Results 121 to 130 of about 24,177 (264)
Green and conventional synthesis routes produce ZnO nanoparticles with tunable physicochemical properties for food applications, ZnO‐NPs enhance antimicrobial activity, UV protection, and food preservation through ROS generation and ZN2+ release. However, particle dissolution, migration, cytotoxicity, and environmental concerns highlight the need for ...
Liza Akter +6 more
wiley +1 more source
Micronuclei Formation in A549 Cells.
a% micronuclei in binucleated cells.bstatistically significant by ANOVA followed by Dunn’s post hoc test ...
Liz Kuriakose (144764) +7 more
core +1 more source
In HepG2 cells, Aroclor 1254 induced oxidative stress, DNA damage, apoptosis, and mutagenicity; co‐treatment with curcumin restored antioxidant defenses (GSH/thiols; SOD, CAT, GPx, GR, TrxR), reduced ROS and comet/8‐OHdG readouts, and attenuated caspase activation, demonstrating curcumin's hepatoprotective and genoprotective modulation of PCB toxicity.
Pınar Erkekoğlu +3 more
wiley +1 more source
ANALYSIS OF SPERMATIDS MICRONUCLEI UNDER THE INFLUENCE OF ACRYLAMIDE
The micronucleus test is an effective method for determination of the evolution of genotoxic or clastogenic agents of physical and chemical functions.
K. THYAGARAJU +6 more
core +2 more sources
The pivotal role of β‐lactone stereochemistry in the development of SARS‐CoV‐2 Mpro inhibitors
Abstract From the arrival of the SARS‐CoV‐2 coronavirus in 2019 and its associated COVID‐19 pandemic, worldwide efforts have been focused on developing a drug to treat patients. The SARS‐CoV‐2 main protease (Mpro) is one of the main targets for drug design due to its key role in the virus replication and its distinguished ability to cleave peptides ...
Katarzyna Świderek, Vicent Moliner
wiley +1 more source
Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez +6 more
wiley +1 more source
The proportion of exfoliated buccal mucosal cells with micronuclei gives the opportunity to assess sensitivity to gamma-radiation and genotoxic compounds and in addition to monitor the effectiveness of cancer intervention strategies.
Copper, M P +4 more
core
HTC binucleated cells with micronuclei (arrow) (A and B).
HTC binucleated cells with micronuclei (arrow) (A and B).
Luciano Lucchetta (632609) +3 more
core +1 more source
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto +14 more
wiley +1 more source
Micronuclei to detect in vivo chemotherapy damage in a p53 mutated solid tumour.
Apoptosis induction and micronuclei formation were compared following cytotoxic treatments in two rat glioma differing in p53 integrity. In vitro, micronuclei emergence but not apoptosis was linked to the p53 mutated status.
Giannakopoulos, Xenofon +15 more
core +1 more source

