Results 11 to 20 of about 33,747 (400)
Microneedles in Action: Microneedling and Microneedles-Assisted Transdermal Delivery
Polymers, 2022 Human skin is a multilayered physiochemical barrier protecting the human body. The stratum corneum (SC) is the outermost keratinized layer of skin through which only molecules with less or equal to 500 Da (Dalton) in size can freely move through the skin.
D. Lim, Hong-jun Kim
semanticscholar +3 more sources
Smart Microneedles for Therapy and Diagnosis [PDF]
Research, 2020 Microneedles represent a cutting-edge and idea-inspiring technology in biomedical engineering, which have attracted increasing attention of scientific researchers and medical staffs. Over the past decades, numerous great achievements have been made.
Xiaoxuan Zhang +3 more
doaj +4 more sources
Microneedle Optimization: Toward Enhancing Microneedle's Functionality and Breaking the Traditions
Small StructuresMicroneedles hold remarkable potential for providing convenient and unique solutions for disease diagnosis and therapy. However, their integration into clinical practices has been slow, primarily due to the challenge of developing models that meet the ...
Elham Lori Zoudani +2 more
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Scarless wound healing programmed by core-shell microneedles
Nature Communications, 2023 Effective reprogramming of chronic wound healing remains challenging due to the limited drug delivery efficacy hindered by physiological barriers, as well as the inappropriate dosing timing in distinct healing stages.
Ying Zhang +13 more
semanticscholar +1 more source
Microneedles: materials, fabrication, and biomedical applications
Biomedical microdevices, 2023 The microneedles have attracted great interests for a wide range of transdermal biomedical applications, such as biosensing and drug delivery, due to the advantages of being painless, semi-invasive, and sustainable.
Xiaojin Luo, Li Yang, Yue Cui
semanticscholar +1 more source
Advanced Materials Interfaces, 2023 Although interstitial fluid (ISF) is recognized as an important source of biomarkers, it is difficult and time‐consuming to extract, thus limiting its use in medical diagnostic and clinical settings.
K. Saifullah, Zahra Faraji Rad
semanticscholar +1 more source
Microneedle, bio-microneedle and bio-inspired microneedle: A review [PDF]
Journal of Controlled Release, 2017 Microneedles (MNs) are micro-scale needles used for drug delivery and other targets. Micro-scale size endows them with many advantages over hypodermic needles, including painlessness, minimal invasiveness and convenient operation, but it may also lead to risk of mechanical failures, which should be prevented in the clinical applications of MNs.
Chengwei Wu, G. J. Ma
openaire +2 more sources
Research progress in hydrogel microneedle
Cailiao gongcheng, 2023 Microneedles (MN) as a minimally invasive device consisting of a micro-raised array, can penetrate the cuticle to the epidermis and dermis, and which has the advantages of safety, painless, minimally invasive, self-administration and convenience.
LIU Guodong +5 more
doaj +1 more source
Pharmaceutics, 2023 Hyaluronidase is clinically used in treating many skin diseases due to its good permeability-promoting effect, which may motivate the diffusion and absorption of drugs. To verify the penetration osmotic effect of hyaluronidase in microneedles, 55 nm-size
Xiaoqing Miao +3 more
doaj +1 more source
Small, 2023 Conductive polymeric microneedle (MN) arrays as biointerface materials show promise for the minimally invasive monitoring of analytes in biodevices and wearables. There is increasing interest in microneedles as electrodes for biosensing, but efforts have
Antonios Keirouz +6 more
semanticscholar +1 more source