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Integrated biosensors for monitoring microphysiological systems
Lab on a Chip, 2022This review discusses the state-of-the-art integrated biosensors by providing specific examples, detailing their main advantages in monitoring MPSs, and describing the remaining challenges and potential future developments.
Lei Mou +10 more
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Microphysiological systems of the placental barrier
Advanced Drug Delivery Reviews, 2020Methods to evaluate maternal-fetal transport across the placental barrier have generally involved clinical observations after-the-fact, ex vivo perfused placenta studies, or in vitro Transwell assays. Given the ethical and technical limitations in these approaches, and the drive to understand fetal development through the lens of transport-induced ...
Navein, Arumugasaamy +4 more
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Human microphysiological systems for drug development
Science, 2021Organs-on-chips could be used to assess drug efficacy and support personalized ...
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Microphysiological system as a promising technology for drug assay
Folia Pharmacologica Japonica, 2019 MPS (microphysiological system) is in-vitro cell-culture environment, which is precisely maintained in a micro space manufactured using MEMS (micro electro mechanical systems) technology, to derive in-vivo like functions from human cells. From the viewpoint of pharmacokinetics, it can be considered as a wet PBPK/PD simulator consisting of the micro ...
Seiichi Ishida, Toshiyuki Kanamori
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Microphysiological Systems for Cancer Immunotherapy Research and Development
Advanced Biology, 2023AbstractCancer immunotherapy focuses on the use of patients’ adaptive immune systems to combat cancer. In the past decade, FDA has approved many immunotherapy products for cancer patients who suffer from primary tumors, tumor relapse, and metastases. However, these immunotherapies still show resistance in many patients and often lead to inconsistent ...
Yansong Peng, Esak Lee
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Microfluidic-based vascularized microphysiological systems
Lab on a Chip, 2018Microphysiological systems have emerged in the last decade to provide an alternative to in vivo models in basic science and pharmaceutical research.
Somin Lee +6 more
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Vascular microphysiological systems
Current Opinion in HematologyPurpose of review This review summarizes innovations in vascular microphysiological systems (MPS) and discusses the themes that have emerged from recent works. Recent findings Vascular MPS are increasing in complexity and ability to replicate tissue.
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Microphysiological systems inspired by leaf venation
Trends in BiotechnologyNature-inspired microfluidic networks are revolutionizing microphysiological systems, allowing for the precise emulation of human physiology. This article delves into the fabrication techniques of leaf-venation-inspired (LVI) microfluidic networks and explores their transformative applications in organ-on-a-chip and tissue engineering, showcasing their
Mao Mao +3 more
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Microphysiological Systems: A Cellular Dilemma
2021Presentation to the Microphysiological Systems (MPS) Webinar: Bridging Human and Animal Research January ...
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