fully reversible.
D Fraser Steele, Stephen Edge, Mike Tobyn   +2 more
exaly   +3 more sources

The Young's modulus of a microcrystalline cellulose

Cellulose, 2001
This research is concerned with an investigation into the determination of the micromechanical properties of a particulate form of cellulose, namely microcrystalline cellulose. Using the technique of Raman spectroscopy the shift in the 1095 cm-1 Raman band, characteristic of cellulose, with strain is monitored and compared to the deformation of natural
Eichhorn, SJ, Young, RJ
openaire   +3 more sources

Microcrystalline cellulose in tableting

Journal of Pharmaceutical Sciences, 1966
The development of microcrystalline cellulose has made available to the pharmaceutical industry an extremely valuable tableting agent. It was found that tablets of plain microcrystalline cellulose will tend to soften and swell when exposed to humid conditions, but the effect is reversed upon the removal of increased humidities.
Dongyue Yu, Popescu, Carmen, Hoag, Stephen W   +2 more
openaire   +2 more sources

Coagulation of microcrystalline cellulose dispersions

Journal of Colloid and Interface Science, 1969
Abstract The coagulation effects on microcrystalline cellulose sols of simple ions, hydrolyzed metal ions, chelate complexes, and a series of alkylammonium chlorides differing in length of the hydrocarbon chain have been investigated. It was found that these sols are much more sensitive towards electrolytes than typical lyophilic colloids.
S, Kratohvil, G E, Janauer, E, Matijević   +2 more
openaire   +2 more sources

MICROCRYSTALLINE CELLULOSE STABILIZEDEMULSIONS

Journal of Dispersion Science and Technology, 1986
ABSTRACT Miorocrystalline cellulose stabilized emulsions (o/w) were evaluated by means of brightfield and polarized light microscopy, freeze-etch electron microscopy, droplet size analyses and rheologic measurements. These studies indicated that miorocrystalline cellulose (Avicel RC591 ) forms a network around emulsified oil droplets.
Kamlesh P. Oza, Sylvan G. Frank
openaire   +1 more source

True Density of Microcrystalline Cellulose

Journal of Pharmaceutical Sciences, 2005
Microcrystalline cellulose (MCC) exhibits unusual tableting properties, sometimes, inconsistent with its high plasticity. It is found that some of the unusual tableting properties of MCC can be explained in part by the use of inaccurate true density during tableting data analysis.
openaire   +2 more sources

Thin-layer chromatography on microcrystalline cellulose

Journal of Chromatography A, 1965
Abstract “Avirin”, or “Avicel”, a microcyrstalline form of cellulose, has been with success in this laboratory for thin-layer chromatography. The material is employed without a binder and has, in this laboratory, essentially completely displaced the papergram because its speed, quality of separation, and the ease with which preparative plates may be ...
M L, WOLFROM, D L, PATIN, R M, DELEDERKREMER   +2 more
openaire   +2 more sources

Microcrystalline cellulose replacement in cakes and biscuits

Journal of the American Dietetic Association, 1976
Sensory and physical characteristics of cakes and biscuits with up to 60 per cent of flour replaced, volume for volume, with microcrystalline cellulose were compared with those of the respective controls. High quality products were obtained at replacement levels of 40 and 20 per cent, respectively, in lean-formula cakes and in biscuits.
K D, Brys, M E, Zabik
openaire   +2 more sources