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Microphysiological systems inspired by leaf venation
Trends in BiotechnologyNature-inspired microfluidic networks are revolutionizing microphysiological systems, allowing for the precise emulation of human physiology. This article delves into the fabrication techniques of leaf-venation-inspired (LVI) microfluidic networks and explores their transformative applications in organ-on-a-chip and tissue engineering, showcasing their
Mao Mao +3 more
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Biosensors & bioelectronics
Skeletal muscle is essential for maintaining body shape and supporting physiological processes. Musculoskeletal function is influenced by various factors, including nutrition, infection, injury or trauma, and advanced glycation end-products (AGEs), which
Jaesang Kim +9 more
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Skeletal muscle is essential for maintaining body shape and supporting physiological processes. Musculoskeletal function is influenced by various factors, including nutrition, infection, injury or trauma, and advanced glycation end-products (AGEs), which
Jaesang Kim +9 more
semanticscholar +1 more source
Vascular microphysiological systems
Current Opinion in HematologyPurpose of review This review summarizes innovations in vascular microphysiological systems (MPS) and discusses the themes that have emerged from recent works. Recent findings Vascular MPS are increasing in complexity and ability to replicate tissue.
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Microphysiological Systems: A Cellular Dilemma
2021Presentation to the Microphysiological Systems (MPS) Webinar: Bridging Human and Animal Research January ...
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Food and Chemical Toxicology
To compensate the limitation of animal models, new models were proposed for drug safety evaluation to refine and reduce existing models. To mimic drug absorption and metabolism and predict toxicokinetic and toxic effects in an in vitro intestinal-liver ...
Yue Yu +9 more
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To compensate the limitation of animal models, new models were proposed for drug safety evaluation to refine and reduce existing models. To mimic drug absorption and metabolism and predict toxicokinetic and toxic effects in an in vitro intestinal-liver ...
Yue Yu +9 more
semanticscholar +1 more source
Advances in Biology
The average cost to bring a new drug from its initial discovery to a patient's bedside is estimated to surpass $2 billion and requires over a decade of research and development.
Landys Lopez Quezada +10 more
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The average cost to bring a new drug from its initial discovery to a patient's bedside is estimated to surpass $2 billion and requires over a decade of research and development.
Landys Lopez Quezada +10 more
semanticscholar +1 more source
Biosensors & bioelectronics
Well plates are widely used in biological experiments, particularly in pharmaceutical sciences and cell biology. Its popularity stems from its versatility to support a variety of fluorescent markers for high throughput monitoring of cellular activities ...
Ming-Hao Cheng +6 more
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Well plates are widely used in biological experiments, particularly in pharmaceutical sciences and cell biology. Its popularity stems from its versatility to support a variety of fluorescent markers for high throughput monitoring of cellular activities ...
Ming-Hao Cheng +6 more
semanticscholar +1 more source
Acta Biomaterialia
BACKGROUND Calcific aortic valve disease (CAVD) is one of the most common forms of valvulopathy, with a 50% elevated risk of a fatal cardiovascular event, and greater than 15,000 annual deaths in North America alone.
Ishita Tandon +18 more
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BACKGROUND Calcific aortic valve disease (CAVD) is one of the most common forms of valvulopathy, with a 50% elevated risk of a fatal cardiovascular event, and greater than 15,000 annual deaths in North America alone.
Ishita Tandon +18 more
semanticscholar +1 more source
Toxicology in Vitro
Concerns over Bisphenol A (BPA) and its substitute, Bisphenol S (BPS), have led to innovative exploration due to potential adverse health effects. BPS, replacing BPA in some regions to avoid toxic impacts, remains insufficiently studied.
Melissa Dibbernn Ganzerla +13 more
semanticscholar +1 more source
Concerns over Bisphenol A (BPA) and its substitute, Bisphenol S (BPS), have led to innovative exploration due to potential adverse health effects. BPS, replacing BPA in some regions to avoid toxic impacts, remains insufficiently studied.
Melissa Dibbernn Ganzerla +13 more
semanticscholar +1 more source