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Advances of Microneedles in Biomedical Applications [PDF]
A microneedle (MN) is a painless and minimally invasive drug delivery device initially developed in 1976. As microneedle technology evolves, microneedles with different shapes (cone and pyramid) and forms (solid, drug-coated, hollow, dissolvable and ...
Jie Xu+3 more
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Polymeric Microneedles: An Emerging Paradigm for Advanced Biomedical Applications
Microneedles are gaining popularity as a new paradigm in the area of transdermal drug delivery for biomedical and healthcare applications. Efficient drug delivery with minimal invasion is the prime advantage of microneedles.
Deepak Kulkarni+10 more
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Microneedles are a patient-friendly technique for delivering drugs to the site of action in place of traditional oral and injectable administration.
Zhenzhen Qi+7 more
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Versatile Ice Microneedles for Transdermal Delivery of Diverse Actives
Microneedles are regarded as an emerging and promising transdermal drug delivery strategy. Great efforts are devoted to getting rid of their material restrictions and imparting them with abilities to carry various drugs.
Xiaoxuan Zhang+2 more
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Hard polymeric porous microneedles on stretchable substrate for transdermal drug delivery
Microneedles offer a convenient transdermal delivery route with potential for long term sustained release of drugs. However current microneedle technologies may not have the mechanical properties for reliable and stable penetration (e.g.
Aydin Sadeqi+4 more
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Microneedles: A New Generation Vaccine Delivery System
Transdermal vaccination route using biodegradable microneedles is a rapidly progressing field of research and applications. The fear of painful needles is one of the primary reasons most people avoid getting vaccinated.
Ipshita Menon+7 more
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A closed‐loop system that can mini‐invasively track blood glucose and intelligently treat diabetes is in great demand for modern medicine, yet it remains challenging to realize.
Fanmao Liu+2 more
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A Review of 3D-Printing of Microneedles
Microneedles are micron-sized devices that are used for the transdermal administration of a wide range of active pharmaceutics substances with minimally invasive pain. In the past decade, various additive manufacturing technologies have been used for the
Michael Olowe+2 more
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Microneedles have emerged as a novel transdermal delivery tool that enables the delivery of various products such as drugs, vaccines, or cosmetic ingredients. Although the demand for solid microneedles composed of biocompatible polymer is increasing, the
Seongsu Kang+4 more
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Functionalized Polymeric Microneedles for Transdermal Delivery of Ovalbumin Protein Antigen [PDF]
Background/Objectives: Microneedles represent an innovative transdermal drug delivery approach, especially for protein antigens. This study aimed to develop a dual-functional, dissolvable microneedle system loaded with β-glucan and fucoidan in a ...
Yi Liu+8 more
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