Results 191 to 200 of about 28,349 (334)

Analysis of the intracellular localization and assembly of Ro ribonucleoprotein particles by microinjection into Xenopus laevis oocytes. [PDF]

, 1994
F.H.M. Simons, Ger J.M. Pruijn, W J van Venrooij   +2 more
openalex   +1 more source

Exploring the roles of conserved context‐dependent cis‐regulatory elements (cdCREs) in multicellularity, human health and disease

The FEBS Journal, EarlyView.
Conserved context‐dependent cis‐regulatory elements act as a major reservoir of disease‐associated polymorphisms in the human genome and are also affected by epigenetic change. This ‘state‐of‐the‐art’ review explores the latest developments in studying these enigmatic elements and how the effects of disease‐associated polymorphisms and environmentally ...
Andrew McEwan, Alexander Rattray, Greg Hutchings, Elizabeth Hay, Chris Murgatroyd, Alasdair MacKenzie   +5 more
wiley   +1 more source

The role of the dorsomedial hypothalamus in the cardiogenic sympathetic reflex in the Sprague Dawley rat. [PDF]

Front Physiol
Zahner MR, Hillard KJ, Chandley MC.
europepmc   +1 more source

Inhibition of Thyrotropin-Stimulated DNA Synthesis by Microinjection of Inhibitors of Cellular Ras and Cyclic AMP-Dependent Protein Kinase [PDF]

, 1993
Erik Kupperman, Wen Wei, Judy L. Meinkoth   +2 more
openalex   +1 more source

High‐throughput screening identifies a previously undescribed checkpoint controlling mitotic progression in response to DNA damage

The FEBS Journal, EarlyView.
DNA damage can cause mitotic delay to allow DNA repair to occur. However, the mechanism underlying this is unclear. Here, we show that in response to cells entering mitosis with DNA damage, SOD1 restrains PP2a activity via oxidation of cysteine residues at the active site. This leads to a reduction in PP2a activity at the mitotic kinetochore, resulting
Nan Li, Rachel Gatenby, Thomas Walne, Caroline Daye, Steven Watson, Priya Lata, Stephen Brown, Ruth Thompson   +7 more
wiley   +1 more source

AMPA Receptor Within the Prelimbic Cortex Regulates Propofol-Induced Locomotor Sensitization. [PDF]

Addict Biol
Pan C, Mao X, Jiang Y, Jiang C, Qiu J, Zhang Y, Chen G, Xu M, Li J, Wu B.   +9 more
europepmc   +1 more source

Artifacts caused by cell microinjection.

, 1984
David S. Miller, Y T Lau, Samuel B. Horowitz   +2 more
openalex   +1 more source

Microinjection of villin into cultured cells induces rapid and long-lasting changes in cell morphology but does not inhibit cytokinesis, cell motility, or membrane ruffling. [PDF]

, 1990
Zsofia Franck, Matthew J. Footer, Anthony Bretscher   +2 more
openalex   +1 more source

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

The FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický, Sonja Lindfors, Saana Metso, Julia Koivula, Zoltan Szabo, Rasmus Valtonen, Mikko Tulppo, Johanna Magga, Samu Saarimäki, Sonja Bläuer, Ilkka Miinalainen, Risto Kerkelä, Petteri. T. Piepponen, Vootele Voikar, Juho Väänänen, Riikka Kivelä, Bhagwan Yadav, Hanna Lindgren, Pirkko Mattila, Fu‐Ping Zhang, Petra Sipilä, Reetta Hinttala, Satu Kuure   +22 more
wiley   +1 more source

Molecular and cellular targets of GABAergic anesthetics in the mesopontine tegmentum that enable pain-free surgery. [PDF]

Pain
Baron M, Vaso K, Ibraheem A, Minert A, Minert A, Devor M.   +5 more
europepmc   +1 more source