Results 231 to 240 of about 28,349 (334)

Generalized Tonic Seizures Induced by a Unilateral Microinjection of Kainic Acid into the Pontine Reticular Formation in Rats [PDF]

open access: bronze, 1998
Takahiro Maeda   +4 more
openalex   +1 more source

Orexinergic neurons contribute to autonomic cardiovascular regulation for locomotor exercise

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study unveiled the essential role of the orexinergic nervous system in the central circuitry that transmits central command signals for locomotor exercise. We observed the excitation of orexinergic neurons by voluntary locomotor exercise in rats.
Emi Narai   +7 more
wiley   +1 more source

Acute introduction of monomeric or multimeric α‐synuclein induces distinct impacts on synaptic vesicle trafficking at lamprey giant synapses

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Monomeric and multimeric α‐synuclein were purified from HEK cells and delivered to lamprey reticulospinal (RS) synapses via axonal microinjection, followed by stimulation (20 Hz, 5 min). Ultrastructural analysis showed that both α‐synuclein species impaired intracellular vesicle trafficking, leading to synaptic vesicle loss and ...
Cristina Román‐Vendrell   +5 more
wiley   +1 more source

Uncovering the neural control of laryngeal activity and subglottic pressure in anaesthetized rats: insights from mesencephalic regions. [PDF]

open access: yesPflugers Arch
González-García M   +6 more
europepmc   +1 more source

Targeting necroptosis protects against astrocyte death and hippocampal sclerosis in experimental temporal lobe epilepsy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Experimentally induced status epilepticus induces microglial TNFα release, which binds to astrocytic TNFR1 and triggers activation of RIPK1/RIPK3/MLKL signalling, initiating necroptotic astrocytic death that contributes to the development of hippocampal sclerosis. Created with Biorender.com.
Zhou Wu   +3 more
wiley   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson   +7 more
wiley   +1 more source

Zebrafish in neurodevelopmental disorders studies: Genetic models and pathological involvement of microglia

open access: yesDevelopmental Medicine &Child Neurology, Volume 67, Issue 10, Page 1257-1265, October 2025.
The relevance of the pathogenic (de novo or inherited) mutations found in patients with neurodevelopmental disorders can be investigated using zebrafish as an animal model, by functional screening of the target genes and phenotypic assessments during both early development and adulthood. Abstract Neurodevelopmental disorders (NDDs) are a group of brain
Fatemeh Hassani Nia, Valerie Wittamer
wiley   +1 more source

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