Pituitary Adenylate-Cyclase Activating Polypeptide Regulates Hunger- and Palatability-Induced Binge Eating [PDF]
Frontiers in Neuroscience, 2016 While pituitary adenylate cyclase activating polypeptide (PACAP) signaling in the hypothalamic ventromedial nuclei (VMN) has been shown to regulate feeding, a challenge in unmasking a role for this peptide in obesity is that excess feeding can involve ...
Matthew M. Hurley +10 more
doaj +3 more sources
Poly‑D,L‑lactic acid (PDLLA) scalp microinjection protocol with optional light microneedling priming for non‑scarring alopecia: A prospective pilot case series [PDF]
JPRAS OpenBackground: PDLLA demonstrates angiogenic and regenerative properties that may support hair regrowth by enhancing perifollicular perfusion. Objective: To evaluate clinical improvement after PDLLA scalp microinjection in 20 patients using standardized ...
Olena Sydorchuk +7 more
doaj +2 more sources
The Kir channel in the nucleus tractus solitarius integrates the chemosensory system with REM sleep executive machinery for homeostatic balance [PDF]
Scientific ReportsThe locus coeruleus (LC), nucleus tractus solitarius (NTS), and retrotrapezoid nucleus (RTN) are critical chemosensory regions in the brainstem. In the LC, acid-sensing ion channels and proton pumps serve as H+ sensors and facilitate the transition from ...
Fayaz A. Mir, Sushil K. Jha
doaj +2 more sources
Protocol for microinjection of rapamycin into the zebrafish habenula [PDF]
STAR ProtocolsSummary: Mechanistic target of rapamycin complex 1 (mTorC1) activity plays a crucial role in brain development. Here, we present an approach for rapamycin microinjection into the habenula of larval zebrafish to achieve localized inhibition of the mTorC1 ...
Olga Doszyn +2 more
doaj +2 more sources
“Usage a CRISPR/Cas9-based for obtaining knockouts of economically significant cattle genes” [PDF]
E3S Web of Conferences, 2023 An experimental work dealing with the gene modification using the Cas9 RNA-based editing system was performed. Point site-specific breakpoints in gDNA were introduced at the zygote stage by microinjection of spCas9 mRNA protein and guide RNAs into the ...
Bruter A. +5 more
doaj +1 more source
Effects of Injection Depth and Volume of Stabilized Hyaluronic Acid in Human Dermis on Skin Texture, Hydration, and Thickness [PDF]
Archives of Aesthetic Plastic Surgery, 2014 Background Stabilized hyaluronic acid (S-HA) is used for soft tissue augmentation and can also be used for dermal hydration. According to previous reports, the injection volume of each shot is more than 0.02 cc for dermal hydration.
Jongseo Kim
doaj +1 more source
Functionally selective signaling for morphine and fentanyl antinociception and tolerance mediated by the rat periaqueductal gray. [PDF]
PLoS ONE, 2014 Functionally selective signaling appears to contribute to the variability in mechanisms that underlie tolerance to the antinociceptive effects of opioids.
Michael M Morgan +2 more
doaj +1 more source
Advanced Biomedical Research, 2020 Background: The release of dopamine (DA) in the posterior ventral tegmental area (pVTA) plays an important role in cue-related learning, reward, and relapse.
Seyed Mostafa Ahmadian +2 more
doaj +1 more source
Pigment International, 2022 Background Melasma is a hypermelanotic disorder, which poses therapeutic challenge. Tranexamic acid (TA) and glutathione are novel therapies for the treatment of melasma.
Kanchan Kumawat +5 more
doaj +1 more source
Head-Mounted Display-Based Microscopic Imaging System with Customizable Field Size and Viewpoint
Sensors, 2020 In recent years, the use of microinjections has increased in life science and biotechnology fields; specific examples include artificial insemination and gene manipulation.
Tadayoshi Aoyama +3 more
doaj +1 more source