Prognostic Role of MicroRNA-210 in Various Carcinomas: A Systematic Review and Meta-Analysis [PDF]
Minmin Li +6 more
openalex +1 more source
RNA Modifications: Current Understandings and Future Perspectives
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao +7 more
wiley +1 more source
Role of microRNA-210-3p in hepatitis B virus-related hepatocellular carcinoma [PDF]
Asahiro Morishita +19 more
openalex +1 more source
Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang +12 more
wiley +1 more source
The microRNA-210-Stathmin1 Axis Decreases Cell Stiffness to Facilitate the Invasiveness of Colorectal Cancer Stem Cells. [PDF]
Liao TT +13 more
europepmc +1 more source
Targeting Tumor Stroma: Current Challenges and Future Directions
Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang +7 more
wiley +1 more source
Histone Modifications in Cardiovascular Disease: Mechanisms and Therapeutic Opportunities
This graphical abstract summarizes how classical and emerging histone posttranslational modifications (PTMs), together with their chromatin regulators (writers, erasers, and readers), govern major pathobiological programs in cardiovascular disease.
Yu Zheng +8 more
wiley +1 more source
MicroRNA-210 Mediates Hypoxia-Induced Repression of Spontaneous Transient Outward Currents in Sheep Uterine Arteries During Gestation. [PDF]
Hu XQ +5 more
europepmc +1 more source
Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract
ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik +3 more
wiley +1 more source
Evidence of emerging transcriptome mediators of Alzheimer's disease in canine cognitive dysfunction
Canine cognitive dysfunction (CCD) may be a promising model of Alzheimer's disease (AD). To assess AD‐related molecular signatures in CCD, we generated transcriptome data on dog cortex and plasma extracellular vesicles (EVs). CCD‐related transcriptome changes were similar to those in aging/AD humans and were detectable in EVs from the same animals ...
Shelby C. Osburn +7 more
wiley +1 more source

