Results 61 to 70 of about 17,055 (159)

Cytogenetic effects of orthopedic constructions [PDF]

Саратовский научно-медицинский журнал, 2012
Research objective: To estimate cytogenetic effect of dentures on the condition of buccal epithelium by means of the micronuclear test. Materials and methods: For this test the most convenient object of the research is nonkeratinized stratified ...
Scheremetjeva A.S., Salnikova S.N., Salnikov V.N., Konnov V.V., Durnova N.A., Polukhina N.V.   +5 more
doaj  

Chemoprotective effect of cysteamine against the induction of micronuclei by methyl methanesulfonate and cyclophosphamide

Genetics and Molecular Biology, 2005
Cysteamine or 2-mercaptoethylamine (MEA) is an aminothiol with a well-known radioprotective action. No specific information is available in the literature about the possible chemoprotective action of MEA against genotoxic chemical agents.
Renato Santos-Mello, Luiz Irineu Deimling, Claudio Lauer Júnior, Thaís Rieger de Carvalho   +3 more
doaj   +1 more source

Trace Levels of Triclosan May Affect Root Growth and Morphology in Cultivated Plants

Environmental Toxicology, EarlyView.
ABSTRACT Triclosan (TCS) is a micropollutant frequently detected in biosolids applied to agricultural soils. In soil solution—where it is potentially bioavailable to roots—it occurs at residual concentrations (ng L−1). Nevertheless, the ecotoxicological implications of TCS exposure in agricultural crops at these concentrations are still not fully ...
Lizandra de Souza Ratuchinski, Edson Araujo de Almeida, Matheus Cristiano Hermann Massariol, Diego Espirito Santo, Carmem Lúcia Henrich, Bianca da Cruz, Danielle Cristina da Silva de Oliveira, Gideã Taques Tractz, Regiane da Silva Gonzalez, Osvaldo Valarini Junior, Ana Paula Peron   +10 more
wiley   +1 more source

Image-based identification and isolation of micronucleated cells to dissect cellular consequences

eLife
Recent advances in isolating cells based on visual phenotypes have transformed our ability to identify the mechanisms and consequences of complex traits.
Lucian DiPeso, Sriram Pendyala, Heather Z Huang, Douglas M Fowler, Emily M Hatch   +4 more
doaj   +1 more source

Chromosomal and immune dysregulation underlying granular mitosis in glioblastoma

Brain Pathology, EarlyView.
Granular mitosis (GM) morphology is linked to PI3K/PTEN pathway alterations, chromosomal disorganization, and impaired innate immunity. Cells exhibiting GM morphology are associated with localized immune responses within their immediate spatial microenvironment.
Rachel Barboza, Xuan Wang, August Lin, Eric Liu, Pramath Kakodkar, Yayuan Zhao, Quinn Le, Christina A. Castellani, Qi Zhang   +8 more
wiley   +1 more source

Cytomorphological changes of oral mucosal cells among smokeless tobacco users in low and middle-income country settings: new findings from Pakistan

BMC Oral Health
Background Chronic tobacco use, in any form, induces significant cellular alterations in the oral mucosa. This study investigates four distinct cytomorphological changes in oral mucosal cells among smokeless tobacco users, examining their association ...
Sabreen Hassan, Ayesha Sifat, Mohammad Munib, Saleha Saeed, Waqar U. Nisa, Sofia Haider Durrani, Abid Rahim, Naeem Ullah, Saima Afaq, Farhad Ali Khattak, Zia Ul Haq   +10 more
doaj   +1 more source

Splicing Factor Mutations in Clonal Hematopoiesis and Progression to Myeloid Neoplasms

Cancer Science, EarlyView.
Splicing factor (SF)‐mutant CH is characterized by relatively late emergence and accelerated clonal expansion in older individuals. This review summarizes its clonal dynamics, disease‐associated consequences of SF mutations in myeloid neoplasms, and candidate mechanisms that may contribute to age‐dependent selection.
Yang Lyu, Yutong Zhang, Ayana Kon
wiley   +1 more source

Association Between Genotoxic Effects of Ageing Dental Restorations and Micronuclei in Oral Mucosal Cells

Medicina
Background and Objectives: Dental restorations can be composed of various materials, including amalgams and methacrylate-based resins. The health risks associated with the components of the restorative materials have always been a concern, even more so ...
Csilla Benedek, Bernadette Kerekes-Máthé, Zsuzsanna Bardocz-Veres, Boglárka Szabó, Alina Iacob, Alexandra Stoica, Timea Dako, Mónika Kovács, Lóránd Dénes, Liana Bereșescu   +9 more
doaj   +1 more source

Micronucleus Frequency Test in Epithelial Cells Desquamated From the Oral Mucosa of Patients With Fanconi Anemia

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Fanconi anemia (FA) is a rare genetic disorder predisposing patients to oral squamous cell carcinoma (OSCC). Hematopoietic stem cell transplantation (HSCT) corrects bone marrow failure but may increase the risk of malignancies. Exfoliative cytology and the micronucleus (MN) test provide noninvasive assessment of genomic instability.
Bárbara Soldatelli Ballardin, Pâmela Olivia de Moura, Pedro Leonardo Czmola de Lima, Juliana Lucena Schussel, Cassius Carvalho Torres‐Pereira   +4 more
wiley   +1 more source

Increased Genetic Instability in Exfoliated Oral Cells in Patients With Epidermolysis Bullosa

Oral Diseases, EarlyView.
ABSTRACT Objective To analyze the nuclear abnormalities of cytotoxicity—karyorrhexis (KR), karyolysis (KL), and pyknosis (PN)—and genotoxicity—micronucleus (MN) in exfoliated cells from different sites of the oral mucosa in patients with Epidermolysis Bullosa (EB) and a control group.
Ana Carolina Sias Franco Franzosi, Rebeca Ferreira Badaró, Lucas Fernandes Leal, Rosalie Matuk Fuentes Torrelio, Willian Grassi Bautz, Leticia Nogueira da Gama‐de‐Souza   +5 more
wiley   +1 more source