Results 31 to 40 of about 37,259 (377)

Smart Microneedles for Therapy and Diagnosis

open access: yesResearch, 2020
Microneedles represent a cutting-edge and idea-inspiring technology in biomedical engineering, which have attracted increasing attention of scientific researchers and medical staffs. Over the past decades, numerous great achievements have been made.
Xiaoxuan Zhang   +3 more
doaj   +1 more source

Electrochemical Microneedles: Innovative Instruments in Health Care

open access: yesBiosensors, 2022
As a significant part of drug therapy, the mode of drug transport has attracted worldwide attention. Efficient drug delivery methods not only markedly improve the drug absorption rate, but also reduce the risk of infection.
Zhijun Liao, Qian Zhou, Bingbing Gao
doaj   +1 more source

Three-Dimensional (3D) Printed Microneedles for Microencapsulated Cell Extrusion [PDF]

open access: yes, 2018
Cell-hydrogel based therapies offer great promise for wound healing. The specific aim of this study was to assess the viability of human hepatocellular carcinoma (HepG2) cells immobilized in atomized alginate capsules (3.5% (w/v) alginate, d = 225 µm ...
Bouzos, Evangelia   +6 more
core   +3 more sources

Microneedles for Efficient and Precise Drug Delivery in Cancer Therapy

open access: yesPharmaceutics, 2023
Cancer is the leading cause of death, acting as a global burden, severely impacting the patients’ quality of life and affecting the world economy despite the expansion of cumulative advances in oncology.
K. Ganeson   +5 more
semanticscholar   +1 more source

Skin Cell Proliferation Stimulated by Microneedles [PDF]

open access: yes, 2012
A classical wound may be defined as a disruption of tissue integrity. Wounds, caused by trauma from accidents or surgery, that close via secondary intention rely on the biological phases of healing, i.e., hemostasis, inflammation, proliferation, and ...
Kloth, Luther C., Liebl, Horst
core   +2 more sources

Evaluation of Microparticulate Ovarian Cancer Vaccine via Transdermal Route of Delivery [PDF]

open access: yes, 2016
Ovarian cancer is the fifth most commonly occurring malignancy in women, with the highest mortality rate among all the gynecological tumors. Microparticulate vaccine can serve as an immunotherapeutic approach with a promising antigenic delivery system ...
Akalkotkar, Archana   +3 more
core   +2 more sources

The Role of 3D Printing Technology in Microengineering of Microneedles.

open access: yesSmall, 2022
Microneedles (MNs) are minimally invasive devices, which have gained extensive interest over the past decades in various fields including drug delivery, disease diagnosis, monitoring, and cosmetics.
Usanee Detamornrat   +4 more
semanticscholar   +1 more source

Transdermal Delivery of Drugs with Microneedles—Potential and Challenges

open access: yesPharmaceutics, 2015
Transdermal drug delivery offers a number of advantages including improved patient compliance, sustained release, avoidance of gastric irritation, as well as elimination of pre-systemic first-pass effect.
Kevin Ita
doaj   +1 more source

A dose-ranging study in older adults to compare the safety and immunogenicity profiles of MF59®-adjuvanted and non-adjuvanted seasonal influenza vaccines following intradermal and intramuscular administration [PDF]

open access: yes, 2014
Strategies to optimize responses to seasonal influenza vaccination in older adults include the use of adjuvants, higher antigen doses, and intradermal delivery.
Castellino, Flora   +9 more
core   +1 more source

Biodegradable double-network GelMA-ACNM hydrogel microneedles for transdermal drug delivery

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
As a minimally invasive drug delivery platform, microneedles (MNs) overcome many drawbacks of the conventional transdermal drug delivery systems, therefore are favorable in biomedical applications. Microneedles with a combined burst and sustained release
Wensheng Lin   +15 more
doaj   +1 more source

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