Results 171 to 180 of about 18,274 (287)

MCT1‐mediated bidirectional propionate transport across human placental syncytiotrophoblast layer: insights from a trophoblast stem cell‐derived barrier model

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Propionate in the fetal circulation is thought to originate from fermentation of dietary fibre by the maternal gut microbiota. However, the mechanism of transplacental transport has remained unclear. Here, we measured propionate permeability using a placental barrier model generated by differentiating human placental trophoblast ...
Toshiaki Tsuchitani   +8 more
wiley   +1 more source

3D nanoprinting of embryo microinjection needles with anti-clogging features. [PDF]

open access: yesMicrosyst Nanoeng
Sarker S   +9 more
europepmc   +1 more source

Electrophysiological properties of the dorsal motor nucleus of the vagus motoneurones controlling airway mucus secretion in rats

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Acidosis depolarises parasympathetic respiratory motoneurones in the dorsal motor nucleus of the vagus (DMV) and increases their firing frequency by reducing TWIK‐2 channel conductance. Acidosis also activates astrocytes, which further enhance neuronal excitability through NMDA receptor‐dependent glutamatergic signalling.
Daniel P. de Souza   +4 more
wiley   +1 more source

Red Fluorescent Labeling of Myelin by Membrane‐Targeted tdTomato in Transgenic Mouse Lines

open access: yesGlia, Volume 74, Issue 12, December 2026.
Transgenic mouse lines expressing membrane‐targeted tdTomato in myelin enable imaging of myelin in the red spectral range. Distinct expression patterns range from wide‐spread labeling to sparse single‐cell resolution, supporting diverse imaging applications.
Anja Reinert   +15 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, Volume 20, Issue 11, Page 2741-2763, November 2026.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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