Results 261 to 270 of about 28,349 (334)

Actin Filament Pointed Ends: Assays for Regulation of Assembly and Disassembly by Tropomodulin and Tropomyosin

Cytoskeleton, Volume 82, Issue 9, Page 571-591, September 2025.
ABSTRACT Actin filaments are dynamic polymers whose length depends on regulated monomer association and dissociation at their ends. Actin barbed‐end dynamics are relatively better understood, primarily due to the approximately tenfold faster subunit on/off rates at barbed versus pointed ends.
Sawako Yamashiro, Shashank Shekhar, Stefanie M. Novak, Sudipta Biswas, Carol C. Gregorio, Velia M. Fowler   +5 more
wiley   +1 more source

Highly Efficient Generation of Germline Mutations Using CRISPR/Cas9 in the Speckled Wood Butterfly <i>Pararge aegeria</i>. [PDF]

Ecol Evol
Shoshan AB, Tunström K, Wheat CW, Gotthard K.   +3 more
europepmc   +1 more source

Embryo development, pregnancy and twin delivery after microinjection of 'stump' spermatozoa

, 1999
R. J. Favero, Flavio Rizzo, B. Baccetti, Paola Piomboni   +3 more
openalex   +1 more source

Mitochondrial Diseases: Molecular Pathogenesis and Therapeutic Advances

MedComm, Volume 6, Issue 9, September 2025.
Key pathogenic mechanisms—OXPHOS defects, heteroplasmy, impaired mtDNA repair, disrupted dynamics/mitophagy, and inflammatory signaling—drive multiorgan involvement in mitochondrial diseases. Targeted interventions include metabolic drugs (CoQ10, idebenone, EPI‐743), mitochondrial gene editing (DdCBE, mitoBEs, CyDENT/mitoTALEN/mtZFN), and mitochondrial
Jialun Mei, Peng Ding, Chuan Gao, Jian Zhou, Zhiwei Li, Changqing Zhang, Junjie Gao   +6 more
wiley   +1 more source

Mitochondrial Dysfunction in Aging: Future Therapies and Precision Medicine Approaches

MedComm – Future Medicine, Volume 4, Issue 3, September 2025.
Mitochondria play a critical role in aging and aging‐related diseases. This review systematically explores the mechanisms underlying mitochondrial deterioration during aging and highlights innovative therapeutic strategies for these mitochondrial problems.
Lanlan Jia, Ziyu Wei, Jinyuan Luoqian, Xi Wang, Chao Huang   +4 more
wiley   +1 more source

Spinal collagen mesotherapy in patients with chronic thoracic back pain: a retrospective analysis of effectiveness and safety in a 3-month follow-up. [PDF]

Reumatologia
Koszela K, Woldańska-Okońska M, Skoczylas A, Słupiński M, Gasik R.   +4 more
europepmc   +1 more source

A Low Frequency of Chromosomal Integration of Cloned DNA after Microinjection into the Cytoplasm of Fertilized Eggs of Chickens.

, 1998
Katsutoshi Kino, Kenji Noda, Hiromitsu Miyakawa, Katsumasa OHTSUKA, Tamao Ono, Makoto Mochii, Goro Eguchi, Kiyokazu Agata   +7 more
openalex   +2 more sources

Zebrafish as a Versatile Model Organism: From Tanks to Treatment

MedComm – Future Medicine, Volume 4, Issue 3, September 2025.
The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava, Kalyani Eswar, Sasvat Sayee Ram Ramesh, Akshit Prajapati, Tanvi Sonpipare, Apoorva Basa, Mounika Gubige, Sribala Ponnapalli, Shashidhar Thatikonda, Aravind Kumar Rengan   +9 more
wiley   +1 more source

Neural circuitry of rapid eye movement sleep homeostasis: Mechanistic insights and pathological implications

Sleep Research, Volume 2, Issue 3, Page 128-144, September 2025.
Abstract Rapid eye movement (REM) sleep is a unique brain state crucial for emotion, memory, and plasticity. Unlike well‐understood non‐REM (NREM) sleep homeostasis, REM sleep homeostasis remains less clearly defined. This review highlights recent progress in understanding REM sleep homeostasis, focusing on its neurophysiological markers, neural ...
Ting He
wiley   +1 more source

Effects of microinjections of nicotine into the dorsal hippocampus on morphine- induced amnesia

Annals of General Psychiatry, 2008
Zarrindast Mohammad Reza, Rezayof Ameneh, Khajepour Lotfollah   +2 more
doaj   +1 more source