Results 181 to 190 of about 4,549 (220)

Microphysiological system with integrated sensors to study the effect of pulsed electric field. [PDF]

open access: yesSci Rep
Bakute N   +6 more
europepmc   +1 more source

Adipo-on-chip: a microphysiological system to culture human mesenchymal stem cells with improved adipogenic differentiation. [PDF]

open access: yesIn Vitro Model
de Souza IR   +4 more
europepmc   +1 more source

Microphysiological Systems for Neurodegenerative Diseases in Central Nervous System [PDF]

open access: yesMicromachines, 2020
Neurodegenerative diseases are among the most severe problems in aging societies. Various conventional experimental models, including 2D and animal models, have been used to investigate the pathogenesis of (and therapeutic mechanisms for ...
Mihyeon Bae   +2 more
exaly   +7 more sources

Engineering Microphysiological Immune System Responses on Chips [PDF]

open access: yesTrends in Biotechnology, 2020
Tissues- and organs-on-chips are microphysiological systems (MPSs) that model the architectural and functional complexity of human tissues and organs that is lacking in conventional cell monolayer cultures.
Chris P Miller   +2 more
exaly   +5 more sources

Study of the Anticancer Potential of Plant Extracts Using Liver Tumor Microphysiological System [PDF]

open access: yesLife, 2022
Background: Plants have been considered a vital source of modern pharmaceutics since the paleolithic age. Contemporary chemotherapeutic drugs for cancer therapy are chemical entities sourced from plants. However, synthetic drugs or their derivatives come
Hafiz Muhammad Umer Farooqi   +2 more
exaly   +2 more sources
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Imaging microphysiological systems: a review

American Journal of Physiology-Cell Physiology, 2021
Microphysiological systems (MPS), often referred to as “organ-on-chips,” are microfluidic-based in vitro models that aim to recapitulate the dynamic chemical and mechanical microenvironment of living organs. MPS promise to bridge the gap between in vitro and in vivo models and ultimately improve the translation from preclinical animal studies to ...
Samantha, Peel, Mark, Jackman
openaire   +2 more sources

Microphysiological system design: simplicity is elegance

open access: yesCurrent Opinion in Biomedical Engineering, 2020
Design parameters for microphysiological systems (MPS) are driven by the need for new tools to answer questions focusing on human physiology in a robust and reliable manner. Within this perspective, engineering benchmarks and principles are identified to guide the construction of new devices in the MPS field, with emphasis placed on the design ...
Samuel S Hinman   +2 more
exaly   +4 more sources

Microphysiological systems of the placental barrier

Advanced Drug Delivery Reviews, 2020
Methods to evaluate maternal-fetal transport across the placental barrier have generally involved clinical observations after-the-fact, ex vivo perfused placenta studies, or in vitro Transwell assays. Given the ethical and technical limitations in these approaches, and the drive to understand fetal development through the lens of transport-induced ...
Navein, Arumugasaamy   +4 more
openaire   +2 more sources

Integrated biosensors for monitoring microphysiological systems

Lab on a Chip, 2022
This review discusses the state-of-the-art integrated biosensors by providing specific examples, detailing their main advantages in monitoring MPSs, and describing the remaining challenges and potential future developments.
Lei Mou   +10 more
openaire   +2 more sources

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