Results 171 to 180 of about 23,778 (281)

Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling

open access: yesCell Proliferation, EarlyView.
This work identifies Hcfc1 and Ogt as key regulators of zebrafish CNS regeneration through modulation of Hippo/Yap signalling. Loss of Hcfc1 or Ogt activity inhibition impairs regeneration, which is restored by Yap overexpression, revealing a new regulatory axis that enhances CNS regenerative capacity.
Priyanka P. Srivastava   +9 more
wiley   +1 more source

Phosphatase PPP1CC Regulates the First Lineage Segregation by GAS5 in Mouse Preimplantation Embryos

open access: yesCell Proliferation, EarlyView.
Subcortical GAS5 directs PPP1CC phosphatase spatiotemporal positioning during mouse morula‐blastocyst transition, controlling YAP dephosphorylation to drive first embryonic lineage specification. ABSTRACT The transcriptional effector of the Hippo signalling pathway, YAP, regulates the first lineage specification in mouse preimplantation embryos ...
Jianwu Wang   +10 more
wiley   +1 more source

A single injection of neuropeptide QRFP in the lateral hypothalamus decreased food intake. [PDF]

open access: yesJ Psychopharmacol
Zagorácz O   +11 more
europepmc   +1 more source

Reduced fecundity associated with Wolbachia infection in a Neotropical drosophilid Redução da fecundidade associada à infecção por Wolbachia em um drosofilídeo Neotropical

open access: yesEcological Entomology, EarlyView.
Using multiple infected and uninfected Drosophila sturtevanti lines, we investigated (i) the impact of Wolbachia on fecundity and (ii) its effects relative to antibiotic treatment. Based on over 1680 dissected ovaries, fecundity was similar between infected and uninfected flies.
Letícia Carlesso de Paula Sena   +4 more
wiley   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

open access: yesThe FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola   +11 more
wiley   +1 more source

Breeding 5.0: Artificial intelligence (AI)‐decoded germplasm for accelerated crop innovation

open access: yesJournal of Integrative Plant Biology, EarlyView.
ABSTRACT Crop breeding technologies are vital for global food security. While traditional methods have improved yield, stress tolerance, and nutrition, rising challenges such as climate instability, land loss, and pest pressure now demand new solutions.
Jiayi Fu   +4 more
wiley   +1 more source

Control of Blood Pressure Variability Across Behavioral States by Brainstem Adrenergic Neurons. [PDF]

open access: yesCirc Res
Souza GMPR   +6 more
europepmc   +1 more source

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