Results 91 to 100 of about 15,286 (297)

Computational and Experimental Analysis of Drug‐Coated Microneedle Skin Insertion: The Mode of Administration Matters

Advanced Materials Interfaces
Due to an incomplete understanding of the biomechanics of microneedle skin insertion for therapeutic delivery, translating microneedle device performance to clinical use remains challenging.
Wenting Shu, Thomas Lijnse, Fiona McCartney, David J. Brayden, Aisling Ní Annaidh, Eoin D. O'Cearbhaill   +5 more
doaj   +1 more source

Photographs of the fabricated microneedle patches.

, 2016
(a) Microneedle patch type A (higher Young’s modulus and lower flexibility). (b) Microneedle patch type B (lower Young’s modulus and higher flexibility).
Niclas Roxhed (3389630), Andreas Christin Fischer (3389639), Tommy Haraldson (3389642), Reza Zandi Shafagh (3389627), Wouter van der Wijngaart (3389636), Frank Niklaus (3333261), Mina Rajabi (3389624), Göran Stemme (3389633)   +7 more
core   +1 more source

Solid Ethanol as a Renewable, Low‐Toxicity, Electron‐Beam Direct Write, and Biomedical Material

Advanced Science, EarlyView.
3D ice lithography (3DIL) enables the fabrication of intricate submicrometer objects using ethanol as a renewable starting material. This study combines process optimization, structural and material analysis, and biomedical applications, from cell culture scaffolds to the patterning of neurostimulation electrodes, demonstrating performance in both in ...
Bruno Perdigão, Bingdong Chang, Gwendoline A. E. Anand, Lechan Tao, Kayeon Kim, Anne Zebitz Eriksen, Malte Alexander Schönhoff, Guilherme Ferreira, Xiyuan Liu, Su Genelioglu, Joachim Lyngholm‐Kjærby, Neha Zahoor, Johan Ulrik Lind, Alice Bastos da Silva Fanta, Thomas Willum Hansen, Changsi Cai, Anpan Han   +16 more
wiley   +1 more source

Interface Wettability Transition‐Driven Drug Release and Dual‐Phase Functionalization in Implant Abutment

Advanced Science, EarlyView.
A temporally controlled drug release coating is developed for abutments using a superhydrophobic coating self‐assembled on mesoporous silica. This surface provides sequential functionality: initial contamination resistance through non‐wetting, followed by controlled drug release via wettability transition.
Zhongchao Wang, Liang Shi, MingXia Li, Xiao Han, Jinghan Wang, Guangping Wang, Dan Zou, Bingyang Lu, Liyuan Fan   +8 more
wiley   +1 more source

Breathable core–shell microneedle patches for diabetic wound treatment

Materials Futures
Microneedles have demonstrated valuable applications in diabetic wound management. Many endeavors are devoted to developing microneedles with well-designed structures and enhanced functions.
Lu Fan, Yu Wang, Li Wang, Xiang Lin, Xiaoju Wang, Luoran Shang, Hongbo Zhang, Yuanjin Zhao   +7 more
doaj   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Microneedle technologies

Drug Delivery and Translational Research, 2021
Choi, Seong-O, Park, Jung-Hwan
openaire   +3 more sources

A Portable and Dual‐Button Microneedle Device Enables Intelligent Multimodal Laser Sensing

Advanced Science, EarlyView.
A portable and dual‐button microneedle device enables rapid interstitial fluid sampling. Coupled with multimodal laser sensing and AI‐assisted data processing, the platform enables simultaneous molecular and elemental analysis for minimally invasive and multiplexed health assessment toward point‐of‐care diagnostics.
Yuanchao Liu, Xiujuan Hu, Shengqun Shi, Bowen Li, Zhixing Ge, Yunchen Long, Chaochao Sun, Annan Chen, Bingbing Gao, Lianbo Guo, Condon Lau, Wei Luo, Chwee Teck Lim   +12 more
wiley   +1 more source

Gouty Arthritic Microenvironment Triggered Core–Shell Microneedles for Hydrogen‐Enzyme Synergistic Gout Therapy

Small Structures
Gouty arthritis (GA) is a chronic and progressive disease generally characterized by high articular uric acid (UA) levels and an inflammatory immune microenvironment.
Jiajun Miao, Jiamiao Jiang, Wenxin Xu, Haiying Liang, Lu Liu, Haixin Tan, Xiaoting Zhang, Yicheng Ye, Hanfeng Qin, Junbin Gao, Hao Tian, Fei Peng, Yunrui Hu, Shaoheng Zhang, Yingfeng Tu, Shuai Han   +15 more
doaj   +1 more source

Microneedle Patterning of 3D Nonplanar Surfaces on Implantable Medical Devices Using Soft Lithography

Micromachines, 2019
Micropatterning is often used to engineer the surface properties of objects because it allows the enhancement or modification of specific functionalities without modification of the bulk material properties.
Sun-Joo Jang, Tejas Doshi, Jerusalem Nerayo, Alexandre Caprio, Seyedhamidreza Alaie, Jordyn Auge, James K. Min, Bobak Mosadegh, Simon Dunham   +8 more
doaj   +1 more source