Results 111 to 120 of about 18,274 (287)

Arhgef1 Deletion Disrupts Early Cortical Neurogenesis via PAK1 Overactivation and Causes Motor Dysfunction in Adulthood

open access: yesAdvanced Science, EarlyView.
ARHGEF1 plays a pivotal role in both embryonic cortical neurogenesis and adult motor function. During early development, it governs genesis of deep‐layer cortical neurons by negatively regulating RAC1/CDC42‐PAK1‐Cofilin signaling. In adulthood, ARHGEF1 is important for the maintenance of neuronal morphology and activity in the motor cortex, ensuring ...
Liuren Li   +14 more
wiley   +1 more source

Behavioural topography in the striatum: differential effects of quinpirole and D-amphetamine microinjections.

open access: yes, 1998
Behavioural evidence has accumulated that supports the hypothesis that specific territories of the striatum contribute differentially to the control of motor behaviours.
Susan D. Iversen, Juan J. Canales
core   +1 more source

Bubbles Acting as Micro End‐Effectors for Dexterous Manipulation and Sensing in Aqueous Environment

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Inspired by bubbles, this article proposes a low‐cost method for multifunctional manipulation and sensing using microbubbles in aqueous environments. Bubbles are easily generated in situ, enabling the safe and adaptive handling of microobjects and sensing of microforces and surface textures.
Zichen Xu, Qingsong Xu
wiley   +1 more source

Protocol for microinjection of rapamycin into the zebrafish habenula

open access: yesSTAR Protocols
Summary: Mechanistic target of rapamycin complex 1 (mTorC1) activity plays a crucial role in brain development. Here, we present an approach for rapamycin microinjection into the habenula of larval zebrafish to achieve localized inhibition of the mTorC1 ...
Olga Doszyn   +2 more
doaj   +1 more source

Effect of microinjections of 5-hydroxytryptamine and adrenaline in central grey on pain responsiveness during acute food deprivation in conscious rats

open access: yes, 2000
237-241To study the effects of microinjections of 5 hydroxytryptamine and adrenaline in central grey on pain responsiveness during acute food deprivation, experiments were conducted in nine male rats. Microinjections of 5 HT (10 μg/μl) and adrenaline (
Premendran, J.   +4 more
core  

Effect of bilateral microinjections into the IC of crescent doses (0.3, 5, 10 and 15 nmol/100 nl) of the selective α2-adrenoceptor antagonist RX821002 on mean arterial pressure (MAP) and heart rate (HR) baseline.

open access: yes, 2014
Effect of bilateral microinjections into the IC of crescent doses (0.3, 5, 10 and 15 nmol/100 nl) of the selective α2-adrenoceptor antagonist RX821002 on mean arterial pressure (MAP) and heart rate (HR) baseline.
Fernando H. F. Alves (505579)   +3 more
core   +1 more source

Patient‐Mounted Neuro Optical Coherence Tomography for Targeted Minimally Invasive Micro‐Resolution Volumetric Imaging in Brain In Vivo

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu   +7 more
wiley   +1 more source

Increased food intake after opioid microinjections into nucleus accumbens and ventral tegmental area of rat.

open access: yes, 2016
The nucleus accumbens (ACC) and ventral tegmental area (VTA), two areas believed to subserve reinforcement and increases in locomotor activity produced by opioid microinjections, were examined for their involvement in opioid-produced changes in ingestive

core   +1 more source

Establishment of Humanized EFNB2/B3 Murine Models for Investigating Nipah Virus Pathogenesis

open access: yesAnimal Research and One Health, EarlyView.
ABSTRACT Nipah virus (NiV) is a zoonotic paramyxovirus classified as a WHO priority pathogen, which causes severe respiratory disease and encephalitis in humans with high mortality. Currently, no licensed vaccines or specific antiviral therapies are available.
Wei Dong   +6 more
wiley   +1 more source

Group data showing the effect of melanocortin receptor blockade in the PVN on ARCN responses.

open access: yes, 2013
A: In barodenervated rats, microinjections of NMDA (10 mM, 20 nl) into the ARCN before the blockade of MC 3/4 receptors in the ipsilateral PVN by SHU9119 (open bar) elicited increases in MAP (n = 5).
Tetsuya Kawabe (292023)   +2 more
core   +1 more source

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