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Advances of Microneedles in Biomedical Applications [PDF]

open access: yesMolecules, 2021
A microneedle (MN) is a painless and minimally invasive drug delivery device initially developed in 1976. As microneedle technology evolves, microneedles with different shapes (cone and pyramid) and forms (solid, drug-coated, hollow, dissolvable and ...
Jie Xu   +3 more
doaj   +4 more sources

Polymeric Microneedles: An Emerging Paradigm for Advanced Biomedical Applications

open access: yesScientia Pharmaceutica, 2023
Microneedles are gaining popularity as a new paradigm in the area of transdermal drug delivery for biomedical and healthcare applications. Efficient drug delivery with minimal invasion is the prime advantage of microneedles.
Deepak Kulkarni   +10 more
doaj   +2 more sources

Silk Fibroin Microneedles for Transdermal Drug Delivery: Where Do We Stand and How Far Can We Proceed?

open access: yesPharmaceutics, 2023
Microneedles are a patient-friendly technique for delivering drugs to the site of action in place of traditional oral and injectable administration.
Zhenzhen Qi   +7 more
doaj   +2 more sources

Versatile Ice Microneedles for Transdermal Delivery of Diverse Actives

open access: yesAdvanced Science, 2021
Microneedles are regarded as an emerging and promising transdermal drug delivery strategy. Great efforts are devoted to getting rid of their material restrictions and imparting them with abilities to carry various drugs.
Xiaoxuan Zhang   +2 more
exaly   +2 more sources

Hard polymeric porous microneedles on stretchable substrate for transdermal drug delivery

open access: yesScientific Reports, 2022
Microneedles offer a convenient transdermal delivery route with potential for long term sustained release of drugs. However current microneedle technologies may not have the mechanical properties for reliable and stable penetration (e.g.
Aydin Sadeqi   +4 more
doaj   +2 more sources

Microneedles: A New Generation Vaccine Delivery System

open access: yesMicromachines, 2021
Transdermal vaccination route using biodegradable microneedles is a rapidly progressing field of research and applications. The fear of painful needles is one of the primary reasons most people avoid getting vaccinated.
Ipshita Menon   +7 more
doaj   +2 more sources

A Fully Integrated Closed‐Loop System Based on Mesoporous Microneedles‐Iontophoresis for Diabetes Treatment

open access: yesAdvanced Science, 2021
A closed‐loop system that can mini‐invasively track blood glucose and intelligently treat diabetes is in great demand for modern medicine, yet it remains challenging to realize.
Fanmao Liu   +2 more
exaly   +2 more sources

A Review of 3D-Printing of Microneedles

open access: yesPharmaceutics, 2022
Microneedles are micron-sized devices that are used for the transdermal administration of a wide range of active pharmaceutics substances with minimally invasive pain. In the past decade, various additive manufacturing technologies have been used for the
Michael Olowe   +2 more
doaj   +2 more sources

Sugar-Triggered Burst Drug Releasing Poly-Lactic Acid (PLA) Microneedles and Its Fabrication Based on Solvent-Casting Approach

open access: yesPharmaceutics, 2022
Microneedles have emerged as a novel transdermal delivery tool that enables the delivery of various products such as drugs, vaccines, or cosmetic ingredients. Although the demand for solid microneedles composed of biocompatible polymer is increasing, the
Seongsu Kang   +4 more
doaj   +2 more sources

Functionalized Polymeric Microneedles for Transdermal Delivery of Ovalbumin Protein Antigen [PDF]

open access: yesPharmaceutics
Background/Objectives: Microneedles represent an innovative transdermal drug delivery approach, especially for protein antigens. This study aimed to develop a dual-functional, dissolvable microneedle system loaded with β-glucan and fucoidan in a ...
Yi Liu   +8 more
doaj   +2 more sources

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