Results 171 to 180 of about 24,556,719 (242)

Organ-on-a-Chip Models—New Possibilities in Experimental Science and Disease Modeling

Biomolecules
‘Organ-on-a-chip’ technology is a promising and rapidly evolving model in biological research. This innovative microfluidic cell culture device was created using a microchip with continuously perfused chambers, populated by living cells arranged to ...
Bartłomiej Wysoczański, Marcin Świątek, Anna Wójcik-Gładysz   +2 more
doaj   +1 more source

Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload. [PDF]

, 2018
The integration of in vitro cardiac tissue models, human induced pluripotent stem cells (hiPSCs) and genome-editing tools allows for the enhanced interrogation of physiological phenotypes and recapitulation of disease pathologies.
Boggess, Steven, Conklin, Bruce R, Grigoropoulos, Costas P, Healy, Kevin E, Huebsch, Nathaniel, Koo, Sangmo, Ma, Zhen, Mandegar, Mohammad A, Siemons, Brian   +8 more
core   +1 more source

Development of an Easy-to-Fabricate Microdevice for Three-Dimensional Culture and Its Application to Glomerular Endothelial Cell Culture

Micromachines
The development of an organ-on-a-chip to reproduce organ functions requires the incorporation of a vascular network within the tissue to transport the necessary nutrients.
Miyu Yamazaki, Yasuko Kobayashi, Kiichi Sato   +2 more
doaj   +1 more source

Aerospace medicine and biology: A continuing bibliography with indexes, supplement 130, July 1974 [PDF]

This special bibliography lists 291 reports, articles, and other documents introduced into the NASA scientific and technical information system in June ...

core   +1 more source

Engineering Challenges in Microphysiological Systems [PDF]

Future Science OA, 2017
openaire   +2 more sources

De novo establishment of an ex vivo culture for living myocardial slices applying a microphysiological system – MPSlms

Current Directions in Biomedical Engineering
Cardiovascular disease is a global health burden. To develop novel treatment options complex in vitro model systems are needed that resemble the pathophysiological situation ex vivo.
Jordan Maria, Schmieder Florian, Waleczek Florian J. G., Polk Christoph, Stucki-Koch Angelika, Philipp Jürgen, Dietzel Leila, Clement Alexander, Behrens Stephan, Thum Thomas, Sonntag Frank, Fiedler Jan   +11 more
doaj   +1 more source

Exploring the synergy of CRISPR and microphysiological systems

ALTEX
Since its discovery as an innate bacterial immune system, the Clustered regularly interspaced short palindromic repeats (CRISPR) associated nuclease 9 (CRISPR-Cas9) system has quickly landed on mammalian genomes to become the first-in-class editing technique.
Emanuele, Celauro, Amer, Saleh, Prathap K, Mahalingaiah, Lisa, Mohamet, Rhiannon, David, Roberto, Nitsch   +5 more
openaire   +2 more sources

A NAMs-Based Microphysiological System for Metastasis and Mechanobiology Studies. [PDF]

Thorac Res Pract
Dogan B, Saglam-Metiner P, Goksel T, Yesil-Celiktas O.   +3 more
europepmc   +1 more source

Closed, pumpless microphysiological system with unidirectional flow for co-culture and focal irradiation. [PDF]

RSC Adv
Ueno H, Hanamura K, Aoki Y, Yamamura M, Shirao T, Suzuki T.   +5 more
europepmc   +1 more source

Enhanced operation of female reproductive microphysiological system (MPS) for rapid mechanistic study. [PDF]

Micro Nano Syst Lett
Lam PY, Kim S, Jung H, Cherukuri R, Menon R, Han A.   +5 more
europepmc   +1 more source