Results 71 to 80 of about 26,946 (241)
Micronuclei are abundant in embryos undergoing programmed genome rearrangement.
, 2016 (A) 5-Methylcytosine (5MeC) and trimethyl-H3K9 (H3K9me3) immunolabeling of embryos at 1.5 dpf. (B) Distributions of 5MeC and H3K9me3 in micronuclei during early embryogenesis.
Melissa C. Keinath (3163887) +3 more
core +1 more source
Mitotic clustering of pulverized chromosomes from micronuclei [PDF]
, 2023 Complex genome rearrangements can be generated by the catastrophic pulverization of missegregated chromosomes trapped within micronuclei through a process known as chromothripsis1–5. As each chromosome contains a single centromere, it remains unclear how
Samuel F. Bakhoum +27 more
core +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT The extensive use of pesticides in modern agriculture has raised increasing concerns regarding the potential biological effects of repeated exposure to pesticide residues and commercial formulations. Mancozeb is a widely used ethylene‐bis‐dithiocarbamate fungicide; however, information on its hematological and genotoxic effects following ...
Matheus Henrique Barcelos Figueiredo +10 more
wiley +1 more source
Dual Genotoxic and Antigenotoxic Effects of 3‐Benzoylcoumarins in Mammalian Cells
Journal of Applied Toxicology, EarlyView.ABSTRACT Coumarins are phenolic compounds widely recognized for their diverse pharmacological activities and have attracted increasing attention as potential chemopreventive agents. In the present study, four known 3‐benzoylcoumarin derivatives [(1), (2), (3), and (4)] were evaluated for their cytotoxic, mutagenic, and antigenotoxic effects in Chinese ...
Leticia Helena Parreira +7 more
wiley +1 more source
Folia Oecologica, 2022 The cytogenetic analysis of the Pinus sylvestris L. seed progeny in the forests of the northern taiga in the Far North of Russia conditions was carried out.
Ignatenko Roman Viktorovich +2 more
doaj +1 more source
DNA replication occurs in all lamina positive micronuclei, but never in lamina negative micronuclei [PDF]
Mutagenesis, 2011 A micronucleus is a small nucleus-like structure found in the cytoplasm of dividing cells that suffered from genotoxic stress. It is generally hypothesised that micronuclei content is eventually lost from cells, though the mechanism of how this occurs is unknown.
Atsushi, Okamoto +2 more
openaire +2 more sources
, 2019 Nuclei were detected using DAPI staining. Percentage of micronucleated cells was enumerated according to DAPI staining. Cadmium treatment promotes micronuclei formation compared to untreated cells.
Marianna Ranieri (330759) +10 more
core +1 more source
Cytotoxic and Genotoxic Effects in Buccal Cells of Sandstone Quarry Workers
Journal of Applied Toxicology, EarlyView.ABSTRACT Mineral extraction poses significant occupational health risks, particularly from respirable crystalline silica exposure. Sandstone quarrying generates substantial dust, yet evidence of its genotoxic effects remains limited. This study investigated cytogenotoxic damage in sandstone quarry workers from southern Brazil using the buccal ...
Ana Carolina de Quadros Duarte +6 more
wiley +1 more source
Frontiers in Oncology, 2018 Radiation-induced chromosomal aberrations represent an early marker of late effects, including cell killing and transformation. The measurement of cytogenetic damage in tissues, generally in blood lymphocytes, from patients treated with radiotherapy has ...
Marco Durante, Silvia C. Formenti
doaj +1 more source
Ionic liquids: structure–toxicity relationships, predictive toxicology, and sustainable design
Journal of Chemical Technology &Biotechnology, EarlyView.Abstract Ionic liquids (ILs) have often been described as green alternatives to conventional solvents because of their negligible vapor pressure and highly tunable properties. However, low volatility does not necessarily translate into environmental safety, as their biological and ecological effects are strongly influenced by molecular structure.
Letícia Zanchet +5 more
wiley +1 more source