Results 61 to 70 of about 37,259 (377)
Inhibition and relaxation of sea urchin sperm flagella by vanadate [PDF]
, 1980 Direct measurements of the stiffness (elastic bending resistance) of demembranated sera urchin sperm flagella were made in the presence of MgATP2- and vanadate.
Okuno, Makoto
core +3 more sources
Microneedle-Based Vaccines [PDF]
, 2009 The threat of pandemic influenza and other public health needs motivate the development of better vaccine delivery systems. To address this need, microneedles have been developed as micron-scale needles fabricated using low-cost manufacturing methods that administer vaccine into the skin using a simple device that may be suitable for self ...
Mark R, Prausnitz +3 more
openaire +2 more sources
Separable arrowhead microneedles [PDF]
Journal of Controlled Release, 2011 Hypodermic needles cause pain and bleeding, produce biohazardous sharp waste and require trained personnel. To address these issues, we introduce separable arrowhead microneedles that rapidly and painlessly deliver drugs and vaccines to the skin. These needles are featured by micron-size sharp tips mounted on blunt shafts.
Leonard Y, Chu, Mark R, Prausnitz
openaire +2 more sources
Substrate Deformation Predicts Neuronal Growth Cone Advance [PDF]
, 1977 Although pulling forces have been observed in axonal growth for several decades, their underlying mechanisms, absolute magnitudes, and exact roles are not well understood.
Athamneh, Ahmad I.M. +3 more
core +1 more source
Materials, 2023 Transdermal drug delivery is a new means of delivering drugs through the skin to achieve therapeutic effects. Microneedles have several advantages, including low cost, easy self-administration, and high delivery efficiency.
Na Qiang +7 more
semanticscholar +1 more source
Polymer multilayer tattooing for enhanced DNA vaccination [PDF]
, 2012 DNA vaccines have many potential benefits but have failed to generate robust immune responses in humans. Recently, methods such as in vivo electroporation have demonstrated improved performance, but an optimal strategy for safe, reproducible, and pain ...
Barouch, Dan H. +7 more
core +1 more source
The Progress in the Application of Dissolving Microneedles in Biomedicine
Polymers, 2023 In recent years, microneedle technology has been widely used for the transdermal delivery of substances, showing improvements in drug delivery effects with the advantages of minimally invasive, painless, and convenient operation.
Xueqing Yu, Jing Zhao, Daidi Fan
semanticscholar +1 more source
Frontiers in Bioengineering and Biotechnology, 2018 In this study we present the fabrication of multilayer microneedles with circular obelisk and beveled-circular obelisk geometries, which have potential applications in implantable drug delivery devices.
Min Jung Kim +7 more
doaj +1 more source
Poly(lactic-co-glycolic) acid drug delivery systems through transdermal pathway : an overview [PDF]
, 2017 In past few decades, scientists have made tremendous advancement in the field of drug delivery systems (DDS), through transdermal pathway, as the skin represents a ready and large surface area for delivering drugs.
AE Porter +37 more
core +2 more sources
Research, 2022 Microneedle permits transdermal biosensing and drug delivery with minor pain. However, accurate microneedle transdermal positioning with minimal skin deformation remains a significant technical challenge due to inhomogeneous skin topology and ...
Yilin Cai +6 more
doaj +1 more source