Results 101 to 110 of about 26,946 (241)

Chemoprotective effect of cysteamine against the induction of micronuclei by methyl methanesulfonate and cyclophosphamide

Genetics and Molecular Biology, 2005
Cysteamine or 2-mercaptoethylamine (MEA) is an aminothiol with a well-known radioprotective action. No specific information is available in the literature about the possible chemoprotective action of MEA against genotoxic chemical agents.
Renato Santos-Mello, Luiz Irineu Deimling, Claudio Lauer Júnior, Thaís Rieger de Carvalho   +3 more
doaj   +1 more source

Induction of micronuclei and chromosomal aberrations by the mycotoxin patulin in mammalian cells : role of ascorbic acid as a modulator of patulin clastogenicity

, 2003
Patulin is a mycotoxin produced by several species of Penicillium, Aspergillus and BYSSOCHLAMYS: Patulin is a common contaminant of ripe apples used for the production of apple juice concentrates and is also present in other fruits, vegetables and food ...
Rueff, J., Alves, I., Laires, A., Rodrigues, A. S., Oliveira, N. G.   +4 more
core   +1 more source

FISH in analysis of gamma ray-induced micronuclei formation in barley [PDF]

, 2010
A micronucleus test in combination with fluorescent in situ hybridization (FISH) using telomere-, centromere-specific probes and 5S and 25S rDNA was used for a detailed analysis of the effects of gamma ray irradiation on the root tip meristem cells ...
Juchimiuk-Kwaśniewska, Jolanta, Jolanta Juchimiuk-Kwasniewska, Brodziak, L., Małuszyńska, Jolanta, Lidia Brodziak, Jolanta Maluszynska   +5 more
core   +1 more source

Micronuclei in Kif18a mutant mice form stable micronuclear envelopes and do not promote tumorigenesis.

, 2021
Micronuclei, whole or fragmented chromosomes spatially separated from the main nucleus, are associated with genomic instability and have been identified as drivers of tumorigenesis.
Timothy M. Stearns, Laura G. Reinholdt, Stumpff, Jason, Louise A. Dionne, Reinholdt, Laura G, Whitney Martin, Stearns, Timothy M, Dionne, Louise A, Leslie A. Sepaniac, Jason Stumpff, Sepaniac, Leslie A, Martin, Whitney   +11 more
core   +1 more source

Micronucleus Frequency Test in Epithelial Cells Desquamated From the Oral Mucosa of Patients With Fanconi Anemia

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Fanconi anemia (FA) is a rare genetic disorder predisposing patients to oral squamous cell carcinoma (OSCC). Hematopoietic stem cell transplantation (HSCT) corrects bone marrow failure but may increase the risk of malignancies. Exfoliative cytology and the micronucleus (MN) test provide noninvasive assessment of genomic instability.
Bárbara Soldatelli Ballardin, Pâmela Olivia de Moura, Pedro Leonardo Czmola de Lima, Juliana Lucena Schussel, Cassius Carvalho Torres‐Pereira   +4 more
wiley   +1 more source

Image-based identification and isolation of micronucleated cells to dissect cellular consequences

eLife
Recent advances in isolating cells based on visual phenotypes have transformed our ability to identify the mechanisms and consequences of complex traits.
Lucian DiPeso, Sriram Pendyala, Heather Z Huang, Douglas M Fowler, Emily M Hatch   +4 more
doaj   +1 more source

Micronuclei analysis in the hepatocytes of alcohol-fed rats.

, 2017
Effect of co-enapsulated Probiotic-EGCG on the extent of micronuclei formation in hepatocytes of alcohol administered rats. Values are expressed as percentage of micronucleated cells. *p#p#$pInset- Dividing cells showing binuclei (BN) and micronuclei (MN)
Ujjwal Jit Kaur (3621611), Praveen Rishi (337003), Kanwaljit Chopra (350350), Indu Pal Kaur (2006857), Sumeha Arora (3621608)   +4 more
core   +1 more source

Increased Genetic Instability in Exfoliated Oral Cells in Patients With Epidermolysis Bullosa

Oral Diseases, EarlyView.
ABSTRACT Objective To analyze the nuclear abnormalities of cytotoxicity—karyorrhexis (KR), karyolysis (KL), and pyknosis (PN)—and genotoxicity—micronucleus (MN) in exfoliated cells from different sites of the oral mucosa in patients with Epidermolysis Bullosa (EB) and a control group.
Ana Carolina Sias Franco Franzosi, Rebeca Ferreira Badaró, Lucas Fernandes Leal, Rosalie Matuk Fuentes Torrelio, Willian Grassi Bautz, Leticia Nogueira da Gama‐de‐Souza   +5 more
wiley   +1 more source

Cytomorphological changes of oral mucosal cells among smokeless tobacco users in low and middle-income country settings: new findings from Pakistan

BMC Oral Health
Background Chronic tobacco use, in any form, induces significant cellular alterations in the oral mucosa. This study investigates four distinct cytomorphological changes in oral mucosal cells among smokeless tobacco users, examining their association ...
Sabreen Hassan, Ayesha Sifat, Mohammad Munib, Saleha Saeed, Waqar U. Nisa, Sofia Haider Durrani, Abid Rahim, Naeem Ullah, Saima Afaq, Farhad Ali Khattak, Zia Ul Haq   +10 more
doaj   +1 more source

Single‐Nucleus Transcriptome Analysis Provides New Insights Into B Chromosome Elimination in Sorghum

Plant Biotechnology Journal, EarlyView.
ABSTRACT B chromosomes are supernumerary entities found in many plant species, with some exhibiting tissue‐specific elimination. In Sorghum purpureosericeum, extensive B chromosome elimination occurs during embryogenesis affecting most of the embryonic organs, leaving the B chromosome maintained mainly in limited regions of meristems.
T. Bojdová, P. Abaffy, L. Valihrach, M. Karafiátová, J. Bartoš   +4 more
wiley   +1 more source