Results 271 to 280 of about 358,908 (302)
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CNS & Neurological Disorders - Drug Targets, 2011
Microglia, the tissue macrophages of the brain, have under healthy conditions a resting phenotype that is characterized by a ramified morphology. With their fine processes microglia are continuously scanning their environment. Upon any homeostatic disturbance microglia rapidly change their phenotype and contribute to processes including inflammation ...
Olah, M+3 more
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Microglia, the tissue macrophages of the brain, have under healthy conditions a resting phenotype that is characterized by a ramified morphology. With their fine processes microglia are continuously scanning their environment. Upon any homeostatic disturbance microglia rapidly change their phenotype and contribute to processes including inflammation ...
Olah, M+3 more
openaire +3 more sources
Microglial cells are the most receptive cells in the central nervous system (CNS), expressing several classes of receptors reflecting their immune heritage and newly acquired neural specialisation. Microglia possess, depending on the particular context, receptors to neurotransmitters and neuromodulators as well as immunocompetent receptors.
Augusto-Oliveira, Marcus+2 more
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Augusto-Oliveira, Marcus+2 more
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Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
Nature Reviews Neuroscience, 2007M. Block, L. Zecca, Jau-Shyong Hong
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Microglia: a sensor for pathological events in the CNS
Trends in Neurosciences, 1996G. Kreutzberg
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Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
Science, 2011R. Paolicelli+11 more
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Microglia: active sensor and versatile effector cells in the normal and pathologic brain
Nature Neuroscience, 2007U. Hanisch, H. Kettenmann
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Myeloid cells are fundamental constituents of the brain tumor microenvironment. In this chapter, we describe the state-of-the-art knowledge on the role of microglial cells in the cross-talk with the most common and aggressive brain tumor, glioblastoma. We report in vitro and in vivo studies related to glioblastoma patients and glioma models to outline ...
Stefano, Garofalo+2 more
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Stefano, Garofalo+2 more
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Microglial cells are unique tissue-resident macrophages located in the parenchyma of the central nervous system (CNS). A recent comparative transcriptional study on microglia across more than 20 species from leach across chicken and many more up to humans revealed multiple conserved features.
Elena, Guffart, Marco, Prinz
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Elena, Guffart, Marco, Prinz
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Microglia: Immune and non-immune functions.
Immunity, 2021K. Borst, A. Dumas, M. Prinz
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