Results 201 to 210 of about 23,778 (281)

Altered Ventilation in Rats With Established Severe Monocrotaline-Induced Pulmonary Hypertension: The Role of the Dorsal Hypothalamus. [PDF]

Compr Physiol
Le Pape A, Guignabert C, Tu L, Mougenot N, Burban E, David D, Bottemanne H, Corruble E, Similowski T, Sevoz-Couche C.   +9 more
europepmc   +1 more source

Application of Intracellular Vesicles Surpass Extracellular Vesicles in Regenerative Repair of Inflammatory Bone Defects via the LAMA4‐Mediated YAP/TAZ Signalling

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Periodontitis‐induced inflammatory microenvironment compromises the function of periodontal ligament stem cells (PDLSCs) and significantly impedes the regeneration of periodontal tissues. Meanwhile, the clinical application of extracellular vesicles (EVs) is constrained by their low yield and high production costs.
Haotian Liu, Yu Wu, Qunyi Wang, Ting Zhang, Xin Tong, Fuhua Yan, Qian Zhang   +6 more
wiley   +1 more source

Consensus statement on mesotherapy for clinical and regulatory practice. [PDF]

Rheumatol Int
Mammucari M, Russo D, Maggiori E, Di Marzo R, Rossi M, Lugli M, Migliore A, Leone R, Koszela K, Bertinato L, Aloi TL, Bini F, Brugin E, Beltrami G, Scorcu M, Corrado B, Catizzone A, Cirfera V, Rocchi P, Colonna M, De Vito A, Finco G, Gori F, Marotto D, Natoli S, Sideli C, Varano M, Zurlo V, Anedda C, Antonaccio P, Antonelli A, Morselli FA, Beatini A, Bissi F, Boito B, Bruni M, Cacciatore F, Capeti L, Carusone A, Celani F, Coccetti B, Conte F, Cosmai D, Costumato A, Cremasco F, Crescenzo R, Cresta P, Dalmonte S, Gentile R, Ladiana N, Laurenza M, Presti CL, Lagreca N, Licheri AM, Marcolongo SP, Marcuccio F, Mascolo M, Mauriello V, Moccia E, Moretti CT, Muzi F, Notarrigo P, Perletto F, Pini A, Pistolesi E, Piombino L, Polistina C, Rana N, Ramponi V, Raso S, Rodofili C, Schirò P, Servili A, Somaschi M, Taccagna DM, Tomasell F, Tufaro G, Tumminelli L, Viglione G, Violo B, Vitali E, Antonaci L, Bertoni L, Baioccato V, Bifarini B, Carpenedo R, Chinè E, Ceniti S, Dorato D, Ferrari F, Fiorentini AG, Gallo A, Gallo R, Chiara G, Costanza G, Palermi S, Paolucci T, Preite U, Santini S, Savina MA, Scanu MP, Trocchi G, Troili F, Vecchiato M, Amore LA, Ciccotti RM, Tuzi A, Alama E, Canarecci S, Severoni S, Sozio MP, Varrassi G.   +111 more
europepmc   +1 more source

Autophagy‐Independent Function of ATG‐18 Is Essential for Gonadal Longevity in Caenorhabditis elegans

Aging Cell, Volume 25, Issue 4, April 2026.
Neuronal and intestinal ATG‐18 promote longevity conferred by germline removal in C. elegans via non‐autophagic functions. In the intestine, ATG‐18 regulates lifespan through its interaction with the gluconeogenic enzyme PCK‐2. ABSTRACT Autophagy, a highly conserved cellular degradation process, plays essential roles in various physiological processes ...
Tatsuya Shioda, Ittetsu Takahashi, Makoto Horikawa, Taiichi Osumi, Takayuki Shima, Akiyo Yamauchi, Kayo Nakamura, Taeko Sasaki, Tatsuya Kaminishi, Harunori Yoshikawa, Miyuki Sato, Hidetaka Kosako, Tamotsu Yoshimori, Shuhei Nakamura   +13 more
wiley   +1 more source

Molecular and cellular targets of GABAergic anesthetics in the mesopontine tegmentum that enable pain-free surgery. [PDF]

Pain
Baron M, Vaso K, Ibraheem A, Minert A, Minert A, Devor M.   +5 more
europepmc   +1 more source

RUVBL2 Regulates Microglia Metabolic Reprogramming to Mediate Stress Granules Aggregation Exacerbating Postoperative Delirium in Aged Mild Cognitive Impairment Rats

Aging Cell, Volume 25, Issue 4, April 2026.
RUVBL2 mediates stress granule aggregation by regulating microglial metabolic reprogramming, thereby exacerbating postoperative delirium in aged rats with mild cognitive impairment. ABSTRACT Postoperative delirium (POD) accelerates the transition from mild cognitive impairment (MCI) to Alzheimer's disease (AD) in elderly patients.
Lin Zhang, Zixuan Wang, Chenyi Yang, Xinyi Wang, Xing Liu, Haonan Zhang, Huan Liu, Huihui Liao, Jun Chen, Haiyun Wang   +9 more
wiley   +1 more source

Intracerebroventricular insulin injection acutely normalizes the augmented exercise pressor reflex in male rats with type 2 diabetes mellitus. [PDF]

J Physiol
Estrada JA, Ishizawa R, Kim HK, Fukazawa A, Hori A, Hotta N, Iwamoto GA, Smith SA, Vongpatanasin W, Mizuno M.   +9 more
europepmc   +1 more source

Sex Differences in the Effects of Etonogestrel on Respiratory Recovery in an In Vivo Rat Model of Central Chemoreflex Impairment

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Rhythmic breathing movements driven by the brainstem rely on chemosensory inputs to homeostatically adjust motor output to the prevailing metabolic demand. The central CO2 chemoreflex is a critical component of this neural circuitry, as defects in these sensors cause hypoventilation syndromes, which are typically difficult to manage ...
Silvia Cardani, Tara A. Janes, Ryaad Asif, Silvia Pagliardini   +3 more
wiley   +1 more source

CRISPR-Cas Systems: A Functional Perspective and Innovations. [PDF]

Int J Mol Sci
Navarro C, Díaz MP, Duran P, Castro A, Díaz A, Cano C, Carbonell-Zabaleta AK, Solano-Jimenez DS, Rivera-Porras D, Contreras-Velásquez JC, Bermúdez V.   +10 more
europepmc   +1 more source

Multiple cis‐regulatory elements collaborate to control mdka expression in telencephalic neural stem cells of adult zebrafish during constitutive and regenerative neurogenesis

The FEBS Journal, Volume 293, Issue 7, Page 1951-1969, April 2026.
midkine‐a (mdka), a pan‐injury response gene in vertebrates, is precisely regulated in the zebrafish telencephalon by a modular cis‐regulatory architecture. This control ensures proper expression during development, adult brain homeostasis, and regeneration.
Jincan Chen, Masanari Takamiya, Agnes Hendriks, Tanja Beil, Csilla Várnai, Nicolas Diotel, Sepand Rastegar   +6 more
wiley   +1 more source