Results 91 to 100 of about 26,946 (241)
Validation of the micronucleus-centromere assay for biological dosimetry
Genetics and Molecular Biology, 2000 The micronucleus assay is frequently used for purposes of biological dosimetry. Due to high interindividual variability in the spontaneous frequency of micronuclei, its sensitivity in the low dose region is poor.
Wojcik A. +6 more
doaj
Technical note on cytokinesis-arrested binucleated cell and micronucleus assay
Journal of Radiation and Cancer Research, 2017 Conventionally, many biomarkers are being in use as a measure to genotoxicity in occupational exposure to chemicals, pesticides, radiation, and drug screening. Of which, the micronucleus assay is a preferred choice for many of those applications owing to
Karthik Kanagaraj +5 more
doaj +1 more source
Bacterial infection induces micronuclei formation in VK2/E6E7 cells.
, 2014 VK2/E6E7 cells were infected with N. gonorrhoeae for 24 h. Cytokinesis was blocked with cytochalasin B for 36 h and BNC from infected and control cells were analyzed for micronuclei formation. A.
Katarina Vielfort (204993) +7 more
core +1 more source
Chromosomal and immune dysregulation underlying granular mitosis in glioblastoma
Brain Pathology, EarlyView.Granular mitosis (GM) morphology is linked to PI3K/PTEN pathway alterations, chromosomal disorganization, and impaired innate immunity. Cells exhibiting GM morphology are associated with localized immune responses within their immediate spatial microenvironment.
Rachel Barboza +8 more
wiley +1 more source
Studies of genotoxicity and apoptosis using human lymphocytes or murine neuroblastoma cells exposed in vitro to radiofrequency fields characteristic of mobile phones [PDF]
, 2009 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The aim of the study was to investigate whether non-thermal levels of radiofrequency (RF) fields, characteristic of some mobile phones, might be directly ...
Moquet, Jayne Elizabeth
core +1 more source
Micronuclei and their connection with intracellular innate immunity and viral infection
, 2023 Micronuclei are tiny structures that contain nuclear DNA and a membrane derived from the nucleus. They emerge in cells that have been exposed to severe stress factors, such as viral infections, radiation, or genotoxic substances.
Knoblochová, Kateřina
core
Cancer Science, EarlyView.UV irradiation induces two major types of pyrimidine dimers, CPDs and 6–4PPs. Whereas 6–4PPs efficiently induce cell‐cycle arrest, CPDs do not and frequently persist into S phase. As a result, DSBs can arise in the presence of unrepaired CPDs after 6–4PPs have been repaired, increasing the risk of genomic instability.
Ken‐ichi Yoshioka +2 more
wiley +1 more source
Cell Proliferation, EarlyView.In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar +5 more
wiley +1 more source
ANALYSIS OF SPERMATIDS MICRONUCLEI UNDER THE INFLUENCE OF ACRYLAMIDE [PDF]
, 2011 The micronucleus test is an effective method for determination of the evolution of genotoxic or clastogenic agents of physical and chemical functions.
K. THYAGARAJU +6 more
core +2 more sources
Cytogenetic effects of orthopedic constructions [PDF]
Саратовский научно-медицинский журнал, 2012 Research objective: To estimate cytogenetic effect of dentures on the condition of buccal epithelium by means of the micronuclear test. Materials and methods: For this test the most convenient object of the research is nonkeratinized stratified ...
Scheremetjeva A.S. +5 more
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