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Chromatography of microcystins
Analytica Chimica Acta, 1997Abstract This review deals with the analytical and preparative chromatography of microcystins and nodularins, cyclic peptide liver toxins and tumor promoters from cyanobacteria. The chemistry of the toxins, extraction from various matrices, separation on different stationary phases, and detection of intact and derivatized toxins are considered.
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Microcystin-LR Adsorption by Activated Carbon
Journal of Colloid and Interface Science, 2001We use a selection of wood-based and coconut-based activated carbons to investigate the factors controlling the removal of the hepatotoxin microcystin-LR (m-LR) from aqueous solutions. The wood carbons contain both micropores and mesopores. The coconut carbons contain micropores only.
Phillip, Pendleton +2 more
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Microcystin in Missouri reservoirs
Lake and Reservoir Management, 2009Abstract During summers (May–Aug) 2004–2006, 177 Missouri reservoirs were sampled monthly at open pelagic locations to assess regional patterns in microcystin concentration, frequency of occurrence over successive summer seasons and relations with environmental factors. Microcystin was detected in 58% of Missouri reservoirs and 23% of samples (n = 1402)
Jennifer L. Graham, John R. Jones
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Automated purification of microcystins
Journal of Chromatography A, 1996Abstract A simplified method for the concentration and purification of microcystins was developed. A 3-1 volume of cyanobacterial scum (equivalent to 124 g dry mass of cells) collected from Rutland and Water, Leicestershire, in 1989 was extracted in methanol and centrifuged and the supernatant was retained. This was diluted to ca.
Christine Edwards +3 more
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The biological functions of microcystins
Water ResearchMicrocystins are potent hepatotoxins predominantly produced by bloom-forming freshwater cyanobacteria (e.g., Microcystis, Planktothrix, Dolichospermum). Microcystin biosynthesis involves large multienzyme complexes and tailoring enzymes encoded by the mcy gene cluster. Mutation, recombination, and deletion events have shaped the mcy gene cluster in the
Nian Wei +4 more
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Trace analysis of microcystins
Phycologia, 1996Abstract It has recently become important to determine trace amounts of microcystins in complicated matrices such as water and biological samples, because they show potent hepatotoxicity and tumour-promoting activity on the liver. For development of an analytical method, it is essential to understand the physical, chemical and biological properties of ...
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Microcystin: Isolation by Supercritical Fluid Extraction
2005Huwei Liu, Bing Yu
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