Results 151 to 160 of about 51,233 (376)

Metabolic fate of drugs of abuse and new psychoactive substances: A pilot study on a novel workflow using a zebrafish embryo model combined with human microdosing

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg, Tanja M. Gampfer, Lea Wagmann, Philip Schippers, Jennifer Herrmann, Rolf Müller, Folker Westphal, Markus R. Meyer   +7 more
wiley   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Decondensation and Male Pronuclear Formation in Bovine Oocytes after Microinjection of Bovine Sperm Pretreated with Disulfide Bond Reducing Agents.

, 1996
Xiao Qiao Qian, Hiroshi Inagaki, Hiroshi Sasada, Shichiro Sugawara   +3 more
openalex   +2 more sources

Fate of Postacrosomal Perinuclear Theca Recognized by Monoclonal Antibody MN13 after Sperm Head Microinjection and Its Role in Oocyte Activation in Mice1 [PDF]

, 2003
Gaurishankar Manandhar, Kiyotaka Toshimori   +1 more
openalex   +1 more source

The influence of microinjection parameters on cell survival and procedure efficiency

, 2023
Joanna Hajduk, Konrad Szajna, Bartosz Lisowski, Zenon Rajfur   +3 more
openalex   +1 more source

Protein turnover downstream of the Nipbl/CRL4 axis contributes to abnormal development in zebrafish embryos

Developmental Dynamics, EarlyView.
Abstract Background Mutations in cohesins cause cohesinopathies such as Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS). Prior findings demonstrate that Esco2 (a cohesin activator) and Smc3 (a core cohesin subunit) regulate the CRL4 E3 ubiquitin ligase. SMC3 mutations, however, account for a small percentage of CdLS.
Annie C. Sanchez, Niusha Banoukh, Fiona Mensching, Robert V. Skibbens, M. Kathryn Iovine   +4 more
wiley   +1 more source

Microinjection of carbachol in the supramammillary region suppresses CA1 pyramidal cell synaptic excitability

, 2006
Fengli Jiang, Sanjay Khanna
openalex   +2 more sources

Microinjection based zebrafish embryo test for the detection of estrogenic substances in slurry based irrigation water and its combined application with yeast estrogen screen

, 2022
Zsolt Csenki, Eduárd Gubó, Edina Garai, Katalin Bakos, Dóra Kánainé Sipos, Erna Vásárhelyi, Béla Urbányi, Pál Szakál, Judit Plutzer   +8 more
openalex   +1 more source

Epilepsy surgery: From bench to the clinics

Epilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

Microinjection of Dynorphin into the Supraoptic and Paraventricular Nuclei Produces Antidiuretic Effects through Vasopressin Release

, 1993
Hiromi Tsushima, Mayumi Mori, Tomohiro Matsuda   +2 more
openalex   +1 more source