Results 111 to 120 of about 17,415 (301)

Microinjections of L-MEN1 rescue excitatory nAChR expression in vitro.

open access: yes, 2014
All vertical (voltage) scale bars represent 20 mV. All horizontal (time) scale bars represent 2 s. (a) Single, postsynaptic LPeD1 neurons were cultured in CM+DMSO (vehicle control; n = 8 for U0126 experiment; n = 16 for nifedipine experiment) and impaled
Frank Visser (649731)   +4 more
core   +1 more source

From Cytoskeletal Remodeling to Oocyte Quality: The Emerging Role of Mechanics

open access: yesAdvanced Science, EarlyView.
Mechanical properties of the oocyte are increasingly recognized as critical determinants of meiotic success and developmental potential. How actomyosin remodeling controls oocyte mechanics, how these properties are altered in pathological conditions, and how they could serve as markers in reproductive medicine are examined.
Anastasia Shihabi   +3 more
wiley   +1 more source

Interaction between estradiol and 5-HT1A receptors in the median raphe nucleus on acquisition of aversive information and association to the context in ovariectomized rats

open access: yesNeurobiology of Stress, 2017
The median raphe nucleus (MRN) is related to stress resistance and defensive responses, a crucial source of serotonergic neurons that project to prosencephalic structures related to stress and anxiety.
Telma Gonçalves Carneiro Spera de Andrade   +4 more
doaj   +1 more source

Chronotropic and dromotropic responses to localized glutamate microinjections in the rat nucleus ambiguus

open access: yes, 2014
The cardioinhibitory effects of cardiac vagal motoneurons (CVMs) are mediated by activation of postganglionic neurons in the epicardial ganglia which have been shown to exert functionally selective effects on heart rate and atrioventricular conduction in
Ford, Timothy W.   +3 more
core   +1 more source

Bubbles Acting as Micro End‐Effectors for Dexterous Manipulation and Sensing in Aqueous Environment

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Inspired by bubbles, this article proposes a low‐cost method for multifunctional manipulation and sensing using microbubbles in aqueous environments. Bubbles are easily generated in situ, enabling the safe and adaptive handling of microobjects and sensing of microforces and surface textures.
Zichen Xu, Qingsong Xu
wiley   +1 more source

GABAB receptor-mediated mechanisms in the RVLM studied by microinjections of two GABAB receptor antagonists

open access: yes, 1994
The cardiovascular effects of microinjections of two gamma-aminobutyric acid (GABA) antagonists specifically acting on GABAB receptors, 2-hydroxy-saclofen (2-OH-S) and CGP-35348, into vasopressor sites of rostral ventrolateral medulla (RVLM) were ...
P. Ruggeri   +5 more
core   +1 more source

Patient‐Mounted Neuro Optical Coherence Tomography for Targeted Minimally Invasive Micro‐Resolution Volumetric Imaging in Brain In Vivo

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu   +7 more
wiley   +1 more source

Leptin-Mediated Sympathoexcitation in Obese Rats: Role for Neuron–Astrocyte Crosstalk in the Arcuate Nucleus

open access: yesFrontiers in Neuroscience, 2019
IntroductionAccumulated evidence indicates that obesity is associated with enhanced sympathetic activation. Hypothalamic leptin-mediated signaling may contribute to the exaggerated sympathoexcitation of obesity.
Xuefei Liu, Hong Zheng
doaj   +1 more source

REM sleep-like episodes of motoneuronal depression and respiratory rate increase are triggered by pontine carbachol microinjections inin situperfused rat brainstem preparation

open access: yes, 2011
Hypoglossal nerve activity (HNA) controls the position and movements of the tongue. In persons with compromised upper airway anatomy, sleep-related hypotonia of the tongue and other pharyngeal muscles causes increased upper airway resistance, or total ...
Kubin, Leszek   +9 more
core   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam   +4 more
wiley   +1 more source

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