Results 191 to 200 of about 15,743 (258)

The In Vitro Toxicity Profile of Nanoencapsulated Curcumin in a Chitosan-Alginate Gel Carrier Using Rabbit Lymphocytes: Preliminary Research. [PDF]

Int J Mol Sci
Kuchta-Gładysz M, Wojciechowska-Puchałka J, Grzesiakowska-Dul A, Kmiecik M, Khachatryan K, Khachatryan G.   +5 more
europepmc   +1 more source

Development of a DNA damage assay system using stable human hepatocytes. [PDF]

Genes Environ
Mishima M, Izawa K, Tsuda M, Higuchi Y, Uehara S, Suemizu H, Sugiyama KI.   +6 more
europepmc   +1 more source

Comprehensive Evaluation of the Genotoxic Potential of Food Additive Titanium Dioxide in Human Intestinal Cell Systems. [PDF]

Int J Mol Sci
Nam HN, Jeong SM, Kim SB, Choi SJ.
europepmc   +1 more source

The Genetic and Embryo-Fetal Developmental Toxicity Profile of the Novel Transgelin Agonist Deg-AZM: Ames, Micronucleus, Chromosomal Aberration, and Rat EFD Studies. [PDF]

Biomedicines
Gu X, Xu Y, Liu N, Li K, Wang X, Zhang J, Zhang X, Ding Y, Li X, Zhou H, Ai X, Yang C.   +11 more
europepmc   +1 more source

An In Vitro and In Vivo Assessment of the Genotoxic Potential of Maizinol (UP165), a Zea mays Leaf Extract. [PDF]

J Appl Toxicol
Weston JK, Lynch BS, Akingbasote JA.
europepmc   +1 more source

Updated safety evaluation of the food enzyme AMP deaminase from the non-genetically modified <i>Streptomyces murinus</i> strain AE-DNTS. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Criado A, Liu Y.   +14 more
europepmc   +1 more source

LncRNA DANCR Regulates PARP1-Mediated Oxidative Stress Response in Corneas by Encoding a Novel Micropeptide miPEPDR. [PDF]

Invest Ophthalmol Vis Sci
Ma X, Hao J, Ben Hilal H, Cheng Z, Feng P, Song J, Yang J, Chen P, Chen W, Li X.   +9 more
europepmc   +1 more source

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Sampling times in micronucleus testing

Mutation Research Letters, 1992
A series of micronucleus inducers were evaluated in the mouse bone marrow micronucleus test to determine if a 72-h sampling time enhances the sensitivity for detecting genotoxic agents. Male and female Swiss albino mice were dosed once with 7,12- dimethylbenz[a]anthracene, 6-mercaptopurine, benzo[a]pyrene, benzene, cyclophosphamide, 2 ...
P, Vanparys, G, Deknudt, F, Vermeiren, M, Sysmans, R, Marsboom   +4 more
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The micronucleus test methodological aspects

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1973
Abstract Changes in the cellular compositiion of bone marrow were studied in relation to dose of Trenimon® and time after treatment. Strong mutagenic effects caused a partial depletion of the marrow cavities of nucleated blood cell precursors, with subsequent retention of newly formed erythrocytes and inundation with peripheral blood.
Von Ledebur, M, Schmid, Werner
openaire   +2 more sources

The automated bone marrow micronucleus test

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1989
A new technology is presented which offers high-quality slides enabling the fully automated scoring of large quantities of erythrocytic cells for micronuclei by computerized image analysis. The techniques are applicable to bone marrow specimens as well as to peripheral blood obtained from various species of laboratory animals as well as from man.
F, Romagna, C D, Staniforth
openaire   +2 more sources