Results 121 to 130 of about 26,946 (241)
Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina
Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella +2 more
wiley +1 more source
Journal of Applied Toxicology, Volume 46, Issue 10, Page 3446-3454, October 2026.ABSTRACT Tartrazine is a synthetic azo dye widely used in food, pharmaceutical, and cosmetic products, resulting in extensive human exposure, while its toxicity and that of its primary metabolite, sulfanilic acid, remain controversial. Considering the reported association of tartrazine with hypersensitivity and allergic‐like reactions, human bronchial ...
Merve Baysal +5 more
wiley +1 more source
, 1995 The proportion of exfoliated buccal mucosal cells with micronuclei gives the opportunity to assess sensitivity to gamma-radiation and genotoxic compounds and in addition to monitor the effectiveness of cancer intervention strategies.
Copper, M P +4 more
core
MedComm, Volume 7, Issue 10, October 2026.Polyploid giant cancer cells (PGCCs) arise in response to stress and play a critical role in therapy resistance and tumor dormancy. These cells can evade conventional treatments and later contribute to cancer relapse by generating progeny through nonmitotic, amitotic mechanisms.
Silvia Guil‐Luna +3 more
wiley +1 more source
Posttranslational Modifications of p62/SQSTM1 in Health and Disease
MedComm, Volume 7, Issue 10, October 2026.Schematic illustration of p62 as a posttranslational modifications (PTMs)‐programmed integrator in homeostasis, pathogenesis, and therapeutic targeting. (Left) Homeostasis: In physiological states, p62, through various PTMs such as phosphorylation, ubiquitination, and acetylation, coordinates essential cellular functions.
Weikai Wang +8 more
wiley +1 more source
Micronuclei analysis in the hepatocytes of alcohol-fed rats.
, 2013 A, B) Dividing cells showing normal nuclei and micronuclei in hepatocytes of alcohol-fed rats. BN: Binucleated; MN: Mononucleus; MNi: Micronucleus; C) Effect of catechin on the extent of micronuclei formation in hepatocytes of alcohol- administered rats.
Sushma Bharrhan (350347) +3 more
core +1 more source
Preclinical and Toxicology Studies of LPM7100328, a Novel Oral GnRH Antagonist
Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.ABSTRACT LPM7100328 is a novel oral GnRH antagonist being developed for the prevention of premature luteinizing hormone (LH) surges in women undergoing controlled ovarian stimulation. The studies presented herein reported assessment of safety in favor of human clinical trials.
Yao Wang +9 more
wiley +1 more source
FISH Analysis on Spontaneously Arising Micronuclei in the ICF Syndrome [PDF]
, 1995 The ICF syndrome is a rare disorder where patients show undercondensation of the heterochromatic blocks of chromosomes 1, 9, and 16 along with variable immunodeficiency.
Stacey, Michael W. +2 more
core
Untreated Hair Dye Effluents Enter the Environment: Are They a Threat to Human Health?
Environmental Toxicology, Volume 41, Issue 10, Page 998-1010, October 2026.ABSTRACT The effluents generated during the process of hair dyeing exhibit a complex composition, comprising chemical compounds with varying toxicity levels. While the adverse impact of hair dyes on human health is acknowledged, there is a notable absence of studies addressing the toxicity associated with effluents produced during these activities. The
Letícia Cristina Gonçalves +3 more
wiley +1 more source
Micronuclei Formation in CHO-K1 Cells.
, 2012 a% micronuclei in binucleated cells.bstatistically significant by ANOVA followed by Dunn’s post hoc test ...
Liz Kuriakose (144764) +7 more
core +1 more source