Results 111 to 120 of about 686 (148)
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Current Radiopharmaceuticalse, 2011
With the increasing availability of alpha emitters, targeted α-particle therapy has emerged as a solution of choice to treat haematological cancers and micrometastatic and minimal residual diseases. Alpha-particles are highly cytotoxic because of their high linear energy transfer (LET) and have a short range of a few cell diameters in tissue, assuring ...
Nicolas, Chouin, Manuel, Bardies
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With the increasing availability of alpha emitters, targeted α-particle therapy has emerged as a solution of choice to treat haematological cancers and micrometastatic and minimal residual diseases. Alpha-particles are highly cytotoxic because of their high linear energy transfer (LET) and have a short range of a few cell diameters in tissue, assuring ...
Nicolas, Chouin, Manuel, Bardies
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Microdosimetry and Thermoluminescence
Radiation Research, 1984The mechanism for production of light from a thermoluminescent phosphor requires the combination of a trapped electron and hole at a luminescent center. The kinetics is that of a second-order process. Accordingly one may expect a similarity in the formalism for describing thermoluminescent emission (TL) and the theory of dual radiation action in ...
K, Li, P, Kliauga, H H, Rossi
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Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2001
A review of solid state microdosimetry is presented with an emphasis on silicon-based devices. The historical foundations and basics of microdosimetry are briefly provided. Various methods of experimental regional microdosimetry are discussed to facilitate a comparison with the more recent development of silicon microdosimetry.
P D, Bradley, A B, Rosenfeld, M, Zaider
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A review of solid state microdosimetry is presented with an emphasis on silicon-based devices. The historical foundations and basics of microdosimetry are briefly provided. Various methods of experimental regional microdosimetry are discussed to facilitate a comparison with the more recent development of silicon microdosimetry.
P D, Bradley, A B, Rosenfeld, M, Zaider
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Health Physics, 1993
Microdosimetric aspects of tritium radiotoxicity are discussed. The level of coincidence of tritium locations and of radiation-sensitive sites does not appear to be decisive for relative effectiveness of tritium exposures. The actual target structure and dimensions seem to be of more importance.
K, Morstin +4 more
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Microdosimetric aspects of tritium radiotoxicity are discussed. The level of coincidence of tritium locations and of radiation-sensitive sites does not appear to be decisive for relative effectiveness of tritium exposures. The actual target structure and dimensions seem to be of more importance.
K, Morstin +4 more
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Microdosimetry of Electron Microbeams
Radiation Research, 2004Track structures of 25, 50 and 80 keV primary electrons, simulated by the detailed-history Monte Carlo method, were analyzed for the frequency distributions of energy deposited in spheres with a diameter of 1 microm, placed in a cylindrically symmetrical array around the projected initial direction of the primary electron.
J H, Miller +4 more
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Microdosimetry of low-energy electrons
International Journal of Radiation Biology, 2012To investigate differences in energy depositions and microdosimetric parameters of low-energy electrons in liquid and gaseous water using Monte Carlo track structure simulations.KURBUC-liq (Kyushu University and Radiobiology Unit Code for liquid water) was used for simulating electron tracks in liquid water.
Thiansin, Liamsuwan +3 more
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Microdosimetry in Radioimmunotherapy
Radiation Protection Dosimetry, 1990Abstract Antibodies are rapidly being developed which target radionuclides to tumour tissue. The MIRD formulation to calculate absorbed dose from internal emitters has limitations in radiation targeted therapy because of the heterogeneity of antibody distribution through the tumour.
J.L. Humm, L.M. Chin, L. Cobb, R. Begent
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Radiation Protection Dosimetry, 1999
Microdosimetry deals with the problem of identifying radiosensitive targets and obtaining the probability of energy deposition therein. Models of radiation action (biological or otherwise) may then be used to convert this information into observable quantities.
M. Zaider, M.J. Bardash, J. Ladik
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Microdosimetry deals with the problem of identifying radiosensitive targets and obtaining the probability of energy deposition therein. Models of radiation action (biological or otherwise) may then be used to convert this information into observable quantities.
M. Zaider, M.J. Bardash, J. Ladik
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Microdosimetry of Alpha-irradiated Lung
Health Physics, 1984Measurements have been made on the fractions of tissue affected and distributions of energy deposited when rat and human lung are irradiated by alpha particles. Thin sections of alveolar tissue were examined in an image analyser and an imaginary 239PuO2 particle was placed in an alveolar sac.
J A, Simmons, S R, Richards
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Microdosimetry of Internal Sources
Radiation Research, 1977ROESCH, W. C. Microdosimetry of Internal Sources. Radiat. Res. 70, 494-510 (1977). Microdosimetry has been limited to irradiations characterized by uniform probabilities of charged-particle production. New methods are presented here for dealing with particles emitted by radionuclides embedded in the irradiated medium; these particles seldom emerge ...
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