Results 21 to 30 of about 58,170 (269)

Use of long-term microdialysis subcutaneous glucose monitoring in the management of neonatal diabetes - A first case report [PDF]

open access: yes, 2006
In neonatal diabetes mellitus (NDM), a rare genetic disorder, insulin therapy is required but the management is difficult. Frequent blood glucose determinations are necessary in most cases. Microdialysis subcutaneous glucose monitoring (MSGM) is feasible
Andreas Holzinger   +13 more
core   +1 more source

High-Performance Bioinstrumentation for Real-Time Neuroelectrochemical Traumatic Brain Injury Monitoring [PDF]

open access: yes, 2016
Traumatic brain injury (TBI) has been identified as an important cause of death and severe disability in all age groups and particularly in children and young adults.
Boutelle, M   +6 more
core   +2 more sources

Targeted Perfusion Therapy in Spinal Cord Trauma. [PDF]

open access: yes, 2020
We review state-of-the-art monitoring techniques for acute, severe traumatic spinal cord injury (TSCI) to facilitate targeted perfusion of the injured cord rather than applying universal mean arterial pressure targets.
Papadopoulos, MC, Saadoun, S
core   +1 more source

Microdialysis

open access: yes, 2013
Peer ...
Austin J. Combest, William C. Zamboni
  +6 more sources

The unsuitability of implantable Doppler probes for the early detection of renal vascular complications - a porcine model for prevention of renal transplant loss. [PDF]

open access: yesPLoS ONE, 2017
Vascular occlusion is a rare, but serious complication after kidney transplantation often resulting in graft loss. We therefore aimed to develop an experimental porcine model for stepwise reduction of the renal venous blood flow and to compare an ...
Chris Amdisen   +3 more
doaj   +1 more source

Fluoxetine: a case history of its discovery and preclinical development [PDF]

open access: yes, 2014
Introduction: Depression is a multifactorial mood disorder with a high prevalence worldwide. Until now, treatments for depression have focused on the inhibition of monoaminergic reuptake sites, which augment the bioavailability of monoamines in the CNS ...
Bel N   +20 more
core   +2 more sources

mGluR5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a CB1 receptor mechanism. [PDF]

open access: yes, 2018
Metabotropic glutamate receptor 5 (mGluR5) antagonism inhibits cocaine self-administration and reinstatement of drug-seeking behavior. However, the cellular and molecular mechanisms underlying this action are poorly understood.
Bi, Guo-Hua   +9 more
core   +2 more sources

Evidence for Dysfunction of the Nigrostriatal Pathway in the R6/1 Line of Transgenic Huntington's Disease Mice

open access: yesNeurobiology of Disease, 2002
The present multidisciplinary study examined nigrostriatal dopamine and striatal amino acid transmission in the R6/1 line of transgenic Huntington's disease (HD) mice expressing exon 1 of the HD gene with 115 CAG repeats.
Å. Petersén   +6 more
doaj   +1 more source

Simultaneous blood and brain microdialysis in a free-moving mouse to test blood-brain barrier permeability of chemicals

open access: yesToxicology Reports, 2020
Neurotoxic chemicals that pass through the blood-brain barrier (BBB) can influence brain function. Efficient methods to test the permeability of the BBB to specific chemicals would facilitate identification of potentially neurotoxic agents.
Toyoshi Umezu   +3 more
doaj   +1 more source

Enhanced human tissue microdialysis using hydroxypropyl-ß-cyclodextrin as molecular carrier. [PDF]

open access: yesPLoS ONE, 2013
Microdialysis sampling of lipophilic molecules in human tissues is challenging because protein binding and adhesion to the membrane limit recovery.
Marcus May   +5 more
doaj   +1 more source

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