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This research paper was performed to study and utilizes two kinds of materials which match with two different fabrications in order to design an ideal shape of microneedles. The technology employs the polymer microneedles and the silicon microneedles with the height of 236 mum and 350 mum respectively.
Chin-Chun Hsu+3 more
openaire +4 more sources
Microneedle permits transdermal biosensing and drug delivery with minor pain. However, accurate microneedle transdermal positioning with minimal skin deformation remains a significant technical challenge due to inhomogeneous skin topology and ...
Yilin Cai+6 more
doaj +1 more source
Breast Cancer Vaccine: Are We There Yet? [PDF]
In lieu of an abstract, here is the article\u27s first paragraph: Breast cancer is the most fatal form of cancer for female population worldwide. National Cancer Institute (NCI) estimates 226,870 females and 2,190 males to be diagnosed with breast cancer
Chablani, Lipika
core +2 more sources
Microneedle technologies have been developed for dermal drug and vaccine delivery, including hollow-, solid-, coated-, and dissolving microneedles. Microneedles have been made in many different geometries and of many different materials, all of which may
Mara Leone+8 more
doaj +1 more source
Responsive Microneedles as a New Platform for Precision Immunotherapy
Microneedles are a well-known transdermal or transdermal drug delivery system. Different from intramuscular injection, intravenous injection, etc., the microneedle delivery system provides unique characteristics for immunotherapy administration ...
Xinyang Liu+3 more
doaj +1 more source
This review summarizes recent developments in microneedle-based bioassays.
Wujin Sun+4 more
openaire +4 more sources
Inhibition and relaxation of sea urchin sperm flagella by vanadate [PDF]
Direct measurements of the stiffness (elastic bending resistance) of demembranated sera urchin sperm flagella were made in the presence of MgATP2- and vanadate.
Okuno, Makoto
core +3 more sources
Revolutionizing diabetic wound healing: The power of microneedles
Diabetic wounds significantly affect patient quality of life. Microneedles are a promising treatment to accelerate wound healing owing to their high drug-loading capacity and efficient drug delivery; however, few studies to date have comprehensively ...
Chun Liang+9 more
doaj
Microneedle radiofrequency (RF) is a breakthrough in targeting skin laxity and rhytids that provides direct in situ delivery, impedance measurements, temperature measurements, energy delivery controls, and targeting of various skin depths to achieve desired clinical outcomes.
openaire +3 more sources
Microneedle-Based Vaccines [PDF]
The threat of pandemic influenza and other public health needs motivate the development of better vaccine delivery systems. To address this need, microneedles have been developed as micron-scale needles fabricated using low-cost manufacturing methods that administer vaccine into the skin using a simple device that may be suitable for self ...
John A. Mikszta+3 more
openaire +3 more sources