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The Significant Role of the Microfilament System in Tumors [PDF]
Frontiers in Oncology, 2021 Actin is the structural protein of microfilaments, and it usually exists in two forms: monomer and polymer. Among them, monomer actin is a spherical molecule composed of a polypeptide chain, also known as spherical actin.
Yanhong Zhou
exaly +6 more sources
Multisynchrony in active microfilaments [PDF]
Physical Review Letters, 2020 Biological microfilaments exhibit a variety of synchronization modes. Recent experiments observed that a pair of isolated eukaryotic flagella, coupled solely via the fluid medium, display synchrony at nontrivial phase-lags in addition to in-phase and anti-phase synchrony.
Yi Man, Eva Kanso
arxiv +5 more sources
Research progress on the roles of actin-depolymerizing factor in plant stress responses [PDF]
Frontiers in Plant Science, 2023 Actin-depolymerizing factors (ADFs) are highly conserved small-molecule actin-binding proteins found throughout eukaryotic cells. In land plants, ADFs form a small gene family that displays functional redundancy despite variations among its individual ...
Yongwang Sun +8 more
doaj +2 more sources
Cytoplasmic Streaming in Plant Cells Emerges Naturally by Microfilament Self-Organization [PDF]
Proc. Natl. Acad. Sci. U.S.A. 110 (35), 14132-14137 (2013), 2013 Many cells exhibit large-scale active circulation of their entire fluid contents, a process termed cytoplasmic streaming. This phenomenon is particularly prevalent in plant cells, often presenting strikingly regimented flow patterns. The driving mechanism in such cells is known: myosin-coated organelles entrain cytoplasm as they process along actin ...
Goldstein, Raymond E. +1 more
arxiv +3 more sources
Bistability in the synchronization of actuated microfilaments [PDF]
Journal of Fluid Mechanics, 2017 Cilia and flagella are essential building blocks for biological fluid transport and locomotion at the micron scale. They often beat in synchrony and may transition between different synchronization modes in the same cell type. Here, we investigate the behavior of elastic microfilaments, protruding from a surface and driven at their base by a ...
Hanliang Guo +3 more
arxiv +6 more sources
MICROFILAMENTS IN EPIDERMAL CANCER CELLS [PDF]
The Journal of Cell Biology, 1974 The occurrence and structure of microfilaments in epidermal cancers induced in mice by treatment with 3,4-benzpyrene were investigated with the electron microscope. With malignant change, pleomorphic, undifferentiated cells with a cortical zone of microfilaments became increasingly abundant.
Harry L. Malech, Thomas L. Lentz
openalex +3 more sources
Frontiers in Pharmacology, 2020 Microcystin-leucine arginine (MC-LR) is a potent tumor initiator that can induce malignant cell transformation. Cellular mechanical characteristics are pivotal parameters that are closely related to cell invasion.
Guihua Wang, Fuqiang Tian, Guohui Wang
exaly +3 more sources
Actin Microfilament Mediates Osteoblast Cbfa1 Responsiveness to BMP2 under Simulated Microgravity [PDF]
PLoS ONE, 2013 Microgravity decreases osteoblastic activity, induces actin microfilament disruption and inhibits the responsiveness of osteoblast to cytokines, but the mechanisms remains enigmatic.
Zhongquan Dai
exaly +2 more sources
Extracellular AMP Inhibits Pollen Tube Growth in Picea meyeri via Disrupted Calcium Gradient and Disorganized Microfilaments [PDF]
PlantsAdenosine monophosphate (AMP) is a hydrolysis product of adenosine triphosphate (ATP) and adenosine diphosphate (ADP). In mammalian cells, extracellular AMP functions as a signaling molecule by binding to adenosine A1 receptors, thereby activating ...
Junhui Zhou +4 more
doaj +2 more sources
Topological phonon modes in filamentous structures [PDF]
Phys. Rev. E 83, 021913 (2011), 2010 Topological phonon modes are robust vibrations localized at the edges of special structures. Their existence is determined by the bulk properties of the structures and, as such, the topological phonon modes are stable to changes occurring at the edges. The first class of topological phonons was recently found in 2-dimensional structures similar to that
D. J. Gordon +5 more
arxiv +3 more sources