Results 161 to 170 of about 18,274 (287)

Methyl 4‐O‐Demethylbarbatate Destabilises HIF‐1α and Enhances Temozolomide Sensitivity in Glioma Cells

Cell Proliferation, EarlyView.
The lichen‐derived metabolite methyl 4‐O‐demethylbarbatate (Me‐4‐O‐DBA) suppresses glioma stemness, motility, and metabolic plasticity through inhibition of HIF‐1α signaling and synergistically enhances temozolomide activity, highlighting a potential strategy to target stemness‐driven therapeutic resistance in glioma.
Rui Zhou, Mücahit Varlı, Rundong Liu, Jieun Yu, Hyung‐Ho Ha, Jae‐Seoun Hur, Sang Kyum Kim, Hahyun Park, Hangun Kim   +8 more
wiley   +1 more source

Refractory Stasis Dermatitis Due to Chronic Venous Insufficiency With Psychosocial Worsening in 2 Septuagenarian Patients Treated With Hyaluronic Acid-Succinic Acid Intradermotherapy. [PDF]

Am J Case Rep
Zhao Q, Zambrano MP, Brito S, Bin BH, Ran Y, Leguina-Ruzzi A.   +5 more
europepmc   +1 more source

Amylin Receptor Signalling in the Laterodorsal Tegmental Nucleus Controls Food Intake Through Projections to the Ventral Tegmental Area

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background The role of amylin signalling in energy balance control has been understudied in calcitonin receptor (CTR) expressing nuclei such as the mesopontine laterodorsal tegmental nucleus (LDTg). Our lab has shown that LDTg amylin signalling reduces feeding and body weight, but the neuronal phenotype and downstream targets of LDTgCTR cells ...
Marcos J. Sanchez Navarro, Carlie Zhang, Samantha M. Fortin, Matthew R. Hayes   +3 more
wiley   +1 more source

Exploring the Effectiveness, Tolerability, and Safety of the Adjunctive Use of Microneedling With Tranexamic Acid in the Treatment of Melasma. [PDF]

J Cosmet Dermatol
Dhaliwal S, Dhanoa N, Rashid Z.
europepmc   +1 more source

Maternal factors from a parasitoid wasp mediate hyperparasitoid attraction to parasitized caterpillars

Ecological Entomology, EarlyView.
The parasitoid‐associated polydnavirus CgPDV, but not venom alone, significantly increases the attractiveness of Pieris brassicae caterpillars to the hyperparasitoid Baryscapus galactopus at close range. Naturally parasitized caterpillars elicit stronger hyperparasitoid attraction than any injection treatment, indicating that additional factors beyond ...
Yuhan Liu, Mitchel E. Bourne, Maximilien A. C. Adam, Sarah N. Kalisvaart, Erik H. Poelman, Nina Xiaoning Zhang   +5 more
wiley   +1 more source

BMAL1 in Anterior Cingulate Cortex Pyramidal Neurons Relieves Pulpitis‐Induced Nocturnal Pain

International Endodontic Journal, EarlyView.
ABSTRACT Aim Nocturnal exacerbation of pulpitis‐induced pain severely disrupts patients' sleep and quality of life, increasing emergency dental care burden. However, the exact mechanisms underlying nocturnal pain remain poorly understood, limiting the development of targeted analgesic strategies.
Yuting Bai, Jialin Si, Jing Zhang, Zhuo Yu, Meng Nian, Yundi Qiao, Xiaoke Wu, Jing Huang, Li‐an Wu   +8 more
wiley   +1 more source

Integration of laryngeal and cardiorespiratory control by the dorsomedial and perifornical hypothalamus in anaesthetised rats. [PDF]

Front Neurosci
Carrillo-Franco L, González-García M, Morales-Luque C, Rivera A, Gago B, Ponce-Velasco M, Dawid-Milner MS, López-González MV.   +7 more
europepmc   +1 more source

Patent landscape analysis of inventions based on plant genetic resources for food and agriculture and related digital sequence information

The Journal of World Intellectual Property, EarlyView.
Abstract This article provides an overview of the patent landscape in relation to PGRFA‐based inventions involving naturally occurring (“native”) traits and related Digital Sequence Information/Genetic Sequence Data (DSI/GSD). In particular, it focuses on the potential of patent claims to limit others' uses of PGRFA and related DSI/GSD on which the ...
Claudio Chiarolla, Michael Andreas Kock, Paul Oldham, Michael Halewood, Isabel López Noriega, Jasmine Kindness   +5 more
wiley   +1 more source

Improvement of radiation-induced skin fibrosis with hyaluronic acid injections. [PDF]

JAAD Case Rep
Blessmann-Gurk B, Borrelli MR, Prager W.
europepmc   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

The Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil, Justin Shane Hooper, Seol‐Hee Kim, Parmvir K. Bahia, Nika Pavelkova, Sanjay S. Nair, Teresa S. Darcey, Karina V. Lurye, Meghana Madaram, Jailene Fiallo, Stephen H. Hadley, Thomas E. Taylor‐Clark   +11 more
wiley   +1 more source