Results 101 to 110 of about 15,286 (297)

Dual‐Stage Microneedle Patch With Lipid Droplet‐Mediated ‘Capture‐Kill’ and Sustained Release for Enhanced Wound Healing

open access: yesAdvanced Science, EarlyView.
We report a lipid‐droplet‐engineered, gallium‐loaded sonodynamic therapeutic platform (LDTG) incorporated into a bilayer microneedle (MN) patch co‐delivering all‐trans retinoic acid (ATRA), termed LDTG A‐MNs, for synergistic antibacterial therapy and accelerated wound repair.
Peng Jiang   +9 more
wiley   +1 more source

Enhanced immunization via dissolving microneedle array-based delivery system incorporating subunit vaccine and saponin adjuvant

open access: yes, 2017
Ji-Hui Zhao,1,* Qi-Bo Zhang,1,* Bao Liu,2 Xiang-Hua Piao,1 Yu-Lu Yan,1 Xiao-Ge Hu,1 Kuan Zhou,1 Yong-Tai Zhang,1 Nian-Ping Feng1 1School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China ...
Zhao JH   +8 more
core  

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

open access: yesAdvanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

Novel stereo DIC characterisation of microneedle and hypodermic needle insertion

open access: yesFrontiers in Bioengineering and Biotechnology
IntroductionMicroneedles are minimally invasive devices, designed for pain-free drug delivery. Until now, the degree of strain exerted on the skin during microneedle insertion, in comparison to gold standard hypodermic needles, has not been quantified ...
Megan McNamee   +8 more
doaj   +1 more source

Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity

open access: yesAdvanced Science, EarlyView.
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang   +12 more
wiley   +1 more source

Biomineralized Nanocomposite‐Integrated Microneedle Patch for Combined Brachytherapy and Photothermal Therapy in Postoperative Melanoma Recurrence and Infectious Wound Healing

open access: yesAdvanced Science
In the surgical management of malignant melanoma, incomplete tumor resection and large‐area cutaneous defects are major contributors to high locoregional recurrence and uncontrolled wound infections, resulting in poor prognosis and prolonged recovery ...
Peng Liu   +7 more
doaj   +1 more source

Drug Diffusion Inside a Non-Degradable Hydrogel Microneedle [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering
Microneedles have shown great potential in drug delivery, but further research is needed to improve their performance. Studying drug release and distribution within microneedles using laboratory techniques can be challenging due to the small size of the ...
Hajar Moghadas, Navid Kashaninejad
doaj   +1 more source

Towards rapid 3D direct manufacture of biomechanical microstructures [PDF]

open access: yes
The field of stereolithography has developed rapidly over the last 20 years, and commercially available systems currently have sufficient resolution for use in microengineering applications.
King, Philip Huw
core  

Collection of Analytes from Microneedle Patches

open access: yes, 2015
Clinical medicine and public health would benefit from simplified acquisition of biological samples from patients that can be easily obtained at point of care, in the field, and by patients themselves.
Andrey V. Romanyuk (1341777)   +5 more
core   +1 more source

Stretchable Microelectrode Arrays with Microneedles for Reliable Electrophysiological Recording of Human Heart and Brain Organoids

open access: yesAdvanced Science, EarlyView.
A stretchable 3D microelectrode array with microneedles (3D MN‐sMEA) enables stable, minimally destructive electrophysiological monitoring of 3D organoids. The wafer‐level stud‐bump bonding process facilitates high‐fidelity recordings of heart and cerebral organoids.
Eunyoung Jang   +10 more
wiley   +1 more source

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