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Microphysiological systems inspired by leaf venation

Trends in Biotechnology
Nature-inspired microfluidic networks are revolutionizing microphysiological systems, allowing for the precise emulation of human physiology. This article delves into the fabrication techniques of leaf-venation-inspired (LVI) microfluidic networks and explores their transformative applications in organ-on-a-chip and tissue engineering, showcasing their
Mao Mao   +3 more
openaire   +2 more sources

Biologically-Inspired Microphysiological Systems

2019
Microphysiological multi-organ devices are designed to mimic the physiological interaction of various interconnected organ models, by successfully imitating organismal functionality and response to substances. The first concepts of in vitro multi-organ systems were put forward in the late 1980s, demonstrating that such systems could provide mechanistic
Dehne, Eva Maria   +2 more
openaire   +2 more sources

Microphysiological Systems: A Cellular Dilemma

2021
Presentation to the Microphysiological Systems (MPS) Webinar: Bridging Human and Animal Research January ...
openaire   +1 more source

The potential of neural microphysiological systems (MPS)

Folia Pharmacologica Japonica
In vitro compound evaluation using human-derived neural cells is beginning to incorporate microphysiological systems (MPS). Neural MPS includes not only microfluidic devices but has also recently recognized neural organoids as viable MPS platforms. The history of neural MPS utilizing microfluidic devices is extensive, with the development of models ...
openaire   +2 more sources

Microphysiological Models of the Respiratory System

2019
The lung is an essential organ that shows remarkable complexity in its structure, environment, and function. Mimicking this dynamic and complex organ in experimental model systems remains a major challenge in biomedical research. Here we review recent research efforts directed towards leveraging microfluidic cell culture techniques to develop ...
openaire   +1 more source

Microphysiological system with continuous analysis of albumin for hepatotoxicity modeling and drug screening

Journal of Industrial and Engineering Chemistry, 2021
Arun Asif   +2 more
exaly  

Assessment of the toxicity of acrolein on an alveolus microphysiological system

Environmental Toxicology and Pharmacology
With the advancement of industrialization, public concerns about air pollution have been increasing. As the primary site of gas exchange in the respiratory system, the human lung is highly susceptible to the toxic effects of environmental pollutants.
Yanfei, Xu   +3 more
openaire   +2 more sources

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