Results 81 to 90 of about 15,286 (297)

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

open access: yesAdvanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka   +4 more
wiley   +1 more source

Formulation and Evaluation of PLGA Nanoparticulate-Based Microneedle System for Potential Treatment of Neurological Diseases

open access: yes, 2023
Baohua Li,1,2,* Geng Lu,1,2 Wenbin Liu,3,* Liqi Liao,2 Junfeng Ban,1,2 Zhufen Lu1 1Guangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangdong Provincial Engineering Center of Topical Precise Drug Delivery System, Guangdong ...
Liao L, Lu G, Ban J, Lu Z, Li B, Liu W
core  

Microneedles for Drug Delivery [PDF]

open access: yesPharmaceutical Research, 2010
The theme section highlighted in this issue of Pharmaceutical Research provides a snapshot of the latest information on today’s microneedle research and development, predominately in transdermal applications. Fifteen original papers from academia and industry cover research and development of microneedles from concept to human clinical studies and ...
openaire   +2 more sources

Microneedling: a review

open access: yesRevista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Sugery, 2020
Introduction: Microneedling, also called percutaneous collagen induction therapy (PCIT), is a technique applied with an equipment called roller. It is suitable for rejuvenation, alopecia, all types of scars, acne, photo rejuvenation, stretch marks, skin flaccidity, melasma, expression wrinkles, and improvement of the general aspect of the skin ...
Adriana Da Silva Ferreira   +2 more
openaire   +2 more sources

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

open access: yesAdvanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang   +10 more
wiley   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

open access: yesAdvanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Stabilization of influenza vaccine enhances protection by microneedle delivery in the mouse skin.

open access: yesPLoS ONE, 2009
BackgroundSimple and effective vaccine administration is particularly important for annually recommended influenza vaccination. We hypothesized that vaccine delivery to the skin using a patch containing vaccine-coated microneedles could be an attractive ...
Fu-Shi Quan   +5 more
doaj   +1 more source

Microneedle-Assisted Topical Delivery of Photodynamically Active Mesoporous Formulation for Combination Therapy of Deep-Seated Melanoma

open access: yes, 2018
Topical treatment using photodynamic therapy (PDT) for many types of skin cancers has largely been limited by the inability of existing photosensitizers to penetrate into the deep skin tissue.
Wei Qi Lim (4375810)   +26 more
core   +1 more source

Shark Tooth-Inspired Microneedle Dressing for Intelligent Wound Management

open access: yes, 2021
Intelligent management beyond therapeutic drug treating holds significant prospects in facilitating the recovery of intractable chronic wounds.
Bingbing Gao (1700473)   +3 more
core   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

open access: yesAdvanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi   +13 more
wiley   +1 more source

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