Results 141 to 150 of about 17,415 (301)

Protocol to assess the impact of sperm RNA on mouse preimplantation embryos using microinjection

STAR Protocols
Summary: Zygotic microinjections show that sperm RNAs transmit non-genetically inherited phenotypes to offspring and influence embryonic development.
Grace S. Lee, Natalie A. Trigg, Colin C. Conine   +2 more
doaj   +1 more source

Effect of bilateral microinjections into the IC of crescent doses (0.3, 5, 10 and 15 nmol/100 nl) of the selective α₁-adrenoceptor antagonist WB4101 on mean arterial pressure (MAP) and heart rate (HR) baseline.

, 2014
Effect of bilateral microinjections into the IC of crescent doses (0.3, 5, 10 and 15 nmol/100 nl) of the selective α1-adrenoceptor antagonist WB4101 on mean arterial pressure (MAP) and heart rate (HR) baseline.
Fernando H. F. Alves (505579), Leonardo B. M. Resstel (346236), Fernando M. A. Corrêa (346235), Carlos C. Crestani (505580)   +3 more
core   +1 more source

Influence of microinjections of D,L-homocysteic acid into the Bötzinger complex area on the cough reflex in the cat.

, 2008
Microinjections of D,L-homocysteic acid (DLH) were used to test the hypothesis that neuronal activation within the Botzinger complex area can modify the spatiotemporal characteristics of the cough reflex in 17 spontaneously breathing pentobarbitone ...
C Wang, I Poliacek, L W Corrie, M J Rose, D C Bolser   +4 more
core  

Paternal Exposure to the Neonicotinoid Pesticide Clothianidin Alters Sperm MicroRNA Profiles in Mice and Intergenerationally Reduces Locomotor Activity in Male Offspring

Journal of Applied Toxicology, EarlyView.
ABSTRACT Accumulating evidence suggests that paternal environmental factors have epigenetic effects on sperm and influence offspring. Neonicotinoid pesticides (NNs), which are widely used around the world, are known to affect offspring phenotypes through maternal exposure in mice, but the effect of the paternal exposure remains unknown.
Makiko Ito, Tetsushi Hirano, Sarika Nunobiki, Ayano Yoshimoto, Yukako Hara, Yuya Ishida, Sakura Yonoichi, Youhei Mantani, Toshifumi Yokoyama, Yoshiaki Tabuchi, Yoshinori Ikenaka, Nobuhiko Hoshi   +11 more
wiley   +1 more source

Forebrain mechanisms of pain and analgesia : effects of local anaesthetic and NMDA antagonist microinjections on persistent pain

, 1996
This series of experiments examined the neural mechanisms of analgesia caused by local anaesthetic blockade or selective blockade of N-methyl- scD-aspartate (NMDA) receptors at sites in the rat forebrain.
McKenna, John E. (John Erwin)
core  

Progressive Cellularization of Blastoderm and Extraembryonic Tissue Formation in the Ant Camponotus floridanus

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Illustration of the process of cellularization in Camponotus floridanus (top row) compared to Drosophila melanogaster (bottom row). Progressive direct formation of differentiating blastoderm mode is depicted using hexagons that represent energids (without borders) and cells (with borders). Colors of nuclei represent different cell types.
Nihan Sultan Milat, Murat Pekmez, Ab. Matteen Rafiqi   +2 more
wiley   +1 more source

The Role of HUWE1 on Mouse Neural Cell Proliferation and Zebrafish Neurodevelopment

Medicine Bulletin, EarlyView.
ABSTRACT The HECT, UBA, and WWE domain‐containing E3 ubiquitin protein ligase 1 (HUWE1) gene is located on the X chromosome and has been implicated in neurodevelopmental disorders. However, the mechanisms by which HUWE1 dosage affects nervous system development remain poorly understood. In this study, we demonstrate that HUWE1 overexpression suppresses
Haojuan Wu, Gan Shen, Xueguang Zhang, Xiang Wang, Tiechao Ruan, Chuan Jiang, Yunchuan Tian, Xinyao Tang, Jun Ma, Wenming Xu, Ying Shen   +10 more
wiley   +1 more source

Effect of bilateral microinjections into the IC of crescent doses (0.3, 5, 10 and 15 nmol/100 nl) of the selective α₂-adrenoceptor antagonist RX821002 on mean arterial pressure (MAP) and heart rate (HR) baseline.

, 2014
Effect of bilateral microinjections into the IC of crescent doses (0.3, 5, 10 and 15 nmol/100 nl) of the selective α2-adrenoceptor antagonist RX821002 on mean arterial pressure (MAP) and heart rate (HR) baseline.
Fernando H. F. Alves (505579), Leonardo B. M. Resstel (346236), Fernando M. A. Corrêa (346235), Carlos C. Crestani (505580)   +3 more
core   +1 more source

Chitosan‐protected dsRNA increases efficacy against Helicoverpa armigera without compromising biosafety for pollinators

Pest Management Science, EarlyView.
Chitosan/tripolyphosphate/double‐stranded RNA (dsRNA) nanoparticles enhance RNA interference efficacy of orally delivered dsRNA against Helicoverpa armigera. Nanoparticles reduce the LC50 and do not cause deleterious effects or toxicity on beneficial insects.
Daniel DN Vasquez, Lays A Teixeira, Rangel F Alves, Raire Cavalcante, Leonardo LP Macedo, Carmen SS Pires, Luciano P Silva, Maria CM Silva, Feras M Afifi, Carolina V Morgante, Martin G Edwards, Angharad MR Gatehouse, Maria F Grossi‐de‐Sa   +12 more
wiley   +1 more source

HvarAKR1B1‐mediated tolerance in Hippodamia variegata: Deciphering the metabolic adaptation and fitness costs under prolonged starvation

Pest Management Science, EarlyView.
Starvation stress significantly affected the growth and development of Hippodamia variegata. Combined transcriptome and metabolome analysis and RNA interference verification revealed that HvarAKR1B1 may be involved in the response of Hippodamia variegata to starvation stress.
Bing‐mei Song, De‐qin Hu, Yuan Li, Wang‐quan Jiao, Xiao‐li Ma, Hong‐sheng Pan   +5 more
wiley   +1 more source