Results 31 to 40 of about 34,690 (216)
Dexamethasone-Enhanced Microdialysis and Penetration Injury
Frontiers in Bioengineering and Biotechnology, 2020 Microdialysis probes, electrochemical microsensors, and neural prosthetics are often used for in vivo monitoring, but these are invasive devices that are implanted directly into brain tissue. Although the selectivity, sensitivity, and temporal resolution
Andrea Jaquins-Gerstl, Adrian C. Michael
doaj +1 more source
Microdialysis in CNS PKPD Research: Unraveling Unbound Concentrations
, 2012 The pharmacokinetic (PK) processes of drug movements between blood and tissues and the drug concentration profiles within a tissue over time can be described with the help of microdialysis sampling.
Hammarlund-Udenaes, Margareta, +1 more
core +1 more source
Application of Microdialysis in Clinical Pharmacology [PDF]
, 2006 Microdialysis has been developed during the last 25 years by several authors primarily to study brain function and changes in levels of endogenous compounds such as neurotransmitters or metabolites in different laboratory animals.
Opezzo, Javier +3 more
core +1 more source
Microdialysis in CNS PKPD research: Unraveling unbound concentrations
, 2013 With the help of microdialysis sampling, we can describe pharmacokinetic processes of drug movement between blood and tissues, and can describe concentration profiles within a tissue over time.
Hammarlund-Udenaes, Margareta,
core +1 more source
Acta OrthopaedicaBackground and purpose: The duration of antibiotic coverage in hand tissues during surgery is unknown. We investigated the time the free concentration of cefuroxime was above the minimal inhibitory concentration (fT>MIC) of 4 μg/mL in hand tissues after
Andrea René Jørgensen +5 more
doaj +1 more source
Indian Journal of Neurosurgery, 2017 Patients with traumatic brain injury (TBI) have variable outcomes subject to intracranial hypertension, ischemia, hypotension, and various biochemical alterations.
Deepak Kumar Gupta, Anna Teresa Mazzeo
doaj +1 more source
Advanced Science, EarlyView.MetaboSense is a first‐of‐its‐kind microfluidic platform enabling continuous, in‐line monitoring of glucose and lactate during ex vivo lung perfusion. Combining a quantum dot–mediated aptamer assay with mixing, depletion, and optofluidic detection modules, it achieves 60–s temporal resolution and shows strong agreement with standard blood gas analyzers,
Sanjana Srikant +14 more
wiley +1 more source
Brain microdialysis in neurobiology and neurochemistry
Фундаментальная и клиническая медицина, 2020 Microdialysis is a versatile and popular minimally invasive technique which enables sampling, collecting, and continuous measurement of small-molecular-weight substances in the extracellular fluid of virtually any tissue.
E. V. Kharitonova +4 more
doaj +1 more source
Advanced Science, EarlyView.Using a novel, aptamer‐based biosensor, here we have performed 20‐s‐resolved, in situ measurements of plasma‐free tryptophan in the jugular veins of live rats (blue). This unprecedented time‐resolution provides insights into the regulation of tryptophan metabolism in live, intact animals.
Yuyang Wu +7 more
wiley +1 more source
In Vivo Monitoring of Acetylcholine Release from Nerve Endings in Salivary Gland
Biology, 2021 A microdialysis technique was used to monitor acetylcholine levels in the local interstitial fluid in rat submandibular glands, with the aim of determining parasympathetic nerve activity in vivo.
Masanobu Yoshikawa, Mitsuru Kawaguchi
doaj +1 more source