Results 141 to 150 of about 24,177 (264)

Morphological diversity of the micronuclei in Paramecium

, 1997
Morphological analysis of the micronuclei in 51 stocks of 10 Paramecium species was carried out to examine the diversity of the nuclear morphology in these organisms.
FOKIN, SERGEY
core  

Advances in Cancer Immunotherapy for Solid Tumors

Advanced Science, Volume 13, Issue 35, 24 June 2026.
Cancer immunotherapy for solid tumors is rapidly evolving beyond classical checkpoint blockade toward more precise strategies. Emerging checkpoint targets, bispecific antibodies, antibody–drug conjugate combinations, personalized vaccines, cellular therapies, and engineered cytokines are expanding therapeutic possibilities, while biomarker‐guided ...
Shira Gabizon‐Peretz, Harriet M. Kluger   +1 more
wiley   +1 more source

In Vitro and In Vivo Genotoxicity of Polystyrene Microplastics: Evaluation of a Possible Synergistic Action with Bisphenol A

Journal of Xenobiotics
The ubiquitous presence of plastics represents a global threat for all ecosystems and human health. In this study, we evaluated, in vitro and in vivo, the genotoxic potential of different concentrations of polystyrene microplastics (PS-MPs) and their ...
Alfredo Santovito, Mattia Lambertini, Alessandro Nota   +2 more
doaj   +1 more source

Micronuclei containing whole chromosomes harbouring the selectable gene do not lead to mutagenesis.

, 1997
Loss of heterozygosity is one genetic change observed in many tumours. We do not know whether the loss of chromosomal material through micronucleus formation is a viable mechanism associated with, and possibly leading to, genetic disease.
Caspary, W.J., Nüsse, M., Liechty, M.C., Eckert, I., Davis, L.M., Stopper, H.   +5 more
core   +1 more source

Environmental Transformation and Trophic Transfer of Engineered Nanomaterials in the Agri‐Food Chain and Implications for human Health

ChemFoodChem, Volume 2, Issue 2, June 2026.
ABSTRACT Engineered nanomaterials (ENMs) are increasingly applied in agriculture to improve crop yield, nutrient efficiency, and food quality. This study examines the environmental transformation of ENMs, their uptake in plants, and their transfer across the agri‐food chain leading to human exposure.
Soumitra Nath
wiley   +1 more source

Age-Dependent Inclusion of Sex Chromosomes in Lymphocyte Micronuclei of Man

, 1998
SummaryTwo-color centromeric FISH was used to study the inclusion of the X and Y chromosomes in micronuclei of cultured lymphocytes from 10 men representing two age groups (21–29 years and 51–55 years).
H. Norppa, J. Catalán, K. Autio, E. Kuosma, Autio, K., Kuosma, E., Norppa, H., Catalán, J.   +7 more
core   +1 more source

In Vitro Live Cell Imaging Reveals Nuclear Dynamics and Role of the Cytoskeleton During Asymmetric Division of Pollen Mitosis I in Nicotiana Benthamiana

Cytoskeleton, Volume 83, Issue 6, Page 394-406, June 2026.
ABSTRACT Pollen is a male gametophyte of angiosperms. Following meiosis, the microspore undergoes an asymmetric division called pollen mitosis I (PMI), which produces two cells of different sizes: a large vegetative cell and a small generative cell. Polarized nuclear migration and positioning during PMI are important for successful pollen development ...
Yoko Mizuta, Masako Igarashi, Tomomi Shinagawa, Ikuma Kaneshiro, Haoto Anan, Daisuke Kurihara   +5 more
wiley   +1 more source

Evaluation of the mutagenic effect of the iodinated contrast medium Urografina^® 292 using the micronucleus test in mouse bone marrow cells

Anais da Academia Brasileira de Ciências, 2013
Contrast media (CM) are frequently used in diagnostic radiology and in radiotherapy as a diagnostic tool and in treatment planning. Previous studies have demonstrated that these compounds induce chromosomal aberrations. This study evaluates the mutagenic
MÔNICA B.B. BELLE, DANIELA D. LEFFA, DALIANE MAZZORANA, VANESSA M. DE ANDRADE   +3 more
doaj  

DNA synthesis in radiation-induced micronuclei studied by bromodeoxyuridine (BrdUrd) labelling and anti-BrdUrd antibodies.

, 1990
DNA synthesis in radiation-induced micronuclei of Chinese hamster cells was studied as a function of time after irradiation using pulse labelling of cells with bromodeoxyuridine (BrdUrd) and an immunofluorescence technique with anti-BrdUrd antibodies. It
Kramer, J., Nüsse, M., Schaich-Walch, G.   +2 more
core  

Benzo[b]fluoranthene Induces Mutation Accumulation and Cancer‐Relevant Mutational Signatures in Mouse Lung Alongside Steady State Levels of Chromosome Damage in Blood

Environmental and Molecular Mutagenesis, Volume 67, Issue 5-7, June‐August 2026.
ABSTRACT Polycyclic aromatic hydrocarbons (PAHs) are well‐known for their mutagenic and carcinogenic effects. Benzo[b]fluoranthene (BbF) is one of 16 PAHs prioritized by the US Environmental Protection Agency for toxicological evaluation due to pervasive human exposure.
Xinwen Zhang, Cheryl A. Hobbs, Miriam V. Rivas, Alex Diesing, Danielle P. M. LeBlanc, Gu Zhou, Julie F. Foley, Paul A. White, Francesco Marchetti, Carole L. Yauk, Stephanie L. Smith‐Roe   +10 more
wiley   +1 more source