Results 271 to 280 of about 358,908 (302)

Microglia Phenotype Diversity

CNS & Neurological Disorders - Drug Targets, 2011
Microglia, the tissue macrophages of the brain, have under healthy conditions a resting phenotype that is characterized by a ramified morphology. With their fine processes microglia are continuously scanning their environment. Upon any homeostatic disturbance microglia rapidly change their phenotype and contribute to processes including inflammation ...
Olah, M, Biber, K, VINET, JONATHAN, Boddeke, H. W. G. M.   +3 more
openaire   +3 more sources

Receptors on Microglia

Microglial cells are the most receptive cells in the central nervous system (CNS), expressing several classes of receptors reflecting their immune heritage and newly acquired neural specialisation. Microglia possess, depending on the particular context, receptors to neurotransmitters and neuromodulators as well as immunocompetent receptors.
Augusto-Oliveira, Marcus, Tremblay, Marie Ève, Verkhratsky, Alexei   +2 more
openaire   +3 more sources

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

Nature Reviews Neuroscience, 2007
M. Block, L. Zecca, Jau-Shyong Hong
semanticscholar   +1 more source

Microglia: a sensor for pathological events in the CNS

Trends in Neurosciences, 1996
G. Kreutzberg
semanticscholar   +1 more source

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

Science, 2011
R. Paolicelli, G. Bolasco, F. Pagani, L. Maggi, M. Scianni, P. Panzanelli, M. Giustetto, Tiago A. Ferreira, Eva Guiducci, L. Dumas, D. Ragozzino, C. Gross   +11 more
semanticscholar   +1 more source

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

Nature Neuroscience, 2007
U. Hanisch, H. Kettenmann
semanticscholar   +1 more source

Microglia in Glioma

Myeloid cells are fundamental constituents of the brain tumor microenvironment. In this chapter, we describe the state-of-the-art knowledge on the role of microglial cells in the cross-talk with the most common and aggressive brain tumor, glioblastoma. We report in vitro and in vivo studies related to glioblastoma patients and glioma models to outline ...
Stefano, Garofalo, Giuseppina, D'Alessandro, Cristina, Limatola   +2 more
openaire   +2 more sources

Evolution of Microglia

Microglial cells are unique tissue-resident macrophages located in the parenchyma of the central nervous system (CNS). A recent comparative transcriptional study on microglia across more than 20 species from leach across chicken and many more up to humans revealed multiple conserved features.
Elena, Guffart, Marco, Prinz
openaire   +2 more sources

Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine

Nature Neuroscience, 2022
Omar S. Mossad, Bérénice Batut, B. Yilmaz, N. Dokalis, Charlotte Mezö, Elisa Nent, Lara Susann Nabavi, Melanie Mayer, Feres José Mocayar Marón, Joerg M. Buescher, M. G. de Agüero, A. Szalay, T. Lämmermann, A. Macpherson, S. C. Ganal-Vonarburg, R. Backofen, Daniel Erny, M. Prinz, T. Blank   +18 more
semanticscholar   +1 more source

Microglia: Immune and non-immune functions.

Immunity, 2021
K. Borst, A. Dumas, M. Prinz
semanticscholar   +1 more source