Results 41 to 50 of about 34,690 (216)
An Integrated Artificial Intelligence Framework for Nanomedicine Engineering
Advanced Science, EarlyView.This review outlines a closed‐loop AI ecosystem for nanomedicine engineering. By synergizing multimodal data harmonization, objective‐driven AI architectures, and automated high‐throughput validation, this “Design‐Make‐Test‐Analyze” (DMTA) workflow transforms traditional heuristic formulation into a predictive, self‐optimizing paradigm, accelerating ...
Meichen Dong +10 more
wiley +1 more source
A Review of Cutaneous Microdialysis of Inflammatory Dermatoses
Acta Dermato-Venereologica, 2019 Microdialysis is a minimally invasive technique to study metabolic, biochemical, and pharmacological events in tissue. Factors that influence microdialysate collection include molecular weight cutoff of the membrane, perfusion rate, perfusate viscosity ...
Helen Rea, Brian Kirby
doaj +1 more source
BMC Cancer, 2010 Background Mitomycin C is a chemotherapeutic agent used in the treatment of peritoneal surface malignancies, administered as hyperthermic intraperitoneal chemotherapy after cytoreductive surgery.
Sørensen Olaf +6 more
doaj +1 more source
Antibiotics, 2023 Implant-associated osteomyelitis is one of the most feared complications following orthopedic surgery. Although the risk is low, sufficient antibiotic protection of the implant surface is important.
Johanne Gade Lilleøre +8 more
doaj +1 more source
Advanced Science, EarlyView.A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan +14 more
wiley +1 more source
Myocardial metabolism and ischemia assessed by microdialysis. Clinical and experimental studies in cardiac surgery [PDF]
, 2006 Background: The available methods to study myocardial metabolism and ischemia show considerable limitations when employed during and after cardiac surgery. Microdialysis is a technique for continuous sampling of substances from the interstitium.
Mantovani, Vittorio
core +1 more source
Fluorescence Imaging of Microdialysis Sampling [PDF]
, 2014 Many biomolecules including proteolytic enzymes known as matrix metalloproteinases (MMPs) are released when a material, such as a microdialysis probe, is implanted in a living organism.
Haynie, Jordan Leigh
core +3 more sources
Autonomous AI‐Driven Design for Skin Product Formulations
Advanced Intelligent Discovery, EarlyView.This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang +5 more
wiley +1 more source
Leptin and fractalkine: novel subcutaneous cytokines in burn injury
Disease Models & Mechanisms, 2020 Burn injury is a pathology underpinned by progressive and aberrant inflammation. It is a major clinical challenge to survival and quality of life. Although the complex local and disseminating pathological processes of a burn injury ultimately stem from ...
Dominic Friston +7 more
doaj +1 more source
Pharmaceuticals, 2021 Glucose hypometabolism, mitochondrial dysfunction, and cholinergic deficits have been reported in early stages of Alzheimer’s disease (AD). Here, we examine these parameters in TgF344-AD rats, an Alzheimer model that carries amyloid precursor protein and
Christian Viel +5 more
doaj +1 more source