Results 11 to 20 of about 58,170 (269)

High Cefuroxime Concentrations and Long Elimination in an Orthopaedic Surgical Deadspace—A Microdialysis Porcine Study

Antibiotics, 2022
Deadspace is the tissue and bony defect in a surgical wound after closure. This space is presumably poorly perfused favouring bacterial proliferation and biofilm formation.
Sara Kousgaard Tøstesen, Maiken Stilling, Pelle Hanberg, Theis Muncholm Thillemann, Thomas Falstie-Jensen, Mikkel Tøttrup, Martin Knudsen, Emil Toft Petersen, Mats Bue   +8 more
doaj   +1 more source

Effects of tourniquet inflation on peri- and postoperative cefuroxime concentrations in bone and tissue

Acta Orthopaedica, 2021
Background and purpose — Tourniquet is widely used in orthopedic surgery to reduce intraoperative bleeding and improve visualization. We evaluated the effect of tourniquet application on peri- and postoperative cefuroxime concentrations in subcutaneous ...
Pelle Hanberg, Mats Bue, Jesper Kabel, Andrea René Jørgensen, Christian Jessen, Kjeld Søballe, Maiken Stilling   +6 more
doaj   +1 more source

Acute Spinal Cord Injury: Correlations and Causal Relations Between Intraspinal Pressure, Spinal Cord Perfusion Pressure, Lactate-to-Pyruvate Ratio, and Limb Power. [PDF]

, 2021
BACKGROUND/OBJECTIVE: We have recently developed monitoring from the injury site in patients with acute, severe traumatic spinal cord injuries to facilitate their management in the intensive care unit.
Hogg, FRA, Kearney, S, Papadopoulos, MC, Saadoun, S, Zoumprouli, A   +4 more
core   +1 more source

Technical notes on the placement of cerebral microdialysis: A single center experience

Frontiers in Neurology, 2023
BackgroundCerebral microdialysis enables monitoring of brain metabolism and can be an important part of multimodal monitoring strategies in a variety of brain injuries.
Joseph A. Falcone, Jefferson W. Chen
doaj   +1 more source

Comparison of Intravenous Microdialysis and Standard Plasma Sampling for Monitoring of Vancomycin and Meropenem Plasma Concentrations—An Experimental Porcine Study

Antibiotics, 2023
Microdialysis is a catheter-based method suitable for dynamic sampling of unbound antibiotic concentrations. Intravenous antibiotic concentration sampling by microdialysis has several advantages and may be a superior alternative to standard plasma ...
Johanne Gade Lilleøre, Sofus Vittrup, Sara Kousgaard Tøstesen, Pelle Hanberg, Maiken Stilling, Mats Bue   +5 more
doaj   +1 more source

Monitoring of patients with microdialysis following pancreaticoduodenectomy—the MINIMUM study: study protocol for a randomized controlled trial

Trials, 2021
Background Postoperative pancreatic fistula after pancreatoduodenectomy is a much-feared complication associated with substantial mortality and morbidity.
Espen Lindholm, Nil Ekiz, Tor Inge Tønnessen   +2 more
doaj   +1 more source

Effects of local hypothermia-rewarming on physiology, metabolism and inflammation of acutely injured human spinal cord. [PDF]

, 2020
In five patients with acute, severe thoracic traumatic spinal cord injuries (TSCIs), American spinal injuries association Impairment Scale (AIS) grades A-C, we induced cord hypothermia (33 °C) then rewarming (37 °C).
A Bricolo, A Mizuma, A Schubert, C Hochstim, DW Marion, GL Clifton, GV Varsos, HA Choi, I Phang, I Phang, JR Bethea, K Chatzipanteli, K Chatzipanteli, KL Carpenter, L Zhu, M Dididze, M Erecinska, MC Werndle, MC Werndle, MJ Gallagher, PE Batchelor, PJ Andrews, PJ Hutchinson, RR Hansebout, S Chen, S Saadoun, S Shibuya, SR Lewis, TP Lo Jr.   +28 more
core   +1 more source

Inflammatory proteins in infected bone tissue – An explorative porcine study

Bone Reports, 2020
Objective: To explore the in situ inflammatory proteins in the local extracellular fluid of infected bone tissue. Material and methods: Seven pigs went through a two-step surgery performing a traumatically implant-associated Staphylococcus aureus ...
Mats Bue, Natasja Leth Bergholt, Louise Kruse Jensen, Henrik Elvang Jensen, Kjeld Søballe, Maiken Stilling, Pelle Hanberg   +6 more
doaj   +1 more source

Methodological and analytical considerations for intra-operative microdialysis

Fluids and Barriers of the CNS, 2023
Background Microdialysis is a technique that can be utilized to sample the interstitial fluid of the central nervous system (CNS), including in primary malignant brain tumors known as gliomas.
Cecile Riviere-Cazaux, Karishma Rajani, Masum Rahman, Juhee Oh, Desmond A. Brown, Jaclyn F. White, Benjamin T. Himes, Ignacio Jusue-Torres, Moses Rodriguez, Arthur E. Warrington, Sani H. Kizilbash, William F. Elmquist, Terry C. Burns   +12 more
doaj   +1 more source

A rapid screening method to select microdialysis carriers for hydrophobic compounds.

PLoS ONE, 2021
Microdialysis is a minimally invasive sampling technique which is widely applied in many fields including clinical studies. This technique usually has limitation on sampling hydrophobic compounds as aqueous solutions are commonly used as the perfusates ...
Sin-Jie Wang, Hsiao-Ting Lu, Yu-Chao Wang, Hsin-Ying Huang, Chung-Shi Yang   +4 more
doaj   +1 more source