Results 31 to 40 of about 58,170 (269)

Orexin-Corticotropin-Releasing Factor Receptor Heteromers in the Ventral Tegmental Area as Targets for Cocaine [PDF]

, 2015
Release of the neuropeptides corticotropin-releasing factor (CRF) and orexin-A in the ventral tegmental area (VTA) play an important role in stress-induced cocaine-seeking behavior.
Aguinaga, David, Cai, Ning-Sheng, Canela, Enric I, Casadó, Vicent, Cortés, Antonio, Ferré, Sergi, Hausch, Felix, Howell, Lesley A., Lluís, Carme, Mallol, Josefa, McCormick, Peter J., McDowell, Kimberly, Moreno, Estefanía, Moreno-Delgado, David, Navarro, Gemma, Quiroz, César, Rea, William, Sierakowiak, Adam   +17 more
core   +1 more source

Bedside interpretation of cerebral energy metabolism utilizing microdialysis in neurosurgical and general intensive care

Frontiers in Neurology, 2022
The microdialysis technique was initially developed for monitoring neurotransmitters in animals. In 1995 the technique was adopted to clinical use and bedside enzymatic analysis of glucose, pyruvate, lactate, glutamate and glycerol.
Carl-Henrik Nordström, Axel Forsse, Rasmus Peter Jakobsen, Simon Mölström, Troels Halfeldt Nielsen, Palle Toft, Urban Ungerstedt   +6 more
doaj   +1 more source

Ethane-beta-Sultam Modifies the Activation of the Innate Immune System Induced by Intermittent Ethanol Administration in Female Adolescent Rats [PDF]

, 2014
Intermittent ethanol abuse or ‘binge drinking’ during adolescence induces neuronal damage, which may be associated with cognitive dysfunction. To investigate the neurochemical processes involved, rats were administered either 1 g/kg or 2 g/kg ethanol in ...
Colivicchi, M.A., De Witte, Philippe, Della Corte, L., Dexter, David T., Hemmings, K., Lallemand, Frédéric, Nayak, K., Page, M.I., Pitard, A., Stefanini, C., Ward, Roberta J.   +10 more
core   +1 more source

Aging and aerobic fitness affect the contribution of noradrenergic sympathetic nerves to the rapid cutaneous vasodilator response to local heating [PDF]

, 2011
Sedentary aging results in a diminished rapid cutaneous vasodilator response to local heating. We investigated whether this diminished response was due to altered contributions of noradrenergic sympathetic nerves; assessing 1) the age-related decline and,
Alan D. Ruddock, Angus JA, Garry A. Tew, Gary J. Hodges, James Moss, John M. Saxton, Markos Klonizakis   +6 more
core   +1 more source

Local Chemical Gradients in a Mammalian Cortex Measured In Vivo With a Silicon Nanodialysis Mass Spectrometry Platform

Angewandte Chemie, EarlyView.
Fluorescence image of the coronal slice of mouse brain where multiple neurochemicals have been measured in vivo with a nanodialysis platform coupled to CE‐MS to reveal strong millimeter‐scale spatial chemical gradients. Formation and maintenance of such local chemical compartments in the otherwise diffusion‐homogeneous cortex indicates strong ...
Weihua Shi, Keyin Li, Yu Ding, Alex G. Armstrong, Jonathan V. Sweedler, Yurii Vlasov   +5 more
wiley   +2 more sources

Microdialysis in Rodents [PDF]

Current Protocols in Neuroscience, 2009
AbstractMicrodialysis is an in vivo sampling technique that permits the quantification of various substances (e.g., neurotransmitters, peptides, electrolytes) in blood and tissue. It is also used to infuse substances into the brain and spinal cord. This unit describes methods for the construction and stereotaxic implantation of microdialysis probes ...
Agustin, Zapata, Vladimir I, Chefer, Toni S, Shippenberg   +2 more
openaire   +2 more sources

Modeling the measurement bias in interstitial glucose concentrations derived from microdialysis in skeletal muscle

Physiological Reports, 2022
Muscle tissue utilizes glucose as a fuel during exercise and stores glucose in form of glycogen during rest. The associated glucose transport includes delivery of glucose from blood plasma into the interstitial space and subsequent, GLUT‐4 facilitated ...
Hugo Angleys, Leif Østergaard
doaj   +1 more source

Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease [PDF]

, 2017
Alterations of the dopaminergic (DAergic) system are frequently reported in Alzheimer’s disease (AD) patients and are commonly linked to cognitive and non-cognitive symptoms. However, the cause of DAergic system dysfunction in AD remains to be elucidated.
Aversa, D, Berretta, N, Cavallucci, V, Coccurello, R, Cordella, A, Cutuli, Debora, D'Amelio, M., De Bartolo, P, Dell'Acqua, Mc, Federici, M, Giacovazzo, G, Keller, F, Krashia, P, Latagliata, EMANUELE CLAUDIO, Marino, R, Mercuri, Nb, Nobili, A, Petrosini, Laura, PUGLISI ALLEGRA, Stefano, Rizzo, Fr, Sancandi, M, Viscomi, Mt   +21 more
core   +3 more sources

Dexamethasone-Enhanced Microdialysis and Penetration Injury

Frontiers in Bioengineering and Biotechnology, 2020
Microdialysis probes, electrochemical microsensors, and neural prosthetics are often used for in vivo monitoring, but these are invasive devices that are implanted directly into brain tissue. Although the selectivity, sensitivity, and temporal resolution
Andrea Jaquins-Gerstl, Adrian C. Michael
doaj   +1 more source

Overview of Microdialysis [PDF]

Current Protocols in Neuroscience, 1997
AbstractThe technique of microdialysis enables the monitoring of neurotransmitters and other molecules in the extracellular environment. This method has undergone several modifications and is now widely used for sampling and quantitating neurotransmitters, neuropeptides, and hormones in the brain and periphery.
T S, Shippenberg, A C, Thompson
openaire   +2 more sources